Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms TCF7L2 as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk
GROVES, Christopher J, ZEGGINI, Eleftheria, MCCARTHY, Mark I, MINTON, Jayne, FRAYLING, Timothy M, WEEDON, Michael N, RAYNER, Nigel W, HITMAN, Graham A, WALKER, Mark, WILTSHIRE, Steven, HATTERSLEY, Andrew T
Published in Diabetes (New York, N.Y.) (01.09.2006)
Published in Diabetes (New York, N.Y.) (01.09.2006)
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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction
Weedon, Michael N, McCarthy, Mark I, Hitman, Graham, Walker, Mark, Groves, Christopher J, Zeggini, Eleftheria, Rayner, N William, Shields, Beverley, Owen, Katharine R, Hattersley, Andrew T, Frayling, Timothy M
Published in PLoS medicine (01.10.2006)
Published in PLoS medicine (01.10.2006)
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Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth
FREATHY, Rachel M, BENNETT, Amanda J, PERRY, John R. B, POUTA, Anneli, RUOKONEN, Aimo, HYPPÖNEN, Elina, POWER, Chris, ELLIOTT, Paul, STRACHAN, David P, JÄRVELIN, Marjo-Riitta, SMITH, George Davey, MCCARTHY, Mark I, RING, Susan M, FRAYLING, Timothy M, HATTERSLEY, Andrew T, SHIELDS, Beverley, GROVES, Christopher J, TIMPSON, Nicholas J, WEEDON, Michael N, ZEGGINI, Eleftheria, LINDGREN, Cecilia M, LANGO, Hana
Published in Diabetes (New York, N.Y.) (01.06.2009)
Published in Diabetes (New York, N.Y.) (01.06.2009)
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Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets
Cauchi, Stéphane, Guerra, Silvia Del, Choquet, Hélène, D’Aleo, Valentina, Groves, Christopher J., Lupi, Roberto, McCarthy, Mark I., Froguel, Philippe, Marchetti, Piero
Published in Molecular genetics and metabolism (01.05.2010)
Published in Molecular genetics and metabolism (01.05.2010)
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Journal Article
Type 2 Diabetes TCF7L2 Risk Genotypes Alter Birth Weight: A Study of 24,053 Individuals
Freathy, Rachel M., Weedon, Michael N., Bennett, Amanda, Hyppönen, Elina, Relton, Caroline L., Knight, Beatrice, Shields, Beverley, Parnell, Kirstie S., Groves, Christopher J., Ring, Susan M., Pembrey, Marcus E., Ben-Shlomo, Yoav, Strachan, David P., Power, Chris, Jarvelin, Marjo-Riitta, McCarthy, Mark I., Davey Smith, George, Hattersley, Andrew T., Frayling, Timothy M.
Published in American journal of human genetics (01.06.2007)
Published in American journal of human genetics (01.06.2007)
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BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study
Louwers, Yvonne V, Rayner, Nigel W, Herrera, Blanca M, Stolk, Lisette, Groves, Christopher J, Barber, Thomas M, Uitterlinden, Andre G, Franks, Stephen, Laven, Joop S E, McCarthy, Mark I
Published in PloS one (31.01.2014)
Published in PloS one (31.01.2014)
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Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent
Hassanali, Neelam, De Silva, N Maneka G, Robertson, Neil, Rayner, N William, Barrett, Amy, Bennett, Amanda J, Groves, Christopher J, Matthews, David R, Katulanda, Prasad, Frayling, Timothy M, McCarthy, Mark I
Published in PloS one (13.06.2014)
Published in PloS one (13.06.2014)
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Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes
Boraska, Vesna, Rayner, Nigel W, Groves, Christopher J, Frayling, Timothy M, Diakite, Mahamadou, Rockett, Kirk A, Kwiatkowski, Dominic P, Day-Williams, Aaron G, McCarthy, Mark I, Zeggini, Eleftheria
Published in BMC genetics (06.05.2010)
Published in BMC genetics (06.05.2010)
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Performance and Stability of New Class of Fetal Bovine Sera (FBS) and Its Lyophilized Form in ELISpot and FluoroSpot Assays: Applications for Monitoring the Immune Response in Vaccine, and Cell and Gene Immunotherapy in Clinical Trials
Hosseini, Zhinous, Groves, Christopher J, Anders, Penny, Cave, Kristen, Krunkosky, Madelyn, Chappell, Brandi, Pattyn, Sofie, Davis, Devin, Janetzki, Sylvia, Reap, Elizabeth
Published in Methods in molecular biology (Clifton, N.J.) (2024)
Published in Methods in molecular biology (Clifton, N.J.) (2024)
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Baseline Plasma Cell Gene Signature Predicts Improvement in Systemic Sclerosis Skin Scores Following Treatment With Inebilizumab (MEDI‐551) and Correlates With Disease Activity in Systemic Lupus Erythematosus and Chronic Obstructive Pulmonary Disease
Streicher, Katie, Sridhar, Sriram, Kuziora, Mike, Morehouse, Christopher A., Higgs, Brandon W., Sebastian, Yinong, Groves, Christopher J., Pilataxi, Fernanda, Brohawn, Philip Z., Herbst, Ronald, Ranade, Koustubh
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2018)
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Prevalence and Morphology of Pouch and Ileal Adenomas in Familial Adenomatous Polyposis
Groves, Christopher J, Beveridge, Iain G, Swain, David J, Saunders, Brian P, Talbot, Ian C, Nicholls, John R, Phillips, Robin K
Published in Diseases of the colon & rectum (01.04.2005)
Published in Diseases of the colon & rectum (01.04.2005)
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Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells
Thomsen, Soren K., Raimondo, Anne, Hastoy, Benoit, Sengupta, Shahana, Dai, Xiao-Qing, Bautista, Austin, Censin, Jenny, Payne, Anthony J., Umapathysivam, Mahesh M., Spigelman, Aliya F., Barrett, Amy, Groves, Christopher J., Beer, Nicola L., Manning Fox, Jocelyn E., McCarthy, Mark I., Clark, Anne, Mahajan, Anubha, Rorsman, Patrik, MacDonald, Patrick E., Gloyn, Anna L.
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes
Juszczak, Agata, Pavić, Tamara, Vučković, Frano, Bennett, Amanda J, Shah, Neha, Pape Medvidović, Edita, Groves, Christopher J, Šekerija, Mario, Chandler, Kyla, Burrows, Carla, Rojnić Putarek, Nataša, Vučić Lovrenčić, Marijana, Ćuća Knežević, Jadranka, James, Tim J, Gloyn, Anna L, Lauc, Gordan, McCarthy, Mark I, Owen, Katharine R, Gornik, Olga
Published in Diabetes care (01.01.2019)
Published in Diabetes care (01.01.2019)
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Journal Article
Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes
Jafar-Mohammadi, Bahram, Groves, Christopher J, Owen, Katharine R, Frayling, Timothy M, Hattersley, Andrew T, McCarthy, Mark I, Gloyn, Anna L
Published in PloS one (12.08.2009)
Published in PloS one (12.08.2009)
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Significant Linkage of BMI to Chromosome 10p in the U.K. Population and Evaluation of GAD2 as a Positional Candidate
GROVES, Christopher J, ZEGGINI, Eleftheria, WALKER, Mark, HITMAN, Graham A, LEVY, Jonathan C, O'RAHILLY, Stephen, HATTERSLEY, Andrew T, MCCARTHY, Mark I, WILTSHIRE, Steven
Published in Diabetes (New York, N.Y.) (01.06.2006)
Published in Diabetes (New York, N.Y.) (01.06.2006)
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Is environmental radon gas associated with the incidence of neurodegenerative conditions? A retrospective study of multiple sclerosis in radon affected areas in England and Wales
Groves-Kirkby, Christopher J., Denman, Antony R., Campbell, Jackie, Crockett, Robin G.M., Phillips, Paul S., Rogers, Stephen
Published in Journal of environmental radioactivity (01.04.2016)
Published in Journal of environmental radioactivity (01.04.2016)
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Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24
WILTSHIRE, Steven, FRAYLING, Timothy M, MCCARTHY, Mark I, GROVES, Christopher J, LEVY, Jonathan C, HITMAN, Graham A, SAMPSON, Mike, WALKER, Mark, MENZEL, Stephan, HATTERSLEY, Andrew T, CARDON, Lon R
Published in Diabetes (New York, N.Y.) (01.03.2004)
Published in Diabetes (New York, N.Y.) (01.03.2004)
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Journal Article
The Plasma Cell Signature in Autoimmune Disease
Streicher, Katie, Morehouse, Christopher A., Groves, Christopher J., Rajan, Bhargavi, Pilataxi, Fernanda, Lehmann, Kim P., Brohawn, Philip Z., Higgs, Brandon W., McKeever, Kathleen, Greenberg, Steven A., Fiorentino, David, Richman, Laura K., Jallal, Bahija, Herbst, Ronald, Yao, Yihong, Ranade, Koustubh
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2014)
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