Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia
Zhao, Xiao-Yan, Wilmen, Andreas, Wang, Dongli, Wang, Xinquan, Bauzon, Maxine, Kim, Ji-Yun, Linden, Lars, Li, Liang, Egner, Ursula, Marquardt, Tobias, Moosmayer, Dieter, Tebbe, Jan, Glück, Julian Marius, Ellinger, Philipp, McLean, Kirk, Yuan, Shujun, Yegneswaran, Subramanian, Jiang, Xiaoqiao, Evans, Vince, Gu, Jian-Ming, Schneider, Doug, Zhu, Ying, Xu, Yifan, Mallari, Cornell, Hesslein, Ashley, Wang, Yan, Schmidt, Nicole, Gutberlet, Katrin, Ruehl-Fehlert, Christine, Freyberger, Alexius, Hermiston, Terry, Patel, Chandra, Sim, Derek, Mosnier, Laurent O., Laux, Volker
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Journal Article
Mechanistic Modeling of the Pharmacodynamic and Pharmacokinetic Relationship of Tissue Factor Pathway Inhibitor-Neutralizing Antibody (BAY 1093884) in Cynomolgus Monkeys
Gu, Jian-Ming, Zhao, Xiao-Yan, Schwarz, Thomas, Schuhmacher, Joachim, Baumann, Andreas, Ho, Elena, Subramanyan, Babu, Tran, Kathy, Myles, Timothy, Patel, Chandra, Koellnberger, Maria
Published in The AAPS journal (01.07.2017)
Published in The AAPS journal (01.07.2017)
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Journal Article
A new polymorph of the gastrokinetic drug cisapride monohydrate
Zhou, Xin Bo, Zhu, Jian Rong, Gu, Jian Ming, Hu, Xiu Rong
Published in Acta crystallographica. Section C, Crystal structure communications (01.06.2018)
Published in Acta crystallographica. Section C, Crystal structure communications (01.06.2018)
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Journal Article
Crystal structure of febuxostat-acetic acid (1/1)
Wu, Min, Hu, Xiu-Rong, Gu, Jian-Ming, Tang, Gu-Ping
Published in Acta crystallographica. Section E, Crystallographic communications (01.05.2015)
Published in Acta crystallographica. Section E, Crystallographic communications (01.05.2015)
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Journal Article
Lipid presentation by the protein C receptor links coagulation with autoimmunity
Müller-Calleja, Nadine, Hollerbach, Anne, Royce, Jennifer, Ritter, Svenja, Pedrosa, Denise, Madhusudhan, Thati, Teifel, Sina, Meineck, Myriam, Häuser, Friederike, Canisius, Antje, Nguyen, T Son, Braun, Johannes, Bruns, Kai, Etzold, Anna, Zechner, Ulrich, Strand, Susanne, Radsak, Markus, Strand, Dennis, Gu, Jian-Ming, Weinmann-Menke, Julia, Esmon, Charles T, Teyton, Luc, Lackner, Karl J, Ruf, Wolfram
Published in Science (American Association for the Advancement of Science) (12.03.2021)
Published in Science (American Association for the Advancement of Science) (12.03.2021)
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Journal Article
Crystal structure of vilazodone hydrochloride methanol monosolvate
Hu, Xiu-Rong, Ye, Jia-Li, Gu, Jian-Ming
Published in Acta crystallographica. Section E, Crystallographic communications (01.12.2016)
Published in Acta crystallographica. Section E, Crystallographic communications (01.12.2016)
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Journal Article
Disruption of the Endothelial Cell Protein C Receptor Gene in Mice Causes Placental Thrombosis and Early Embryonic Lethality
Gu, Jian-Ming, Crawley, James T B, Ferrell, Gary, Zhang, Fangjiu, Li, Weihong, Esmon, Naomi L, Esmon, Charles T
Published in The Journal of biological chemistry (08.11.2002)
Published in The Journal of biological chemistry (08.11.2002)
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Journal Article
Crystal structure of canagliflozin hemihydrate
Liu, Kai-Hang, Gu, Jian-Ming, Hu, Xiu-Rong, Tang, Gu-Ping
Published in Acta crystallographica. Section E, Crystallographic communications (01.05.2016)
Published in Acta crystallographica. Section E, Crystallographic communications (01.05.2016)
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Journal Article
Potent Triazolothione Inhibitor of Heat-Shock Protein-90
Feldman, Richard I, Mintzer, Bob, Zhu, Daguang, Wu, James M, Biroc, Sandra L, Yuan, Shendong, Emayan, Kumar, Chang, Zheng, Chen, Deborah, Arnaiz, Damian O, Bryant, Judi, Ge, Xue Snow, Whitlow, Marc, Adler, Marc, Polokoff, Mark A, Li, Wei-Wei, Ferrer, Mike, Sato, Takashi, Gu, Jian-Ming, Shen, Jun, Tseng, Jih-Lie, Dinter, Harald, Buckman, Brad
Published in Chemical biology & drug design (01.07.2009)
Published in Chemical biology & drug design (01.07.2009)
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Journal Article
Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment
Mei, Baisong, Pan, Clark, Jiang, Haiyan, Tjandra, Hendri, Strauss, Jonathan, Chen, Yaoqi, Liu, Tongyao, Zhang, Xin, Severs, Joanne, Newgren, Jim, Chen, Jianmin, Gu, Jian-Ming, Subramanyam, Babu, Fournel, Michael A., Pierce, Glenn F., Murphy, John E.
Published in Blood (15.07.2010)
Published in Blood (15.07.2010)
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Journal Article
Crystal structures of vortioxetine and its methanol monosolvate
Zhou, Xin-Bo, Gu, Jian-Ming, Sun, Meng-Ying, Hu, Xiu-Rong, Wu, Su-Xiang
Published in Acta crystallographica. Section E, Crystallographic communications (01.08.2015)
Published in Acta crystallographica. Section E, Crystallographic communications (01.08.2015)
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Journal Article
The Gradual Correction of Adult Severe Rigid Equinus Deformity Using Minimal Invasive U-Osteotomy With Taylor Spatial Frame
Du, Hui, He, Xiao-Tian, Yin, Xing-Hua, Gu, Jian-Ming, Zhou, Yi-Xin, Yang, Jing, Wu, Yong
Published in Foot & ankle international (01.01.2023)
Published in Foot & ankle international (01.01.2023)
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Journal Article
Marbofloxacin
Shen, Jin, Qian, Jing-Jing, Gu, Jian-Ming, Hu, Xiu-Rong
Published in Acta crystallographica. Section E, Structure reports online (01.04.2012)
Published in Acta crystallographica. Section E, Structure reports online (01.04.2012)
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Journal Article
Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice
Gu, Jian-Ming, Johns, Anthony, Morser, John, Dole, William P., Greaves, David R., Deng, Gary G.
Published in Journal of cellular physiology (01.07.2005)
Published in Journal of cellular physiology (01.07.2005)
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Journal Article
Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease
Gu, Jian-Ming, Yuan, Shujun, Sim, Derek, Abe, Keith, Liu, Perry, Rosenbruch, Martin, Bringmann, Peter, Kauser, Katalin
Published in Experimental hematology (01.04.2018)
Published in Experimental hematology (01.04.2018)
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Journal Article
Moxifloxacinium chloride monohydrate
Qian, Jing-Jing, Gu, Jian-Ming, Shen, Jin, Hu, Xiu-Rong, Wu, Su-Xiang
Published in Acta crystallographica. Section E, Structure reports online (01.10.2011)
Published in Acta crystallographica. Section E, Structure reports online (01.10.2011)
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Journal Article
Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth
Kiewlich, David, Zhang, Jianhuan, Gross, Cynthia, Xia, Wei, Larsen, Brent, Cobb, Ronald R., Biroc, Sandra, Gu, Jian-Ming, Sato, Takashi, Light, David R., Heitner, Tara, Willuda, Joerg, Vogel, David, Monteclaro, Felipe, Citkowicz, Andrzej, Roffler, Steve R., Zajchowski, Deborah A.
Published in Neoplasia (New York, N.Y.) (01.01.2006)
Published in Neoplasia (New York, N.Y.) (01.01.2006)
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Journal Article