S808 Mechanisms of Non-Response to Adalimumab on Inflammatory Bowel Disease: Peripheral Proteomic and Transcriptomic Profiling from the SERENE-CD and SERENE-UC Studies
Panés, Julian, Verstockt, Bram, Pivorunas, Valerie, Butler, James, Mahi, Naim, Ruzek, Melanie, Sornasse, Thierry, Fann, James, Hong, Feng, Cao, Xiaohong, Smaoui, Nizar, Davis, Justin Wade, Kalabic, Jasmina, Song, Alexandra, Guay, Heath, Salas, Azucena, Kennedy, Nick, Ahmad, Tariq, Vermeire, Severine
Published in The American journal of gastroenterology (01.10.2021)
Published in The American journal of gastroenterology (01.10.2021)
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Journal Article
S809 A Higher Induction Dosing Regimen of Adalimumab Does Not Enhance Modulation of Downstream Blood Molecular Markers in Patients With Moderately to Severely Active Crohn’s Disease or Ulcerative Colitis
Ferrante, Marc, Pivorunas, Valerie, Butler, James, Mahi, Naim, Mostafa, Nael, Ruzek, Melanie, Fann, James, Hong, Feng, Cao, Xiaohong, Smaoui, Nizar, Davis, Justin Wade, Kalabic, Jasmina, Song, Alexandra, Guay, Heath, Rieder, Florian, Panés, Julian, Colombel, Jean-Frederic
Published in The American journal of gastroenterology (01.10.2021)
Published in The American journal of gastroenterology (01.10.2021)
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Journal Article
IL-21 receptor is critical for the development of memory B cell responses
Rankin, Andrew L, MacLeod, Heather, Keegan, Sean, Andreyeva, Tatyana, Lowe, Leslie, Bloom, Laird, Collins, Mary, Nickerson-Nutter, Cheryl, Young, Deborah, Guay, Heath
Published in The Journal of immunology (1950) (15.01.2011)
Published in The Journal of immunology (1950) (15.01.2011)
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Journal Article
MyD88 Is Required for the Formation of Long-Term Humoral Immunity to Virus Infection
Guay, Heath M, Andreyeva, Tatyana A, Garcea, Robert L, Welsh, Raymond M, Szomolanyi-Tsuda, Eva
Published in Journal of Immunology (15.04.2007)
Published in Journal of Immunology (15.04.2007)
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Journal Article
Generation of Protective T Cell-Independent Antiviral Antibody Responses in SCID Mice Reconstituted with Follicular or Marginal Zone B Cells
Guay, Heath M, Mishra, Rabinarayan, Garcea, Robert L, Welsh, Raymond M, Szomolanyi-Tsuda, Eva
Published in The Journal of immunology (1950) (01.07.2009)
Published in The Journal of immunology (1950) (01.07.2009)
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Journal Article
The antiviral CD8+ T cell response is differentially dependent on CD4+ T cell help over the course of persistent infection
Kemball, Christopher C, Pack, Christopher D, Guay, Heath M, Li, Zhu-Nan, Steinhauer, David A, Szomolanyi-Tsuda, Eva, Lukacher, Aron E
Published in The Journal of immunology (1950) (15.07.2007)
Published in The Journal of immunology (1950) (15.07.2007)
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Journal Article
In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus
Vugmeyster, Yulia, Guay, Heath, Szklut, Pamela, Qian, Ming D., Jin, Macy, Widom, Angela, Spaulding, Vikki, Bennett, Frann, Lowe, Leslie, Andreyeva, Tatyana, Lowe, David C., Lane, Steven, Thom, George, Valge-Archer, Viia, Gill, Davinder, Young, Deborah, Bloom, Laird
Published in mAbs (01.05.2010)
Published in mAbs (01.05.2010)
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Journal Article
CD4+ T Cells Recognizing a Single Self-Peptide Expressed by APCs Induce Spontaneous Autoimmune Arthritis
Rankin, Andrew L, Reed, Amy J, Oh, Soyoung, Cozzo Picca, Cristina, Guay, Heath M, Larkin, Joseph, III, Panarey, Laura, Aitken, Malinda K, Koeberlein, Brigitte, Lipsky, Peter E, Tomaszewski, John E, Naji, Ali, Caton, Andrew J
Published in The Journal of immunology (1950) (15.01.2008)
Published in The Journal of immunology (1950) (15.01.2008)
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Journal Article
Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys
Vugmeyster, Yulia, Allen, Scott, Szklut, Pamela, Bree, Andrea, Ryan, Mark, Ma, Margery, Spaulding, Vikki, Young, Deborah, Guay, Heath, Bloom, Laird, Leach, Michael W, O'Toole, Margot, Adkins, Karissa
Published in Journal of translational medicine (26.04.2010)
Published in Journal of translational medicine (26.04.2010)
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Journal Article
Specificity-Based Negative Selection of Autoreactive B Cells during Memory Formation
Guay, Heath M, Panarey, Laura, Reed, Amy J, Caton, Andrew J
Published in The Journal of immunology (1950) (01.11.2004)
Published in The Journal of immunology (1950) (01.11.2004)
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Journal Article
The Clinical Response of Upadacitinib and Risankizumab Is Associated With Reduced Inflammatory Bowel Disease Anti-TNF-α Inadequate Response Mechanisms
Wang, Jing, Macoritto, Michael, Guay, Heath, Davis, Justin W, Levesque, Marc C, Cao, Xiaohong
Published in Inflammatory bowel diseases (02.05.2023)
Published in Inflammatory bowel diseases (02.05.2023)
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Journal Article
HLA-DQA105 Associates With Anti-Tumor Necrosis Factor Immunogenicity and Low Adalimumab Trough Concentrations in Inflammatory Bowel Disease Patients From the SERENE Ulcerative Colitis and Crohn’s Disease Studies
Reppell, Mark, Zheng, Xiuwen, Dreher, Ingeborg, Blaes, Jonas, Regan, Elina, Haslberger, Tobias, Guay, Heath, Pivorunas, Valerie, Smaoui, Nizar
Published in Journal of Crohn's and colitis (19.09.2024)
Published in Journal of Crohn's and colitis (19.09.2024)
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Journal Article
150: BIOMARKERS FOR IBD USING OLINK PROTEOMICS INFLAMMATION PANEL: PRELIMINARY RESULTS FROM THE COLLIBRI CONSORTIUM
Sudhakar, Padhmanand, Salomon, Benita, Verstockt, Bram, Ungaro, Ryan C., Aden, Konrad, D'Haens, Geert, Komori, Kiyomi, Guay, Heath M., Silverberg, Mark S., Vermeire, Séverine, Halfvarson, Jonas
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Journal Article
Tu1457: BASELINE WHOLE-BLOOD GENE EXPRESSION OF TREM1 DOES NOT PREDICT CLINICAL OR ENDOSCOPIC OUTCOMES FOLLOWING ADALIMUMAB TREATMENT IN PATIENTS WITH ULCERATIVE COLITIS OR CROHN'S DISEASE IN THE SERENE STUDIES
Verstockt, Bram, Mahi, Naim Al, Pivorunas, Valerie L., Smaoui, Nizar, Guay, Heath M., Kennedy, Nicholas A., Hanauer, Stephen B., Ferrante, Marc, Panés, Julian, Vermeire, Séverine
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Journal Article
817 Identification of Biomarkers and Mechanistic Insight for Upadacitinib in Crohn’s Disease: Serum Inflammatory Mediator Analysis From the Phase 2b CELEST Study
Séverine, Vermeire, Guay, Heath, Verstockt, Bram, Hong, Feng, Lee, Wan-Ju, Cataldi, Fabio, Lacerda, Ana, Danese, Silvio
Published in The American journal of gastroenterology (01.10.2019)
Published in The American journal of gastroenterology (01.10.2019)
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