A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
Kreye, Jakob, Reincke, S. Momsen, Kornau, Hans-Christian, Sánchez-Sendin, Elisa, Corman, Victor Max, Liu, Hejun, Yuan, Meng, Wu, Nicholas C., Zhu, Xueyong, Lee, Chang-Chun D., Trimpert, Jakob, Höltje, Markus, Dietert, Kristina, Stöffler, Laura, von Wardenburg, Niels, van Hoof, Scott, Homeyer, Marie A., Hoffmann, Julius, Abdelgawad, Azza, Gruber, Achim D., Bertzbach, Luca D., Vladimirova, Daria, Li, Lucie Y., Barthel, Paula Charlotte, Skriner, Karl, Hocke, Andreas C., Hippenstiel, Stefan, Witzenrath, Martin, Suttorp, Norbert, Kurth, Florian, Franke, Christiana, Endres, Matthias, Schmitz, Dietmar, Jeworowski, Lara Maria, Richter, Anja, Schmidt, Marie Luisa, Schwarz, Tatjana, Müller, Marcel Alexander, Drosten, Christian, Wendisch, Daniel, Sander, Leif E., Osterrieder, Nikolaus, Wilson, Ian A., Prüss, Harald
Published in Cell (12.11.2020)
Published in Cell (12.11.2020)
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Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters
Osterrieder, Nikolaus, Bertzbach, Luca D, Dietert, Kristina, Abdelgawad, Azza, Vladimirova, Daria, Kunec, Dusan, Hoffmann, Donata, Beer, Martin, Gruber, Achim D, Trimpert, Jakob
Published in Viruses (20.07.2020)
Published in Viruses (20.07.2020)
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Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke
Winek, Katarzyna, Engel, Odilo, Koduah, Priscilla, Heimesaat, Markus M, Fischer, André, Bereswill, Stefan, Dames, Claudia, Kershaw, Olivia, Gruber, Achim D, Curato, Caterina, Oyama, Naoki, Meisel, Christian, Meisel, Andreas, Dirnagl, Ulrich
Published in Stroke (1970) (01.05.2016)
Published in Stroke (1970) (01.05.2016)
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The Roborovski Dwarf Hamster Is A Highly Susceptible Model for a Rapid and Fatal Course of SARS-CoV-2 Infection
Trimpert, Jakob, Vladimirova, Daria, Dietert, Kristina, Abdelgawad, Azza, Kunec, Dusan, Dökel, Simon, Voss, Anne, Gruber, Achim D., Bertzbach, Luca D., Osterrieder, Nikolaus
Published in Cell Reports (08.12.2020)
Published in Cell Reports (08.12.2020)
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SARS‐CoV‐2 infection of Chinese hamsters (Cricetulus griseus) reproduces COVID‐19 pneumonia in a well‐established small animal model
Bertzbach, Luca D., Vladimirova, Daria, Dietert, Kristina, Abdelgawad, Azza, Gruber, Achim D., Osterrieder, Nikolaus, Trimpert, Jakob
Published in Transboundary and emerging diseases (01.05.2021)
Published in Transboundary and emerging diseases (01.05.2021)
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IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
Naujoks, Jan, Tabeling, Christoph, Dill, Brian D, Hoffmann, Christine, Brown, Andrew S, Kunze, Mareike, Kempa, Stefan, Peter, Andrea, Mollenkopf, Hans-Joachim, Dorhoi, Anca, Kershaw, Olivia, Gruber, Achim D, Sander, Leif E, Witzenrath, Martin, Herold, Susanne, Nerlich, Andreas, Hocke, Andreas C, van Driel, Ian, Suttorp, Norbert, Bedoui, Sammy, Hilbi, Hubert, Trost, Matthias, Opitz, Bastian
Published in PLoS pathogens (01.02.2016)
Published in PLoS pathogens (01.02.2016)
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Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia
Dietert, Kristina, Gutbier, Birgitt, Wienhold, Sandra M, Reppe, Katrin, Jiang, Xiaohui, Yao, Ling, Chaput, Catherine, Naujoks, Jan, Brack, Markus, Kupke, Alexandra, Peteranderl, Christin, Becker, Stephan, von Lachner, Carolin, Baal, Nelli, Slevogt, Hortense, Hocke, Andreas C, Witzenrath, Martin, Opitz, Bastian, Herold, Susanne, Hackstein, Holger, Sander, Leif E, Suttorp, Norbert, Gruber, Achim D
Published in PloS one (20.11.2017)
Published in PloS one (20.11.2017)
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Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitis
Yang, Ines, Eibach, Daniel, Kops, Friederike, Brenneke, Birgit, Woltemate, Sabrina, Schulze, Jessika, Bleich, André, Gruber, Achim D, Muthupalani, Sureshkumar, Fox, James G, Josenhans, Christine, Suerbaum, Sebastian
Published in PloS one (09.08.2013)
Published in PloS one (09.08.2013)
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Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia
Högner, Katrin, Wolff, Thorsten, Pleschka, Stephan, Plog, Stephanie, Gruber, Achim D, Kalinke, Ulrich, Walmrath, Hans-Dieter, Bodner, Johannes, Gattenlöhner, Stefan, Lewe-Schlosser, Peter, Matrosovich, Mikhail, Seeger, Werner, Lohmeyer, Juergen, Herold, Susanne
Published in PLoS pathogens (01.02.2013)
Published in PLoS pathogens (01.02.2013)
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An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission
Adler, Julia M., Martin Vidal, Ricardo, Langner, Christine, Vladimirova, Daria, Abdelgawad, Azza, Kunecova, Daniela, Lin, Xiaoyuan, Nouailles, Geraldine, Voss, Anne, Kunder, Sandra, Gruber, Achim D., Wu, Haibo, Osterrieder, Nikolaus, Kunec, Dusan, Trimpert, Jakob
Published in Nature communications (02.02.2024)
Published in Nature communications (02.02.2024)
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Extending the Host Range of Listeria monocytogenes by Rational Protein Design
Wollert, Thomas, Pasche, Bastian, Rochon, Maike, Deppenmeier, Stefanie, van den Heuvel, Joop, Gruber, Achim D., Heinz, Dirk W., Lengeling, Andreas, Schubert, Wolf-Dieter
Published in Cell (01.06.2007)
Published in Cell (01.06.2007)
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Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
Hönzke, Katja, Obermayer, Benedikt, Mache, Christin, Fathykova, Diana, Kessler, Mirjana, Dökel, Simon, Wyler, Emanuel, Baumgardt, Morris, Löwa, Anna, Hoffmann, Karen, Graff, Patrick, Schulze, Jessica, Mieth, Maren, Hellwig, Katharina, Demir, Zeynep, Biere, Barbara, Brunotte, Linda, Mecate-Zambrano, Angeles, Bushe, Judith, Dohmen, Melanie, Hinze, Christian, Elezkurtaj, Sefer, Tönnies, Mario, Bauer, Torsten T, Eggeling, Stephan, Tran, Hong-Linh, Schneider, Paul, Neudecker, Jens, Rückert, Jens C, Schmidt-Ott, Kai M, Busch, Jonas, Klauschen, Frederick, Horst, David, Radbruch, Helena, Radke, Josefine, Heppner, Frank, Corman, Victor M, Niemeyer, Daniela, Müller, Marcel A, Goffinet, Christine, Mothes, Ronja, Pascual-Reguant, Anna, Hauser, Anja Erika, Beule, Dieter, Landthaler, Markus, Ludwig, Stephan, Suttorp, Norbert, Witzenrath, Martin, Gruber, Achim D, Drosten, Christian, Sander, Leif-Erik, Wolff, Thorsten, Hippenstiel, Stefan, Hocke, Andreas C
Published in The European respiratory journal (01.12.2022)
Published in The European respiratory journal (01.12.2022)
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Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding
Trimpert, Jakob, Dietert, Kristina, Firsching, Theresa C., Ebert, Nadine, Thi Nhu Thao, Tran, Vladimirova, Daria, Kaufer, Susanne, Labroussaa, Fabien, Abdelgawad, Azza, Conradie, Andelé, Höfler, Thomas, Adler, Julia M., Bertzbach, Luca D., Jores, Joerg, Gruber, Achim D., Thiel, Volker, Osterrieder, Nikolaus, Kunec, Dusan
Published in Cell reports (Cambridge) (03.08.2021)
Published in Cell reports (Cambridge) (03.08.2021)
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Avian malaria deaths in parrots, Europe
Olias, Philipp, Wegelin, Maria, Zenker, Wolfgang, Freter, Sabrina, Gruber, Achim D, Klopfleisch, Robert
Published in Emerging infectious diseases (01.05.2011)
Published in Emerging infectious diseases (01.05.2011)
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Evolutionarily conserved properties of CLCA proteins 1, 3 and 4, as revealed by phylogenetic and biochemical studies in avian homologues
Bartenschlager, Florian, Klymiuk, Nikolai, Weise, Christoph, Kuropka, Benno, Gruber, Achim D, Mundhenk, Lars
Published in PloS one (13.04.2022)
Published in PloS one (13.04.2022)
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Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice
Lask, Aina, Gutbier, Birgitt, Kershaw, Olivia, Nouailles, Geraldine, Gruber, Achim D., Müller-Redetzky, Holger C., Chackowicz, Steven, Hamilton, Douglas A., Van Slyke, Paul, Witzenrath, Martin
Published in Scientific reports (15.09.2022)
Published in Scientific reports (15.09.2022)
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Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
Dogra, Tanya, Pelz, Lars, Boehme, Julia D., Kuechler, Jan, Kershaw, Olivia, Marichal-Gallardo, Pavel, Baelkner, Maike, Hein, Marc D., Gruber, Achim D., Benndorf, Dirk, Genzel, Yvonne, Bruder, Dunja, Kupke, Sascha Y., Reichl, Udo
Published in Scientific reports (28.11.2023)
Published in Scientific reports (28.11.2023)
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Identification of Antimotilins, Novel Inhibitors of Helicobacter pylori Flagellar Motility That Inhibit Stomach Colonization in a Mouse Model
Suerbaum, Sebastian, Coombs, Nina, Patel, Lubna, Pscheniza, Dimitri, Rox, Katharina, Falk, Christine, Gruber, Achim D, Kershaw, Olivia, Chhatwal, Patrick, Brönstrup, Mark, Bilitewski, Ursula, Josenhans, Christine
Published in mBio (26.04.2022)
Published in mBio (26.04.2022)
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