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A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow
Mossu, Adrien, Rosito, Maria, Khire, Tejas, Li Chung, Hung, Nishihara, Hideaki, Gruber, Isabelle, Luke, Emma, Dehouck, Lucie, Sallusto, Federica, Gosselet, Fabien, McGrath, James L, Engelhardt, Britta
Published in Journal of cerebral blood flow and metabolism (01.03.2019)
Published in Journal of cerebral blood flow and metabolism (01.03.2019)
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Postarrest stalling rather than crawling favors CD8+ over CD4+ T‐cell migration across the blood–brain barrier under flow in vitro
Rudolph, Henriette, Klopstein, Armelle, Gruber, Isabelle, Blatti, Claudia, Lyck, Ruth, Engelhardt, Britta
Published in European journal of immunology (01.09.2016)
Published in European journal of immunology (01.09.2016)
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Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier
Castro Dias, Mariana, Odriozola Quesada, Adolfo, Soldati, Sasha, Bösch, Fabio, Gruber, Isabelle, Hildbrand, Tobias, Sönmez, Derya, Khire, Tejas, Witz, Guillaume, McGrath, James L., Piontek, Jörg, Kondoh, Masuo, Deutsch, Urban, Zuber, Benoît, Engelhardt, Britta
Published in Journal of cell science (15.04.2021)
Published in Journal of cell science (15.04.2021)
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T Cell‐Mediated Transport of Polymer Nanoparticles across the Blood–Brain Barrier
Ayer, Maxime, Schuster, Markus, Gruber, Isabelle, Blatti, Claudia, Kaba, Elisa, Enzmann, Gaby, Burri, Olivier, Guiet, Romain, Seitz, Arne, Engelhardt, Britta, Klok, Harm‐Anton
Published in Advanced healthcare materials (01.01.2021)
Published in Advanced healthcare materials (01.01.2021)
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ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro
Marchetti, Luca, Francisco, David, Soldati, Sasha, Haghayegh Jahromi, Neda, Barcos, Sara, Gruber, Isabelle, Pareja, Javier R., Thiriot, Aude, Andrian, Ulrich, Deutsch, Urban, Lyck, Ruth, Bruggmann, Rémy, Engelhardt, Britta
Published in European journal of immunology (01.01.2022)
Published in European journal of immunology (01.01.2022)
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Integrated Preclinical Data Analysis of ISB 2001 Enables Optimal Starting Dose Selection for a First-in-Class Trispecific T Cell Engager Phase1 Study in Multiple Myeloma
Drake, Adam, Pihlgren, Maria, Menon, Vinu, Pais, Daniela, Carretero-Iglesia, Laura, Berret, Jeremy, Hall, Olivia, Macoin, Julie, Gruber, Isabelle, Stainnack, Elodie, Estoppey, Carole, Dreyfus, Cyrille, Gudi, Girish, Matsuura, Tomomi, van der Graft, Piet H, Dyson, Michael, Konto, Cyril, Pacaud, Lida, Srivastava, Ankita, Zhukovsky, Eugene, Perro, Mario
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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ISB 2001, a First-in-Class Trispecific BCMA and CD38 T Cell Engager Designed to Overcome Mechanisms of Escape from Treatments for Multiple Myeloma By Targeting Two Antigens
Pihlgren, Maria, Hall, Olivia, Carretero, Laura, Estoppey, Carole, Drake, Adam, Pais, Daniela, Loyau, Jeremy, Berret, Jeremy, Gruber, Isabelle, Suere, Perrine, Schnorhk, Vincent, Nallet, Emilie, Pouleau, Blandine, Chimen, Myriam, Macoin, Julie, Stainnack, Elodie, Monney, Thierry, Delachat, Aurore, Dreyfus, Cyrille, Matthes, Thomas, Konto, Cyril, Dyson, Michael, Blein, Stanislas, Mbow, Lamine, Wood, Rebecca, Srivastava, Ankita, Zhukovsky, Eugene, Perro, Mario
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ
Rath, Jan A, Bajwa, Gagan, Carreres, Benoit, Gruber, Isabelle, Hoyer, Elisabeth, Wu, Meng-Fen, Yu, Yi-Ru, Ho, Ping-Chih, Brenner, Malcolm K., Gfeller, David, Arber, Caroline
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Postarrest stalling rather than crawling favors CD8 super(+) over CD4 super(+) T-cell migration across the blood-brain barrier under flow in vitro
Rudolph, Henriette, Klopstein, Armelle, Gruber, Isabelle, Blatti, Claudia, Lyck, Ruth, Engelhardt, Britta
Published in European journal of immunology (01.09.2016)
Published in European journal of immunology (01.09.2016)
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ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells
Carretero-Iglesia, Laura, Hall, Olivia J., Berret, Jérémy, Pais, Daniela, Estoppey, Carole, Chimen, Myriam, Monney, Thierry, Loyau, Jeremy, Dreyfus, Cyrille, Macoin, Julie, Perez, Cynthia, Menon, Vinu, Gruber, Isabelle, Laurendon, Amélie, Caro, Lydia N., Gudi, Girish S., Matsuura, Tomomi, van der Graaf, Piet H., Blein, Stanislas, Mbow, M. Lamine, Croasdale-Wood, Rebecca, Srivastava, Ankita, Dyson, Michael R., Matthes, Thomas, Kaya, Zeynep, Edwards, Claire M., Edwards, James R., Maiga, Sophie, Pellat-Deceunynck, Catherine, Touzeau, Cyrille, Moreau, Philippe, Konto, Cyril, Drake, Adam, Zhukovsky, Eugene A., Perro, Mario, Pihlgren, Maria
Published in Nature cancer (01.10.2024)
Published in Nature cancer (01.10.2024)
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Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4 + T cells
Rath, Jan A., Bajwa, Gagan, Carreres, Benoit, Hoyer, Elisabeth, Gruber, Isabelle, Martínez-Paniagua, Melisa A., Yu, Yi-Ru, Nouraee, Nazila, Sadeghi, Fatemeh, Wu, Mengfen, Wang, Tao, Hebeisen, Michael, Rufer, Nathalie, Varadarajan, Navin, Ho, Ping-Chih, Brenner, Malcolm K., Gfeller, David, Arber, Caroline
Published in Science advances (01.07.2020)
Published in Science advances (01.07.2020)
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