Novel TIE‐2 inhibitor BAY‐826 displays in vivo efficacy in experimental syngeneic murine glioma models
Schneider, Hannah, Szabo, Emese, Machado, Raquel A. C., Broggini‐Tenzer, Angela, Walter, Alexander, Lobell, Mario, Heldmann, Dieter, Süssmeier, Frank, Grünewald, Sylvia, Weller, Michael
Published in Journal of neurochemistry (01.01.2017)
Published in Journal of neurochemistry (01.01.2017)
Get full text
Journal Article
Correction: Effects of regorafenib on the mononuclear/phagocyte system and how these contribute to the inhibition of colorectal tumors in mice
Grünewald, Sylvia, Stecklum, Maria, Rizzo, Manuel, Rathjens, Jonathan, Fiebig, Lukas, Zopf, Dieter
Published in European journal of medical research (24.06.2023)
Published in European journal of medical research (24.06.2023)
Get full text
Journal Article
Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance
Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea
Published in Molecular cancer therapeutics (01.11.2018)
Published in Molecular cancer therapeutics (01.11.2018)
Get full text
Journal Article
Monitoring regulated protein-protein interactions using split TEV
Laage, Rico, Rossner, Moritz J, Wehr, Michael C, Bolz, Ulrike, Fischer, Tobias M, Grünewald, Sylvia, Scheek, Sigrid, Bach, Alfred, Nave, Klaus-Armin
Published in Nature methods (01.12.2006)
Published in Nature methods (01.12.2006)
Get full text
Journal Article
Effects of regorafenib on the mononuclear/phagocyte system and how these contribute to the inhibition of colorectal tumors in mice
Grünewald, Sylvia, Stecklum, Maria, Rizzo, Manuel, Rathjens, Jonathan, Fiebig, Lukas, Zopf, Dieter
Published in European journal of medical research (03.04.2023)
Published in European journal of medical research (03.04.2023)
Get full text
Journal Article
Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
Sugawara, Tatsuo, Nevedomskaya, Ekaterina, Heller, Simon, Böhme, Annika, Lesche, Ralf, Ahsen, Oliver, Grünewald, Sylvia, Nguyen, Holly M., Corey, Eva, Baumgart, Simon J., Georgi, Victoria, Pütter, Vera, Fernández‐Montalván, Amaury, Vasta, James D., Robers, Matthew B., Politz, Oliver, Mumberg, Dominik, Haendler, Bernard
Published in Molecular oncology (01.03.2024)
Published in Molecular oncology (01.03.2024)
Get full text
Journal Article
Role of heteromer formation in GABA(B) receptor function
Kuner, Rohini, Kohr, Georg, Grunewald, Sylvia, Eisenhardt, Gisela
Published in Science (American Association for the Advancement of Science) (01.01.1999)
Published in Science (American Association for the Advancement of Science) (01.01.1999)
Get full text
Journal Article
Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4
Schneider, Armin, Laage, Rico, Von Ahsen, Oliver, Fischer, Achim, Rossner, Moritz, Scheek, Sigrid, Grünewald, Sylvia, Kuner, Rohini, Weber, Daniela, Krüger, Carola, Klaussner, Bettina, Götz, Bernhard, Hiemisch, Holger, Newrzella, Dieter, Martin‐Villalba, Ana, Bach, Alfred, Schwaninger, Markus
Published in Journal of neurochemistry (01.03.2004)
Published in Journal of neurochemistry (01.03.2004)
Get full text
Journal Article
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Vriens, Kim, Christen, Stefan, Parik, Sweta, Broekaert, Dorien, Yoshinaga, Kazuaki, Talebi, Ali, Dehairs, Jonas, Escalona-Noguero, Carmen, Schmieder, Roberta, Cornfield, Thomas, Charlton, Catriona, Romero-Pérez, Laura, Rossi, Matteo, Rinaldi, Gianmarco, Orth, Martin F., Boon, Ruben, Kerstens, Axelle, Kwan, Suet Ying, Faubert, Brandon, Méndez-Lucas, Andrés, Kopitz, Charlotte C., Chen, Ting, Fernandez-Garcia, Juan, Duarte, João A. G., Schmitz, Arndt A., Steigemann, Patrick, Najimi, Mustapha, Hägebarth, Andrea, Van Ginderachter, Jo A., Sokal, Etienne, Gotoh, Naohiro, Wong, Kwok-Kin, Verfaillie, Catherine, Derua, Rita, Munck, Sebastian, Yuneva, Mariia, Beretta, Laura, DeBerardinis, Ralph J., Swinnen, Johannes V., Hodson, Leanne, Cassiman, David, Verslype, Chris, Christian, Sven, Grünewald, Sylvia, Grünewald, Thomas G. P., Fendt, Sarah-Maria
Published in Nature (London) (01.02.2019)
Published in Nature (London) (01.02.2019)
Get full text
Journal Article
Rogaratinib: A potent and selective pan‐FGFR inhibitor with broad antitumor activity in FGFR‐overexpressing preclinical cancer models
Grünewald, Sylvia, Politz, Oliver, Bender, Sebastian, Héroult, Mélanie, Lustig, Klemens, Thuss, Uwe, Kneip, Christoph, Kopitz, Charlotte, Zopf, Dieter, Collin, Marie‐Pierre, Boemer, Ulf, Ince, Stuart, Ellinghaus, Peter, Mumberg, Dominik, Hess‐Stumpp, Holger, Ziegelbauer, Karl
Published in International journal of cancer (01.09.2019)
Published in International journal of cancer (01.09.2019)
Get full text
Journal Article
Expression of Calnexin Reflects Paneth Cell Differentiation and Function
Gassler, Nikolaus, Schnölzer, Martina, Rohr, Claudia, Helmke, Burkhard, Kartenbeck, Jürgen, Grünewald, Sylvia, Laage, Rico, Schneider, Armin, Kränzlin, Bettina, Bach, Alfred, Otto, Herwart F, Autschbach, Frank
Published in Laboratory investigation (01.12.2002)
Published in Laboratory investigation (01.12.2002)
Get full text
Journal Article
Abstract 5036: Correlation of preclinical antitumor activity of regorafenib in CRC-PDX xenografts with gene expression and clinical parameters of the primary tumor
Seidel, Henrik, Hoffmann, Jens, Lesche, Ralf, Grünewald, Sylvia, Henderson, David, Zopf, Dieter
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor
Collin, Marie‐Pierre, Lobell, Mario, Hübsch, Walter, Brohm, Dirk, Schirok, Hartmut, Jautelat, Rolf, Lustig, Klemens, Bömer, Ulf, Vöhringer, Verena, Héroult, Mélanie, Grünewald, Sylvia, Hess‐Stumpp, Holger
Published in ChemMedChem (06.03.2018)
Published in ChemMedChem (06.03.2018)
Get full text
Journal Article
Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids
Barbier, Michaël, Jaensch, Steffen, Cornelissen, Frans, Vidic, Suzana, Gjerde, Kjersti, de Hoogt, Ronald, Graeser, Ralph, Gustin, Emmanuel, Chong, Yolanda T
Published in PloS one (01.06.2016)
Published in PloS one (01.06.2016)
Get full text
Journal Article
COMBINATION OF ATR KINASE INHIBITORS WITH 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE COMPOUNDS
SIEMEISTER, GERHARD, HAENDLER, BERNARD, LIU, NINGSHU, WENGNER, ANTJE MARGRET, GRUNEWALD, SYLVIA
Year of Publication 23.04.2020
Get full text
Year of Publication 23.04.2020
Patent