Increased Vulnerability to Ferroptosis in FUS-ALS
Ismail, Muhammad, Großmann, Dajana, Hermann, Andreas
Published in Biology (Basel, Switzerland) (01.04.2024)
Published in Biology (Basel, Switzerland) (01.04.2024)
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Journal Article
The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease
Grossmann, Dajana, Berenguer-Escuder, Clara, Chemla, Axel, Arena, Giuseppe, Krüger, Rejko
Published in Frontiers in neurology (15.09.2020)
Published in Frontiers in neurology (15.09.2020)
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Journal Article
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease
Boussaad, Ibrahim, Obermaier, Carolin D, Hanss, Zoé, Bobbili, Dheeraj R, Bolognin, Silvia, Glaab, Enrico, Wołyńska, Katarzyna, Weisschuh, Nicole, De Conti, Laura, May, Caroline, Giesert, Florian, Grossmann, Dajana, Lambert, Annika, Kirchen, Susanne, Biryukov, Maria, Burbulla, Lena F, Massart, Francois, Bohler, Jill, Cruciani, Gérald, Schmid, Benjamin, Kurz-Drexler, Annerose, May, Patrick, Duga, Stefano, Klein, Christine, Schwamborn, Jens C, Marcus, Katrin, Woitalla, Dirk, Vogt Weisenhorn, Daniela M, Wurst, Wolfgang, Baralle, Marco, Krainc, Dimitri, Gasser, Thomas, Wissinger, Bernd, Krüger, Rejko
Published in Science translational medicine (09.09.2020)
Published in Science translational medicine (09.09.2020)
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Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G > A (p.R272Q) or c.1348C > T (p.R450C) in the RHOT1 gene encoding Miro1
Chemla, Axel, Arena, Giuseppe, Onal, Gizem, Walter, Jonas, Berenguer-Escuder, Clara, Grossmann, Dajana, Grünewald, Anne, Schwamborn, Jens C., Krüger, Rejko
Published in Stem cell research (01.09.2023)
Published in Stem cell research (01.09.2023)
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Journal Article
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1
Chemla, Axel, Arena, Giuseppe, Saraiva, Claudia, Berenguer-Escuder, Clara, Grossmann, Dajana, Grünewald, Anne, Klein, Christine, Seibler, Philip, Schwamborn, Jens C., Krüger, Rejko
Published in Stem cell research (01.06.2023)
Published in Stem cell research (01.06.2023)
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Journal Article
Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons
Zimyanin, Vitaly L, Pielka, Anna-Maria, Glaß, Hannes, Japtok, Julia, Großmann, Dajana, Martin, Melanie, Deussen, Andreas, Szewczyk, Barbara, Deppmann, Chris, Zunder, Eli, Andersen, Peter M, Boeckers, Tobias M, Sterneckert, Jared, Redemann, Stefanie, Storch, Alexander, Hermann, Andreas
Published in Cells (Basel, Switzerland) (09.05.2023)
Published in Cells (Basel, Switzerland) (09.05.2023)
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Journal Article
Mitochondria interaction networks show altered topological patterns in Parkinson’s disease
Zanin, Massimiliano, Santos, Bruno F. R., Antony, Paul M. A., Berenguer-Escuder, Clara, Larsen, Simone B., Hanss, Zoé, Barbuti, Peter A., Baumuratov, Aidos S., Grossmann, Dajana, Capelle, Christophe M., Weber, Joseph, Balling, Rudi, Ollert, Markus, Krüger, Rejko, Diederich, Nico J., He, Feng Q.
Published in NPJ systems biology and applications (10.11.2020)
Published in NPJ systems biology and applications (10.11.2020)
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Journal Article
Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease
Berenguer-Escuder, Clara, Grossmann, Dajana, Antony, Paul, Arena, Giuseppe, Wasner, Kobi, Massart, François, Jarazo, Javier, Walter, Jonas, Schwamborn, Jens C, Grünewald, Anne, Krüger, Rejko
Published in Human molecular genetics (28.05.2020)
Published in Human molecular genetics (28.05.2020)
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Journal Article
Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons
Grossmann, Dajana, Malburg, Nina, Glaß, Hannes, Weeren, Veronika, Sondermann, Verena, Pfeiffer, Julia F, Petters, Janine, Lukas, Jan, Seibler, Philip, Klein, Christine, Grünewald, Anne, Hermann, Andreas
Published in Movement disorders (01.10.2023)
Published in Movement disorders (01.10.2023)
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Journal Article
Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease
Grossmann, Dajana, Berenguer-Escuder, Clara, Bellet, Marie Estelle, Scheibner, David, Bohler, Jill, Massart, Francois, Rapaport, Doron, Skupin, Alexander, Fouquier d'Hérouël, Aymeric, Sharma, Manu, Ghelfi, Jenny, Raković, Aleksandar, Lichtner, Peter, Antony, Paul, Glaab, Enrico, May, Patrick, Dimmer, Kai Stefan, Fitzgerald, Julia Catherine, Grünewald, Anne, Krüger, Rejko
Published in Antioxidants & redox signaling (01.12.2019)
Published in Antioxidants & redox signaling (01.12.2019)
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Polygenic Risk Scores Validated in Patient‐Derived Cells Stratify for Mitochondrial Subtypes of Parkinson's Disease
Arena, Giuseppe, Landoulsi, Zied, Grossmann, Dajana, Payne, Thomas, Vitali, Armelle, Delcambre, Sylvie, Baron, Alexandre, Antony, Paul, Boussaad, Ibrahim, Bobbili, Dheeraj Reddy, Sreelatha, Ashwin Ashok Kumar, Pavelka, Lukas, Diederich, Nico, Klein, Christine, Seibler, Philip, Glaab, Enrico, Foltynie, Thomas, Bandmann, Oliver, Sharma, Manu, Krüger, Rejko, May, Patrick, Grünewald, Anne
Published in Annals of neurology (01.07.2024)
Published in Annals of neurology (01.07.2024)
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Journal Article
Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy
Neumann, Marie Anne-Catherine, Grossmann, Dajana, Schimpf-Linzenbold, Simone, Dayan, Dana, Stingl, Katarina, Ben-Menachem, Reut, Pines, Ophry, Massart, François, Delcambre, Sylvie, Ghelfi, Jenny, Bohler, Jill, Strom, Tim, Kessel, Amit, Azem, Abdussalam, Schöls, Ludger, Grünewald, Anne, Wissinger, Bernd, Krüger, Rejko
Published in Scientific reports (07.10.2020)
Published in Scientific reports (07.10.2020)
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Journal Article
Variants in Miro1 Cause Alterations of ER-Mitochondria Contact Sites in Fibroblasts from Parkinson's Disease Patients
Berenguer-Escuder, Clara, Grossmann, Dajana, Massart, Franҫois, Antony, Paul, Burbulla, Lena F, Glaab, Enrico, Imhoff, Sophie, Trinh, Joanne, Seibler, Philip, Grünewald, Anne, Krüger, Rejko
Published in Journal of clinical medicine (16.12.2019)
Published in Journal of clinical medicine (16.12.2019)
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Journal Article
Glycolic acid and D-lactate-putative products of DJ-1-restore neurodegeneration in FUS - and SOD1-ALS
Pal, Arun, Grossmann, Dajana, Glaß, Hannes, Zimyanin, Vitaly, Günther, René, Catinozzi, Marica, Boeckers, Tobias M, Sterneckert, Jared, Storkebaum, Erik, Petri, Susanne, Wegner, Florian, Grill, Stephan W, Pan-Montojo, Francisco, Hermann, Andreas
Published in Life science alliance (01.08.2024)
Published in Life science alliance (01.08.2024)
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Journal Article
Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in IFUS/I ALS Motoneurons
Zimyanin, Vitaly L, Pielka, Anna-Maria, Glaß, Hannes, Japtok, Julia, Großmann, Dajana, Ma, Deussen, Andreas, Szewczyk, Barbara, Deppmann, Chris, Zunder, Eli, Andersen, Peter M, Boeckers, Tobias M, Sterneckert, Jared, Redemann, Stefanie, Storch, Alexander, Hermann, Andreas
Published in Cells (Basel, Switzerland) (01.05.2023)
Published in Cells (Basel, Switzerland) (01.05.2023)
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Neuroakanthozytose-Syndrome und Co: Neurodegeneration durch gestörten Massentransfer von Lipiden
Peikert, Kevin, Spanger, Adrian, Fischer, Emily, Bartalis, Anna E., Grossmann, Dajana, Danek, Adrian, Hermann, Andreas
Published in DNP – Die Neurologie & Psychiatrie (01.06.2023)
Published in DNP – Die Neurologie & Psychiatrie (01.06.2023)
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Journal Article
Mitochondria-mitochondria interaction networks show altered topological patterns in Parkinson's disease
Zanin, Massimiliano, Santos, Bruno Fr, Paul Ma Antony, Berenguer-Escuder, Clara, Larsen, Simone B, Hanss, Zoe, Barbuti, Peter, Baumuratov, Aidos S, Grossmann, Dajana, Capelle, Christophe, Weber, Joseph, Balling, Rudi, Ollert, Markus, Krueger, Rejko, Diederich, Nico J, He, Feng Q
Published in bioRxiv (10.03.2020)
Published in bioRxiv (10.03.2020)
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