Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
Redding, Sy, Sternberg, Samuel H., Marshall, Myles, Gibb, Bryan, Bhat, Prashant, Guegler, Chantal K., Wiedenheft, Blake, Doudna, Jennifer A., Greene, Eric C.
Published in Cell (05.11.2015)
Published in Cell (05.11.2015)
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High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
Boyle, Evan A., Andreasson, Johan O. L., Chircus, Lauren M., Sternberg, Samuel H., Wu, Michelle J., Guegler, Chantal K., Doudna, Jennifer A., Greenleaf, William J.
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
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CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
Hochstrasser, Megan L., Taylor, David W., Bhata, Prashant, Guegler, Chantal K., Sternberg, Samuel H., Nogales, Eva, Doudna, Jennifer A.
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
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A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin–antitoxin system
Guegler, Chantal K, Teodoro, Gabriella I C, Srikant, Sriram, Chetlapalli, Keerthana, Doering, Christopher R, Ghose, Dia A, Laub, Michael T
Published in Nucleic acids research (09.02.2024)
Published in Nucleic acids research (09.02.2024)
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Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
Ietswaart, Robert, Smalec, Brendan M., Xu, Albert, Choquet, Karine, McShane, Erik, Jowhar, Ziad Mohamoud, Guegler, Chantal K., Baxter-Koenigs, Autum R., West, Emma R., Fu, Becky Xu Hua, Gilbert, Luke, Floor, Stephen N., Churchman, L. Stirling
Published in Molecular cell (25.07.2024)
Published in Molecular cell (25.07.2024)
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Target Recognition and Degradation by an Adaptive Bacterial Immune System
Hochstrasser, Megan L., Taylor, David W., Bhat, Prashant, Guegler, Chantal K., Doudna, Jennifer A.
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
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Targeting and Degradation of Viral DNA by the CRISPR-Cas System of Escherichia Coli
Redding, Sy, Sternberg, Samuel H., Bhat, Prashant, Guegler, Chantal K., Hochstrasser, Megan L., Wiedenheft, Blake, Doudna, Jennifer A., Greene, Eric C.
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
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