The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis
Chou, Chu-Fang, Hsieh, Yu-Hua, Grubbs, Clinton J., Atigadda, Venkatram R., Mobley, James A., Dummer, Reinhard, Muccio, Donald D., Eto, Isao, Elmets, Craig A., Garvey, W. Timothy, Chang, Pi-Ling
Published in Journal of dermatological science (01.06.2018)
Published in Journal of dermatological science (01.06.2018)
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Journal Article
Methyl Substitution of a Rexinoid Agonist Improves Potency and Reveals Site of Lipid Toxicity
Atigadda, Venkatram R, Xia, Gang, Desphande, Anil, Boerma, LeeAnn J, Lobo-Ruppert, Susan, Grubbs, Clinton J, Smith, Craig D, Brouillette, Wayne J, Muccio, Donald D
Published in Journal of medicinal chemistry (26.06.2014)
Published in Journal of medicinal chemistry (26.06.2014)
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Journal Article
Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention
Muccio, Donald D, Atigadda, Venkatram R, Brouillette, Wayne J, Bland, Kirby I, Krontiras, Helen, Grubbs, Clinton J
Published in Current topics in medicinal chemistry (01.01.2017)
Published in Current topics in medicinal chemistry (01.01.2017)
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Journal Article
Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene)
Vedell, Peter T, Lu, Yan, Grubbs, Clinton J, Yin, Yuxin, Jiang, Hui, Bland, Kirby I, Muccio, Donald D, Cvetkovic, Dusica, You, Ming, Lubet, Ronald
Published in Molecular pharmacology (01.03.2013)
Published in Molecular pharmacology (01.03.2013)
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Journal Article
Rosiglitazone, a PPAR gamma agonist: Potent promoter of hydroxybutyl(butyl)nitrosamine‐induced urinary bladder cancers
Lubet, Ronald A., Fischer, Susan M., Steele, Vernon E., Juliana, M. Margaret, Desmond, Renee', Grubbs, Clinton J.
Published in International journal of cancer (15.11.2008)
Published in International journal of cancer (15.11.2008)
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Journal Article
Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention
Desphande, Anil, Xia, Gang, Boerma, LeeAnn J., Vines, Kimberly K., Atigadda, Venkatram R., Lobo-Ruppert, Susan, Grubbs, Clinton J., Moeinpour, Fariba L., Smith, Craig D., Christov, Konstantin, Brouillette, Wayne J., Muccio, Donald D.
Published in Bioorganic & medicinal chemistry (01.01.2014)
Published in Bioorganic & medicinal chemistry (01.01.2014)
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Journal Article
Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models
Thompson, Matthew D, Grubbs, Clinton J, Bode, Ann M, Reid, Joel M, McGovern, Renee, Bernard, Philip S, Stijleman, Inge J, Green, Jeffrey E, Bennett, Christina, Juliana, M Margaret, Moeinpour, Fariba, Steele, Vernon E, Lubet, Ronald A
Published in Cancer prevention research (Philadelphia, Pa.) (01.03.2015)
Published in Cancer prevention research (Philadelphia, Pa.) (01.03.2015)
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Journal Article
Short-term Modulation of Cell Proliferation and Apoptosis and Preventive/Therapeutic Efficacy of Various Agents in a Mammary Cancer Model
Christov, Konstantin, Grubbs, Clinton J, Shilkaitis, Anne, Juliana, M Margaret, Lubet, Ronald A
Published in Clinical cancer research (15.09.2007)
Published in Clinical cancer research (15.09.2007)
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Journal Article
Preventive effects of Polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols
Lubet, Ronald A, Yang, Chung S, Lee, Mao-Jung, Hara, Yukihiko, Kapetanovic, Izet M, Crowell, James A, Steele, Vernon E, Juliana, M Margaret, Grubbs, Clinton J
Published in Molecular cancer therapeutics (01.07.2007)
Published in Molecular cancer therapeutics (01.07.2007)
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Journal Article
Gene Expression Profiling of Chemically Induced Rat Bladder Tumors
Yao, Ruisheng, Yi, Yijun, Grubbs, Clinton J., Lubet, Ronald A., You, Ming
Published in Neoplasia (New York, N.Y.) (01.03.2007)
Published in Neoplasia (New York, N.Y.) (01.03.2007)
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Journal Article
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes
Lubet, Ronald A, Szabo, Eva, Christov, Konstantin, Bode, Ann M, Ericson, Marna E, Steele, Vernon E, Juliana, M Margaret, Grubbs, Clinton J
Published in Molecular cancer therapeutics (01.04.2008)
Published in Molecular cancer therapeutics (01.04.2008)
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Journal Article
Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid
Jiang, Wen, Deng, Wentao, Bailey, Sarah, Nail, Clint D., Frost, Andra R., Brouillette, Wayne J., Muccio, Donald D., Grubbs, Clinton J., Lobo-ruppert, Susan M, Ruppert, J. Michael
Published in Cancer biology & therapy (01.02.2009)
Published in Cancer biology & therapy (01.02.2009)
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Journal Article
Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers
Atigadda, Venkatram R., Kashyap, Mahendra P., Yang, Zhengrong, Chattopadhyay, Debasish, Melo, Nathalia, Sinha, Rajesh, Belyaeva, Olga V., Chou, Chu-Fang, Chang, Pi-Ling, Kedishvili, Natalia Y., Grubbs, Clinton J., Renfrow, Matthew B., Muccio, Donald D., Elmets, Craig A., Athar, Mohammad
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Journal Article
Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide
Wang, Yian, Yao, Ruisheng, Maciag, Anna, Grubbs, Clinton J, Lubet, Ronald A, You, Ming
Published in Molecular cancer therapeutics (01.04.2006)
Published in Molecular cancer therapeutics (01.04.2006)
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Journal Article
Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers
Atigadda, Venkatram R., Xia, Gang, Deshpande, Anil, Wu, Lizhi, Kedishvili, Natalia, Smith, Craig D., Krontiras, Helen, Bland, Kirby I., Grubbs, Clinton J., Brouillette, Wayne J., Muccio, Donald D.
Published in Journal of medicinal chemistry (08.10.2015)
Published in Journal of medicinal chemistry (08.10.2015)
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Journal Article
Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K
KIM, Mi-Sung, KIM, Jong-Eun, DO YOUNG LIM, ZUNNAN HUANG, HANYONG CHEN, LANGFALD, Alyssa, LUBET, Ronald A, GRUBBS, Clinton J, ZIGANG DONG, BODE, Ann M
Published in Cancer prevention research (Philadelphia, Pa.) (01.02.2014)
Published in Cancer prevention research (Philadelphia, Pa.) (01.02.2014)
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Journal Article
Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression
Lubet, Ronald A, Steele, Vernon E, Shoemaker, Robert H, Grubbs, Clinton J
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2018)
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2018)
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