The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex
Capell, A, Grünberg, J, Pesold, B, Diehlmann, A, Citron, M, Nixon, R, Beyreuther, K, Selkoe, D J, Haass, C
Published in The Journal of biological chemistry (06.02.1998)
Published in The Journal of biological chemistry (06.02.1998)
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The Presenilin 2 Mutation (N141I) Linked to Familial Alzheimer Disease (Volga German Families) Increases the Secretion of Amyloid β Protein Ending at the 42nd (or 43rd) Residue
Tomita, Taisuke, Maruyama, Kei, Saido, Takaomi C., Kume, Hideaki, Shinozaki, Kohki, Tokuhiro, Shinya, Capell, Anja, Walter, Jochen, Grünberg, Jürgen, Haass, Christian, Iwatsubo, Takeshi, Obata, Kunihiko
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
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Zebrafish (Danio rerio) Presenilin Promotes Aberrant Amyloid β-Peptide Production and Requires a Critical Aspartate Residue for Its Function in Amyloidogenesis
Leimer, Uwe, Lun, Klaus, Romig, Helmut, Walter, Jochen, Grünberg, Jürgen, Brand, Michael, Haass, Christian
Published in Biochemistry (Easton) (12.10.1999)
Published in Biochemistry (Easton) (12.10.1999)
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High-Yield Production of Recombinant Antibody Fragments in HEK-293 Cells Using Sodium Butyrate
Grünberg, Jürgen, Knogler, Karin, Waibel, Robert, Novak-Hofer, Ilse
Published in BioTechniques (01.05.2003)
Published in BioTechniques (01.05.2003)
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The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
Walter, J, Capell, A, Grünberg, J, Pesold, B, Schindzielorz, A, Prior, R, Podlisny, M B, Fraser, P, Hyslop, P S, Selkoe, D J, Haass, C
Published in Molecular medicine (Cambridge, Mass.) (01.11.1996)
Published in Molecular medicine (Cambridge, Mass.) (01.11.1996)
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Caspase-mediated cleavage is not required for the activity of presenilins in amyloidogenesis and NOTCH signaling
Brockhaus, M, Grünberg, J, Röhrig, S, Loetscher, H, Wittenburg, N, Baumeister, R, Jacobsen, H, Haass, C
Published in Neuroreport (11.05.1998)
Published in Neuroreport (11.05.1998)
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Cellular Expression and Proteolytic Processing of Presenilin Proteins Is Developmentally Regulated During Neuronal Differentiation
Capell, Anja, Saffrich, Rainer, Olivo, Jean‐Christophe, Meyn, Liane, Walter, Jochen, Grünberg, Jürgen, Mathews, Paul, Nixon, Ralph, Dotti, Carlos, Haass, Christian
Published in Journal of neurochemistry (01.12.1997)
Published in Journal of neurochemistry (01.12.1997)
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Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies
Diehlmann, Anke, Ida, Nobuo, Weggen, Sascha, Grünberg, Jürgen, Haass, Christian, Masters, Colin L., Bayer, Thomas A., Beyreuther, Konrad
Published in Journal of neuroscience research (15.05.1999)
Published in Journal of neuroscience research (15.05.1999)
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Proteolytic Processing of Human Lactase-Phlorizin Hydrolase Is a Two-Step Event: Identification of the Cleavage Sites
Wüthrich, Marcel, Grünberg, Jürgen, Hahn, Dagmar, Jacob, Ralf, Radebach, Ilona, Naim, Hassan Y., Sterchi, Erwin E.
Published in Archives of biochemistry and biophysics (01.12.1996)
Published in Archives of biochemistry and biophysics (01.12.1996)
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Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment
ARIT, Matthias J. E, NOVAK-HOFER, Ilse, GAST, Daniela, GSCHWEND, Verena, MOLDENHAUER, Gerhard, GRÜNBERG, Jurgen, HONER, Michael, SCHUBIGER, P. August, ALTEVOGT, Peter, KRUGER, Achim
Published in Cancer research (Chicago, Ill.) (15.01.2006)
Published in Cancer research (Chicago, Ill.) (15.01.2006)
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