Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children
Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, L. G., Morgan, N. G., Mandrup-Poulsen, T.
Published in Diabetologia (01.09.2012)
Published in Diabetologia (01.09.2012)
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Journal Article
Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
Lundh, M, Christensen, D. P, Rasmussen, D. N, Mascagni, P, Dinarello, C. A, Billestrup, N, Grunnet, L. G, Mandrup-Poulsen, T
Published in Diabetologia (01.12.2010)
Published in Diabetologia (01.12.2010)
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Journal Article
Leukocyte telomere length is associated with elevated plasma glucose and HbA1c in young healthy men independent of birth weight
Grunnet, L G, Pilgaard, K, Alibegovic, A, Jensen, C B, Hjort, L, Ozanne, S E, Bennett, M, Vaag, A, Brøns, C
Published in Scientific reports (21.05.2019)
Published in Scientific reports (21.05.2019)
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Journal Article
A common variation of the PTEN gene is associated with peripheral insulin resistance
Grinder-Hansen, L, Ribel-Madsen, R, Wojtaszewski, J.F.P, Poulsen, P, Grunnet, L.G, Vaag, A
Published in Diabetes & metabolism (01.09.2016)
Published in Diabetes & metabolism (01.09.2016)
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Journal Article
Are hepatic and soleus lipid content, assessed by magnetic resonance spectroscopy, associated with low birth weight or insulin resistance in a rural Indian population of healthy young men?
Livingstone, R. S., Grunnet, L. G., Thomas, N., Eapen, A., Antonisamy, B., Mohan, V. R., Spurgeon, R., Frank, I. D., Bygbjerg, I. C., Vaag, A.
Published in Diabetic medicine (01.03.2016)
Published in Diabetic medicine (01.03.2016)
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Journal Article
Being born small-for-gestational-age is associated with an unfavourable dietary intake in Danish adolescent girls: findings from the Danish National Birth Cohort
Kampmann, F. B., Grunnet, L. G., Halldorsson, T. I., Bjerregaard, A. A., Granstrøm, C., Pires, S. M., Strøm, M., Vaag, A. A., Tetens, I., Olsen, S. F.
Published in Journal of developmental origins of health and disease (01.08.2019)
Published in Journal of developmental origins of health and disease (01.08.2019)
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Journal Article
Effects of an outdoor bicycle-based intervention in healthy rural Indian men with normal and low birth weight
Madsen, C., Mogensen, P., Thomas, N., Christensen, D. L., Bygbjerg, I. C., Mohan, V., Inbakumari, M., Nadig, S. V., Alex, R., Geetanjali, F. S., Westgate, K., Brage, S., Vaag, A., Grunnet, L. G.
Published in Journal of developmental origins of health and disease (01.02.2015)
Published in Journal of developmental origins of health and disease (01.02.2015)
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Journal Article
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus
Christensen, Dan P, Dahllöf, Mattias, Lundh, Morten, Rasmussen, Daniel N, Nielsen, Mette D, Billestrup, Nils, Grunnet, Lars G, Mandrup-Poulsen, Thomas
Published in Molecular medicine (Cambridge, Mass.) (01.05.2011)
Published in Molecular medicine (Cambridge, Mass.) (01.05.2011)
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Journal Article
Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines
Hansen, Jakob Bondo, Tonnesen, Morten Fog, Madsen, Andreas Nygaard, Hagedorn, Peter H., Friberg, Josefine, Grunnet, Lars Groth, Heller, R. Scott, Nielsen, Anja Østergren, Størling, Joachim, Baeyens, Luc, Anker-Kitai, Leeat, Qvortrup, Klaus, Bouwens, Luc, Efrat, Shimon, Aalund, Mogens, Andrews, Nancy C., Billestrup, Nils, Karlsen, Allan E., Holst, Birgitte, Pociot, Flemming, Mandrup-Poulsen, Thomas
Published in Cell metabolism (03.10.2012)
Published in Cell metabolism (03.10.2012)
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Journal Article
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding
Gillberg, Linn, Perfilyev, Alexander, Brøns, Charlotte, Thomasen, Martin, Grunnet, Louise G., Volkov, Petr, Rosqvist, Fredrik, Iggman, David, Dahlman, Ingrid, Risérus, Ulf, Rönn, Tina, Nilsson, Emma, Vaag, Allan, Ling, Charlotte
Published in Diabetologia (01.04.2016)
Published in Diabetologia (01.04.2016)
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Journal Article
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, Dan Ploug, Gysemans, Conny, Lundh, Morten, Dahllöf, Mattias Salling, Noesgaard, Daniel, Schmidt, Søren Fisker, Mandrup, Susanne, Birkbak, Nikolai, Workmand, Christopher T., Piemonti, Lorenzo, Blaabjerg, Lykke, Monzani, Valmen, Fossati, Gianluca, Mascagni, Paolo, Paraskevas, Steven, Aikin, Reid A., Billestrup, Nils, Grunnet, Lars Groth, Dinarello, Charles A., Mathieu, Chantal, Mandrup-Poulsen, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
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Journal Article
High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression
Fred, Rikard G, Bang-Berthelsen, Claus H, Mandrup-Poulsen, Thomas, Grunnet, Lars G, Welsh, Nils
Published in PloS one (26.05.2010)
Published in PloS one (26.05.2010)
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Journal Article
Altering β-cell number through stable alteration of miR-21 and miR-34a expression
Backe, Marie Balslev, Novotny, Guy Wayne, Christensen, Dan Ploug, Grunnet, Lars Groth, Mandrup-Poulsen, Thomas
Published in Islets (01.01.2014)
Published in Islets (01.01.2014)
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Journal Article
Some differences in the EEG of brain tumors and cerebral vascular accidents
Grunnet, G L, Goldensohn, E S
Published in Electroencephalography and clinical neurophysiology (01.11.1967)
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Published in Electroencephalography and clinical neurophysiology (01.11.1967)
Journal Article
The lysine deacetylase inhibitor Givinostat inhibits β-cell IL-1β induced IL-1β transcription and processing
Dahllof, MS, Christensen, DP, Lundh, M, Dinarello, CA, Mascagni, P, Grunnet, LG, Mandrup-Poulsen, T
Published in Islets (01.11.2012)
Published in Islets (01.11.2012)
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Journal Article
Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells
Tonnesen, Morten F, Grunnet, Lars G, Friberg, Josefine, Cardozo, Alessandra K, Billestrup, Nils, Eizirik, Décio L, Størling, Joachim, Mandrup-Poulsen, Thomas
Published in Endocrinology (Philadelphia) (01.09.2009)
Published in Endocrinology (Philadelphia) (01.09.2009)
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