PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination
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Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques
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Published in Science (American Association for the Advancement of Science) (23.07.2004)
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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells
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Published in Journal of medicinal chemistry (13.02.2003)
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Fourier Transform Mass Spectrometry and Nuclear Magnetic Resonance Analysis for the Rapid and Accurate Characterization of Hexacosanoylceramide
Ross, Charles W, Simonsick, William J, Bogusky, Michael J, Celikay, Recep W, Guare, James P, Newton, Randall C
Published in International journal of molecular sciences (01.07.2016)
Published in International journal of molecular sciences (01.07.2016)
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A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase
Hazuda, Daria J., Anthony, Neville J., Gomez, Robert P., Jolly, Samson M., Wai, John S., Zhuang, Linghang, Fisher, Thorsten E., Embrey, Mark, Guare, James P., Egbertson, Melissa S., Vacca, Joseph P., Huff, Joel R., Felock, Peter J., Witmer, Marc V., Stillmock, Kara A., Danovich, Robert, Grobler, Jay, Miller, Michael D., Espeseth, Amy S., Jin, Lixia, I-Wu Chen, Lin, Jiunn H., Kassahun, Kelem, Ellis, Joan D., Wong, Bradley K., Xu, Wei, Pearson, Paul G., Schleif, William A., Cortese, Riccardo, Emini, Emilio, Summa, Vincenzo, Holloway, M. Katharine, Young, Steven D., Coffin, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
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L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor
Dorsey, Bruce D, Levin, Rhonda B, McDaniel, Stacy L, Vacca, Joseph P, Guare, James P, Darke, Paul L, Zugay, Joan A, Emini, Emilio A, Schleif, William A
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells
Wai, John S, Egbertson, Melissa S, Payne, Linda S, Fisher, Thorsten E, Embrey, Mark W, Tran, Lekhanh O, Melamed, Jeffrey Y, Langford, H. Marie, Guare, James P, Zhuang, Linghang, Grey, Vanessa E, Vacca, Joseph P, Holloway, M. Katharine, Naylor-Olsen, Adel M, Hazuda, Daria J, Felock, Peter J, Wolfe, Abigail L, Stillmock, Kara A, Schleif, William A, Gabryelski, Lori J, Young, Steven D
Published in Journal of medicinal chemistry (28.12.2000)
Published in Journal of medicinal chemistry (28.12.2000)
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A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors
Guare, James P., Wai, John S., Gomez, Robert P., Anthony, Neville J., Jolly, Samson M., Cortes, Amanda R., Vacca, Joseph P., Felock, Peter J., Stillmock, Kara A., Schleif, William A., Moyer, Gregory, Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Hazuda, Daria J., Young, Steven D.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines
Bell, Ian M, Erb, Jill M, Freidinger, Roger M, Gallicchio, Steven N, Guare, James P, Guidotti, Maribeth T, Halpin, Rita A, Hobbs, Doug W, Homnick, Carl F, Kuo, Michelle S, Lis, Edward V, Mathre, David J, Michelson, Stuart R, Pawluczyk, Joseph M, Pettibone, Douglas J, Reiss, Duane R, Vickers, Stanley, Williams, Peter D, Woyden, Carla J
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Published in Journal of medicinal chemistry (04.06.1998)
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Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors
Lyle, Terry A, Wiscount, Catherine M, Guare, James P, Thompson, Wayne J, Anderson, Paul S, Darke, Paul L, Zugay, Joan A, Emini, Emilio A, Schleif, William A
Published in Journal of medicinal chemistry (01.03.1991)
Published in Journal of medicinal chemistry (01.03.1991)
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HIV PROTEASE INHIBITORS USEFUL FOR THE TREATMENT OF AIDS
HUNGATE, RANDALL W, GUARE, JAMES P, VACCA, JOSEPH P, DORSEY, BRUCE D, HOLLOWAY M. KATHARINE
Year of Publication 15.12.2000
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Year of Publication 15.12.2000
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A Priori Prediction of Activity for HIV-1 Protease Inhibitors Employing Energy Minimization in the Active Site
Holloway, M. Katharine, Wai, Jenny M, Halgren, Thomas A, Fitzgerald, Paula M. D, Vacca, Joseph P, Dorsey, Bruce D, Levin, Rhonda B, Thompson, Wayne J, Chen, L. Jenny, deSolms, S. Jane, Gaffin, Neil, Ghosh, Arun K, Giuliani, Elizabeth A, Graham, Samuel L, Guare, James P, Hungate, Randall W, Lyle, Terry A, Sanders, William M, Tucker, Thomas J, Wiggins, Mark, Wiscount, Catherine M, Woltersdorf, Otto W, Young, Steven D, Darke, Paul L, Zugay, Joan A
Published in Journal of medicinal chemistry (24.05.1996)
Published in Journal of medicinal chemistry (24.05.1996)
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Pyridinylpiperazines, a new class of selective .alpha.2-adrenoceptor antagonists
Saari, Walfred S, Halczenko, Wasyl, King, Stella W, Huff, Joel R, Guare, James P, Hunt, Cecilia A, Randall, William C, Anderson, Paul S, Lotti, Victor J
Published in Journal of medicinal chemistry (01.12.1983)
Published in Journal of medicinal chemistry (01.12.1983)
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Design and synthesis of HIV protease inhibitors. Variations of the carboxyterminus of the HIV protease inhibitor L-682,679
DeSolms, S. Jane, Giuliani, Elizabeth A, Guare, James P, Vacca, Joseph P, Sanders, William M, Graham, Samuel L, Wiggins, J. Mark, Darke, Paul L, Sigal, Irving S
Published in Journal of medicinal chemistry (01.09.1991)
Published in Journal of medicinal chemistry (01.09.1991)
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SUBSTITUTED HEXAHYDRO ARYL QUINOLIZINES
SOLMS JANE, YOUNG STEVEN D, HUFF JOEL R, GUARE JAMES P, BALDWIN JOHN J, VACCA JOSEPH P
Year of Publication 30.06.1990
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Year of Publication 30.06.1990
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Structure-affinity relationships of arylquinolizines at .alpha.-adrenoceptors
Huff, Joel R, Baldwin, John J, DeSolms, S. Jane, Guare, James P, Hunt, Cecilia A, Randall, William C, Sanders, William S, Smith, Steven J, Vacca, Joseph P, Zrada, Matthew M
Published in Journal of medicinal chemistry (01.03.1988)
Published in Journal of medicinal chemistry (01.03.1988)
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