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Published in Journal of medicinal chemistry (11.01.2018)
Published in Journal of medicinal chemistry (11.01.2018)
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Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
Tsou, Pei-Suen, Lu, Chenyang, Gurrea-Rubio, Mikel, Muraoka, Sei, Campbell, Phillip L, Wu, Qi, Model, Ellen N, Lind, Matthew E, Vichaikul, Sirapa, Mattichak, Megan N, Brodie, William D, Hervoso, Jonatan L, Ory, Sarah, Amarista, Camila I, Pervez, Rida, Junginger, Lucas, Ali, Mustafa, Hodish, Gal, O'Mara, Morgan M, Ruth, Jeffrey H, Robida, Aaron M, Alt, Andrew J, Zhang, Chengxin, Urquhart, Andrew G, Lawton, Jeffrey N, Chung, Kevin C, Maerz, Tristan, Saunders, Thomas L, Groppi, Vincent E, Fox, David A, Amin, M Asif
Published in The Journal of clinical investigation (01.06.2022)
Published in The Journal of clinical investigation (01.06.2022)
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Discovery and Structure−Activity Relationship of Quinuclidine Benzamides as Agonists of α7 Nicotinic Acetylcholine Receptors
Bodnar, Alice L, Cortes-Burgos, Luz A, Cook, Karen K, Dinh, Dac M, Groppi, Vincent E, Hajos, Mihaly, Higdon, Nicole R, Hoffmann, William E, Hurst, Raymond S, Myers, Jason K, Rogers, Bruce N, Wall, Theron M, Wolfe, Mark L, Wong, Erik
Published in Journal of medicinal chemistry (24.02.2005)
Published in Journal of medicinal chemistry (24.02.2005)
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The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics?
Olivier, B, Leahy, C, Mullen, T, Paylor, R, Groppi, V E, Sarnyai, Z, Brunner, D
Published in Psychopharmacology (01.07.2001)
Published in Psychopharmacology (01.07.2001)
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Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders
Gurney, Mark E, Nugent, Richard A, Mo, Xuesheng, Sindac, Janice A, Hagen, Timothy J, Fox, David, O’Donnell, James M, Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Groppi, Vincent E, Bailie, Marc, White, Ronald E, Romero, Donna L, Vellekoop, A. Samuel, Walker, Joel R, Surman, Matthew D, Zhu, Lei, Campbell, Robert F
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor: SAR Investigation Around PNU-120596
Acker, Brad A, Badescu, Valentina O, Berkenpas, Mitchell B, Groppi, Vincent E, Hajós, Mihaly, Higdon, Nicole R, Hurst, Raymond S, Jon Jacobsen, E, Margolis, Brandon J, McWhorter, William W, Myers, Jason K, Piotrowski, David W, Rogers, Bruce N, Sarapa, Dusan, Vetman, Tatiana N, Walker, Daniel P, Wall, Theron M, Wilhite, David M, Wishka, Donn G, Xu, Wenjian, Yates, Karen M
Published in Bioorganic & medicinal chemistry letters (01.09.2023)
Published in Bioorganic & medicinal chemistry letters (01.09.2023)
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High-Throughput Screening for Drugs that Modulate Intermediate Filament Proteins
Sun, Jingyuan, Groppi, Vincent E, Gui, Honglian, Chen, Lu, Xie, Qing, Liu, Li, Omary, M Bishr
Published in Methods in enzymology (01.01.2016)
Published in Methods in enzymology (01.01.2016)
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Discovery of N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia: Synthesis and Structure−Activity Relationship
Wishka, Donn G, Walker, Daniel P, Yates, Karen M, Reitz, Steven C, Jia, Shaojuan, Myers, Jason K, Olson, Kirk L, Jacobsen, E. Jon, Wolfe, Mark L, Groppi, Vincent E, Hanchar, Alexander J, Thornburgh, Bruce A, Cortes-Burgos, Luz A, Wong, Erik H. F, Staton, Brian A, Raub, Thomas J, Higdon, Nicole R, Wall, Theron M, Hurst, Raymond S, Walters, Rodney R, Hoffmann, William E, Hajos, Mihaly, Franklin, Stanley, Carey, Galen, Gold, Lisa H, Cook, Karen K, Sands, Steven B, Zhao, Sabrina X, Soglia, John R, Kalgutkar, Amit S, Arneric, Stephen P, Rogers, Bruce N
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals
Zinser, Erich W, Wolf, Mark L, Alexander-Bowman, Susan J, Thomas, Eileen M, Davis, John P, Groppi, Vincent E, Lee, Byung H, Thompson, David P, Geary, Timothy G
Published in Journal of veterinary pharmacology and therapeutics (01.08.2002)
Published in Journal of veterinary pharmacology and therapeutics (01.08.2002)
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Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3- c]pyridine-5-carboxamide as an agonist of the alpha 7 nicotinic acetylcholine receptor: In vitro and in vivo activity
Acker, Brad A, Jacobsen, EJon, Rogers, Bruce N, Wishka, Donn G, Reitz, Steven C, Piotrowski, David W, Myers, Jason K, Wolfe, Mark L, Groppi, Vincent E, Thornburgh, Bruce A, Tinholt, Paula M, Walters, Rodney R, Olson, Barbara A, Fitzgerald, Laura, Staton, Brian A, Raub, Thomas J, Krause, Michael, Li, Kai S, Hoffmann, William E, Hajos, Mihaly, Hurst, Raymond S, Walker, Daniel P
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha 7 nicotinic acetylcholine receptor agonists
Walker, Daniel P, Wishka, Donn G, Piotrowski, David W, Jia, Shaojuan, Reitz, Steven C, Yates, Karen M, Myers, Jason K, Vetman, Tatiana N, Margolis, Brandon J, Jacobsen, EJon, Acker, Brad A, Groppi, Vincent E, Wolfe, Mark L, Thornburgh, Bruce A, Tinholt, Paula M, Cortes-Burgos, Luz A, Walters, Rodney R, Hester, Matthew R, Seest, Eric P, Dolak, Lester A, Han, Fusen, Olson, Barbara A, Fitzgerald, Laura, Staton, Brian A, Raub, Thomas J, Hajos, Mihaly, Hoffmann, William E, Li, Kai S, Higdon, Nicole R, Wall, Theron M, Hurst, Raymond S, Wong, Erik HF, Rogers, Bruce N
Published in Bioorganic & medicinal chemistry (15.12.2006)
Published in Bioorganic & medicinal chemistry (15.12.2006)
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Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists
Walker, Daniel P., Wishka, Donn G., Piotrowski, David W., Jia, Shaojuan, Reitz, Steven C., Yates, Karen M., Myers, Jason K., Vetman, Tatiana N., Margolis, Brandon J., Jacobsen, E. Jon, Acker, Brad A., Groppi, Vincent E., Wolfe, Mark L., Thornburgh, Bruce A., Tinholt, Paula M., Cortes-Burgos, Luz A., Walters, Rodney R., Hester, Matthew R., Seest, Eric P., Dolak, Lester A., Han, Fusen, Olson, Barbara A., Fitzgerald, Laura, Staton, Brian A., Raub, Thomas J., Hajos, Mihaly, Hoffmann, William E., Li, Kai S., Higdon, Nicole R., Wall, Theron M., Hurst, Raymond S., Wong, Erik H.F., Rogers, Bruce N.
Published in Bioorganic & medicinal chemistry (01.12.2006)
Published in Bioorganic & medicinal chemistry (01.12.2006)
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Positive allosteric modulators of the a7 nicotinic acetylcholine receptor: SAR investigation around PNU-120596
Acker, Brad A., Badescu, Valentina O., Berkenpas, Mitchell B., Groppi, Vincent E., Hajos, Mihaly, Higdon, Nicole R., Hurst, Raymond S., Jacobsen, E. Jon, Margolis, Brandon J., Mcwhorter, William W., Myers, Jason K., Piotrowski, David W., Rogers, Bruce N., Sarapa, Dusan, Vetman, Tatiana N., Walker, Daniel P., Wall, Theron M., Wilhite, David M., Wishka, Donn G., Xu, Wenjian, Yates, Karen M.
Published in Bioorganic & medicinal chemistry letters (01.09.2023)
Published in Bioorganic & medicinal chemistry letters (01.09.2023)
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A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization
Hurst, Raymond S., Hajós, Mihaly, Raggenbass, Mario, Wall, Theron M., Higdon, Nicole R., Lawson, Judy A., Rutherford-Root, Karen L., Berkenpas, Mitchell B., Hoffmann, W. E., Piotrowski, David W., Groppi, Vincent E., Allaman, Geraldine, Ogier, Roch, Bertrand, Sonia, Bertrand, Daniel, Arneric, Stephen P.
Published in The Journal of neuroscience (27.04.2005)
Published in The Journal of neuroscience (27.04.2005)
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Journal Article
A Novel Positive Allosteric Modulator of the alpha 7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization
Hurst, Raymond S, Hajos, Mihaly, Raggenbass, Mario, Wall, Theron M, Higdon, Nicole R, Lawson, Judy A, Rutherford-Root, Karen L, Berkenpas, Mitchell B, Hoffmann, W E, Piotrowski, David W, Groppi, Vincent E, Allaman, Geraldine, Ogier, Roch, Bertrand, Sonia, Bertrand, Daniel, Arneric, Stephen P
Published in The Journal of neuroscience (27.04.2005)
Published in The Journal of neuroscience (27.04.2005)
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Synthesis and biological activity of spirocyclic benzopyran imidazolone potassium channel openers
Gadwood, Robert C, Kamdar, Bharat V, Dubray, Loretta A. Cipkus, Wolfe, Mark L, Smith, Michael P, Watt, William, Mizsak, Stephen A, Groppi, Vincent E
Published in Journal of medicinal chemistry (14.05.1993)
Published in Journal of medicinal chemistry (14.05.1993)
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Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha 7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: Synthesis and structure-activity relationship
Wishka, Donn G., Walker, Daniel P., Yates, Karen M., Reitz, Steven C., Jia, Shaojuan, Myers, Jason K., Olson, Kirk L., Jacobsen, E. Jon, Wolfe, Mark L., Groppi, Vincent E., Hanchar, Alexander J., Thornburgh, Bruce A., Cortes-Burgos, Luz A., Wong, Erik H. F., Staton, Brian A., Raub, Thomas J., Higdon, Nicole R., Wall, Theron M., Hurst, Raymond S., Walters, Rodney R., Hoffmann, William E., Hajos, Mihaly, Franklin, Stanley, Carey, Galen, Gold, Lisa H., Cook, Karen K., Sands, Steven B., Zhao, Sabrina X., Soglia, John R., Kalgutkar, Amit S., Arneric, Stephen P., Rogers, Bruce N.
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Journal Article
Discovery of N-[(3 R,5 R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3- c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity
Acker, Brad A., Jacobsen, E. Jon, Rogers, Bruce N., Wishka, Donn G., Reitz, Steven C., Piotrowski, David W., Myers, Jason K., Wolfe, Mark L., Groppi, Vincent E., Thornburgh, Bruce A., Tinholt, Paula M., Walters, Rodney R., Olson, Barbara A., Fitzgerald, Laura, Staton, Brian A., Raub, Thomas J., Krause, Michael, Li, Kai S., Hoffmann, William E., Hajos, Mihaly, Hurst, Raymond S., Walker, Daniel P.
Published in Bioorganic & medicinal chemistry letters (15.06.2008)
Published in Bioorganic & medicinal chemistry letters (15.06.2008)
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Localization of TIMP in cycling mouse hair
KAWABE, T. T, REA, T. J, FLENNIKEN, A. M, WILLIAMS, B. R. G, GROPPI, V. E, BUHL, A. E
Published in Development (Cambridge) (01.04.1991)
Published in Development (Cambridge) (01.04.1991)
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