Targeting Cathepsin C in PR3-ANCA Vasculitis
Jerke, Uwe, Eulenberg-Gustavus, Claudia, Rousselle, Anthony, Nicklin, Paul, Kreideweiss, Stefan, Grundl, Marc A, Eickholz, Peter, Nickles, Katrin, Schreiber, Adrian, Korkmaz, Brice, Kettritz, Ralph
Published in Journal of the American Society of Nephrology (01.05.2022)
Published in Journal of the American Society of Nephrology (01.05.2022)
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Interleukin‐1 receptor‐associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll‐like receptors 4 and 7/8 in murine and human lungs
Sayers, Ian, Thakker, Dhruma, Billington, Charlotte, Kreideweiss, Stefan, Grundl, Marc A., Bouyssou, Thierry, Thamm, Sven, Kreuz, Sebastian, Hall, Ian P.
Published in British journal of pharmacology (01.11.2024)
Published in British journal of pharmacology (01.11.2024)
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BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity
Palazzesi, Ferruccio, Hermann, Markus R, Grundl, Marc A, Pautsch, Alexander, Seeliger, Daniel, Tautermann, Christofer S, Weber, Alexander
Published in Journal of chemical information and modeling (22.06.2020)
Published in Journal of chemical information and modeling (22.06.2020)
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Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats
Liu, Baoer, Korkmaz, Brice, Kraft, Patricia, Mayer, Tobias, Sayour, Alex A, Grundl, Marc A, Domain, Roxane, Karck, Matthias, Szabó, Gábor, Korkmaz-Icöz, Sevil
Published in Journal of translational medicine (09.11.2023)
Published in Journal of translational medicine (09.11.2023)
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Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1
Custódio, Tânia F., Killer, Maxime, Yu, Dingquan, Puente, Virginia, Teufel, Daniel P., Pautsch, Alexander, Schnapp, Gisela, Grundl, Marc, Kosinski, Jan, Löw, Christian
Published in Nature communications (14.09.2023)
Published in Nature communications (14.09.2023)
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opnMe.com: a digital initiative for sharing tools with the biomedical research community
Gollner, Andreas, Köster, Markus, Nicklin, Paul, Trieselmann, Thomas, Klein, Elliott, Vlach, Jaromir, Heine, Claudia, Grundl, Marc, Ramharter, Jürgen, Wyatt, David, Chaturvedi, Menorca, Ciulli, Alessio, Carter, Katharine C., Müller, Susanne, Bischoff, Daniel, Ettmayer, Peter, Haaksma, Eric, Mack, Jürgen, McConnell, Darryl, Stenkamp, Dirk, Weinstabl, Harald, Zentgraf, Matthias, Wood, Clive R., Montel, Florian
Published in Nature reviews. Drug discovery (01.07.2022)
Published in Nature reviews. Drug discovery (01.07.2022)
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BIreactive: Expanding the Scope of Reactivity Predictions to Propynamides
Hermann, Markus R, Tautermann, Christofer S, Sieger, Peter, Grundl, Marc A, Weber, Alexander
Published in Pharmaceuticals (Basel, Switzerland) (12.01.2023)
Published in Pharmaceuticals (Basel, Switzerland) (12.01.2023)
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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule
Tautermann, Christofer S, Binder, Florian, Büttner, Frank H, Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A, Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Mack, Volker, Montel, Florian, Peters, Stefan, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Schnapp, Gisela, Thamm, Sven, Zeeb, Markus
Published in Journal of medicinal chemistry (10.01.2019)
Published in Journal of medicinal chemistry (10.01.2019)
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An Intermolecular Base Triple as the Basis of Ligand Specificity and Affinity in the Guanine- and Adenine-Sensing Riboswitch RNAs
Noeske, Jonas, Richter, Christian, Grundl, Marc A., Nasiri, Hamid R., Schwalbe, Harald, Wöhnert, Jens, Wüthrich, Kurt
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
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Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
Rosenbrock, Holger, Kramer, Gert, Hobson, Scott, Koros, Eliza, Grundl, Marc, Grauert, Matthias, Reymann, Klaus G., Schröder, Ulrich H.
Published in European journal of pharmacology (10.08.2010)
Published in European journal of pharmacology (10.08.2010)
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Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: Insights from a receptor model
Kriegl, Jan M., Martyres, Domnic, Grundl, Marc A., Anderskewitz, Ralf, Dollinger, Horst, Rast, Georg, Schmid, Bernhard, Seither, Peter, Tautermann, Christofer S.
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
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Development of a Friedel−Crafts Triflation
Grundl, Marc A, Kaster, Anne, Beaulieu, Ellen D, Trauner, Dirk
Published in Organic letters (23.11.2006)
Published in Organic letters (23.11.2006)
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Bioconjugates of Enantiomerically Pure Organopalladium Compounds by Metal-Assisted Positional Selective Transesterifications at Palladium Enolates
Hashmi, A. Stephen K., Riedel, Dominic, Grundl, Marc A., Wittel, Bärbel C., Föll, Andreas, Lubkoll, Jana, Traut, Telisha, Hewer, Raymond, Rominger, Frank, Frey, Wolfgang, Bats, Jan W.
Published in Chemistry : a European journal (27.05.2011)
Published in Chemistry : a European journal (27.05.2011)
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Photochemical Synthesis of Prochiral Dialkyl 3,3-Dialkylcyclopropene-1,2-dicarboxylates with Facial Shielding Substituents and Related Substrates
Hashmi, A. Stephen K., Grundl, Marc A., Nass, Andreas Rivas, Naumann, Frank, Bats, Jan W., Bolte, Michael
Published in European journal of organic chemistry (01.12.2001)
Published in European journal of organic chemistry (01.12.2001)
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