Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
Jiang, Xiaomo, Hao, Huai-Xiang, Growney, Joseph D., Woolfenden, Steve, Bottiglio, Cindy, Ng, Nicholas, Lu, Bo, Hsieh, Mindy H., Bagdasarian, Linda, Meyer, Ronald, Smith, Timothy R., Avello, Monika, Charlat, Olga, Xie, Yang, Porter, Jeffery A., Pan, Shifeng, Liu, Jun, McLaughlin, Margaret E., Cong, Feng
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Journal Article
IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism
GRASSIAN, Alexandra R, PARKER, Seth J, JOUD-CALDWELL, Carol, CHUNG, Franklin, HONG YIN, HANDLY, Erika D, STRAUB, Christopher, GROWNEY, Joseph D, HEIDEN, Matthew G. Vander, MURPHY, Anne N, PAGLIARINI, Raymond, METALLO, Christian M, DAVIDSON, Shawn M, DIVAKARUNI, Ajit S, GREEN, Courtney R, XIAMEI ZHANG, SLOCUM, Kelly L, MINYING PU, LIN, Fallon, VICKERS, Chad
Published in Cancer research (Chicago, Ill.) (15.06.2014)
Published in Cancer research (Chicago, Ill.) (15.06.2014)
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Journal Article
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
Zaugg, Kathrin, Yao, Yi, Reilly, Patrick T, Kannan, Karuppiah, Kiarash, Reza, Mason, Jacqueline, Huang, Ping, Sawyer, Suzanne K, Fuerth, Benjamin, Faubert, Brandon, Kalliomäki, Tuula, Elia, Andrew, Luo, Xunyi, Nadeem, Vincent, Bungard, David, Yalavarthi, Sireesha, Growney, Joseph D, Wakeham, Andrew, Moolani, Yasmin, Silvester, Jennifer, Ten, Annick You, Bakker, Walbert, Tsuchihara, Katsuya, Berger, Shelley L, Hill, Richard P, Jones, Russell G, Tsao, Ming, Robinson, Murray O, Thompson, Craig B, Pan, Guohua, Mak, Tak W
Published in Genes & development (15.05.2011)
Published in Genes & development (15.05.2011)
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Journal Article
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis
Tenen, Daniel G, Huang, Gang, Zhang, Pu, Hirai, Hideyo, Elf, Shannon, Yan, Xiaomei, Chen, Zhao, Koschmieder, Steffen, Okuno, Yutaka, Dayaram, Tajhal, Growney, Joseph D, Shivdasani, Ramesh A, Gilliland, D Gary, Speck, Nancy A, Nimer, Stephen D
Published in Nature genetics (01.01.2008)
Published in Nature genetics (01.01.2008)
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Journal Article
Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412
Growney, Joseph D., Clark, Jennifer J., Adelsperger, Jennifer, Stone, Richard, Fabbro, Doriano, Griffin, James D., Gilliland, D. Gary
Published in Blood (15.07.2005)
Published in Blood (15.07.2005)
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Journal Article
In Vivo Evaluation of Fibroblast Growth Factor Receptor Inhibition in Mouse Xenograft Models of Gastrointestinal Stromal Tumor
Schöffski, Patrick, Gebreyohannes, Yemarshet, Van Looy, Thomas, Manley, Paul, Growney, Joseph D, Squires, Matthew, Wozniak, Agnieszka
Published in Biomedicines (13.05.2022)
Published in Biomedicines (13.05.2022)
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Journal Article
Naip5 Affects Host Susceptibility to the Intracellular Pathogen Legionella pneumophila
Wright, Edward K., Goodart, Sheryl A., Growney, Joseph D., Hadinoto, Vey, Endrizzi, Matthew G., Long, E.Michelle, Sadigh, Keyvan, Abney, Andrew L., Bernstein-Hanley, Isaac, Dietrich, William F.
Published in Current biology (08.01.2003)
Published in Current biology (08.01.2003)
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Journal Article
Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages
Reddy, Anupama, Growney, Joseph D, Wilson, Nick S, Emery, Caroline M, Johnson, Jennifer A, Ward, Rebecca, Monaco, Kelli A, Korn, Joshua, Monahan, John E, Stump, Mark D, Mapa, Felipa A, Wilson, Christopher J, Steiger, Janine, Ledell, Jebediah, Rickles, Richard J, Myer, Vic E, Ettenberg, Seth A, Schlegel, Robert, Sellers, William R, Huet, Heather A, Lehár, Joseph
Published in PloS one (17.09.2015)
Published in PloS one (17.09.2015)
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Journal Article
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
Liu, Huayang, Golji, Javad, Brodeur, Lauren K, Chung, Franklin S, Chen, Julie T, deBeaumont, Rosalie S, Bullock, Caroline P, Jones, Michael D, Kerr, Grainne, Li, Li, Rakiec, Daniel P, Schlabach, Michael R, Sovath, Sosathya, Growney, Joseph D, Pagliarini, Raymond A, Ruddy, David A, MacIsaac, Kenzie D, Korn, Joshua M, McDonald, 3rd, E Robert
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Journal Article
Correction: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages
Reddy, Anupama, Growney, Joseph D, Wilson, Nick S, Emery, Caroline M, Johnson, Jennifer A, Ward, Rebecca, Monaco, Kelli A, Korn, Joshua, Monahan, John E, Stump, Mark D, Mapa, Felipa A, Wilson, Christopher J, Steiger, Janine, Ledell, Jebediah, Rickles, Richard J, Myer, Vic E, Ettenberg, Seth A, Schlegel, Robert, Sellers, William R, Huet, Heather A, Lehár, Joseph
Published in PloS one (05.01.2016)
Published in PloS one (05.01.2016)
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Journal Article
Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor
Cho, Young Shin, Levell, Julian R, Liu, Gang, Caferro, Thomas, Sutton, James, Shafer, Cynthia M, Costales, Abran, Manning, James R, Zhao, Qian, Sendzik, Martin, Shultz, Michael, Chenail, Gregg, Dooley, Julia, Villalba, Brian, Farsidjani, Ali, Chen, Jinyun, Kulathila, Raviraj, Xie, Xiaoling, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Heimbach, Tycho, Slocum, Kelly, Firestone, Brant, Pu, Minying, Pagliarini, Raymond, Growney, Joseph D
Published in ACS medicinal chemistry letters (12.10.2017)
Published in ACS medicinal chemistry letters (12.10.2017)
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Journal Article
Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T‐cell lymphoma models: Defining molecular mechanisms of resistance
Shao, Wenlin, Growney, Joseph D., Feng, Yun, O'Connor, Gregory, Pu, Minying, Zhu, Wenjing, Yao, Yung‐Mae, Kwon, Paul, Fawell, Stephen, Atadja, Peter
Published in International journal of cancer (01.11.2010)
Published in International journal of cancer (01.11.2010)
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Journal Article
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
Growney, Joseph D., Shigematsu, Hirokazu, Li, Zhe, Lee, Benjamin H., Adelsperger, Jennifer, Rowan, Rebecca, Curley, David P., Kutok, Jeffery L., Akashi, Koichi, Williams, Ifor R., Speck, Nancy A., Gilliland, D. Gary
Published in Blood (15.07.2005)
Published in Blood (15.07.2005)
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Journal Article
Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction
Huet, Heather A, Growney, Joseph D, Johnson, Jennifer A, Li, Jing, Bilic, Sanela, Ostrom, Lance, Zafari, Mohammad, Kowal, Colleen, Yang, Guizhi, Royo, Axelle, Jensen, Michael, Dombrecht, Bruno, Meerschaert, Kris R A, Kolkman, Joost A, Cromie, Karen D, Mosher, Rebecca, Gao, Hui, Schuller, Alwin, Isaacs, Randi, Sellers, William R, Ettenberg, Seth A
Published in mAbs (2014)
Published in mAbs (2014)
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Journal Article
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
Gotlib, Jason, Berubé, Caroline, Growney, Joseph D., Chen, Ching-Cheng, George, Tracy I., Williams, Christopher, Kajiguchi, Tomohiro, Ruan, Jia, Lilleberg, Stan L., Durocher, Jeffrey A., Lichy, Jack H., Wang, Yanfeng, Cohen, Pamela S., Arber, Daniel A., Heinrich, Michael C., Neckers, Len, Galli, Stephen J., Gilliland, D. Gary, Coutré, Steven E.
Published in Blood (15.10.2005)
Published in Blood (15.10.2005)
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Journal Article
Optimization of 3‑Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1
Levell, Julian R., Caferro, Thomas, Chenail, Gregg, Dix, Ina, Dooley, Julia, Firestone, Brant, Fortin, Pascal D., Giraldes, John, Gould, Ty, Growney, Joseph D., Jones, Michael D., Kulathila, Raviraj, Lin, Fallon, Liu, Gang, Mueller, Arne, van der Plas, Simon, Slocum, Kelly, Smith, Troy, Terranova, Remi, Touré, B. Barry, Tyagi, Viraj, Wagner, Trixie, Xie, Xiaoling, Xu, Ming, Yang, Fan S., Zhou, Liping X., Pagliarini, Raymond, Cho, Young Shin
Published in ACS medicinal chemistry letters (09.02.2017)
Published in ACS medicinal chemistry letters (09.02.2017)
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Journal Article
Optimization of the in Vitro Cardiac Safety of Hydroxamate-Based Histone Deacetylase Inhibitors
Shultz, Michael D, Cao, Xueying, Chen, Christine H, Cho, Young Shin, Davis, Nicole R, Eckman, Joe, Fan, Jianmei, Fekete, Alex, Firestone, Brant, Flynn, Julie, Green, Jack, Growney, Joseph D, Holmqvist, Mats, Hsu, Meier, Jansson, Daniel, Jiang, Lei, Kwon, Paul, Liu, Gang, Lombardo, Franco, Lu, Qiang, Majumdar, Dyuti, Meta, Christopher, Perez, Lawrence, Pu, Minying, Ramsey, Tim, Remiszewski, Stacy, Skolnik, Suzanne, Traebert, Martin, Urban, Laszlo, Uttamsingh, Vinita, Wang, Ping, Whitebread, Steven, Whitehead, Lewis, Yan-Neale, Yan, Yao, Yung-Mae, Zhou, Liping, Atadja, Peter
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Journal Article
P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT‐253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS
Schalm, Stefanie, Chutake, Yogesh, Breitkopf, Susanne, Mayo, Michele, Dumont, Nancy, Chen, Dapeng, Dixit, Vaishali, Karnik, Rahul, Mcdonald, Alice, Filiatrault, Jessica, Proctor, William, Qi, Frank, Hu, Kan‐Nian, Weiss, Matt, Gollerkeri, Ashwin, Sharma, Kirti, D Growney, Joseph, Williams, Juliet
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
The mouse Naip gene cluster on Chromosome 13 encodes several distinct functional transcripts
Huang, S, Scharf, J M, Growney, J D, Endrizzi, M G, Dietrich, W F
Published in Mammalian genome (01.10.1999)
Published in Mammalian genome (01.10.1999)
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