Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
Zenz, Thorsten, Häbe, Sonja, Denzel, Tina, Mohr, Julia, Winkler, Dirk, Bühler, Andreas, Sarno, Antonio, Groner, Silja, Mertens, Daniel, Busch, Raymonde, Hallek, Michael, Döhner, Hartmut, Stilgenbauer, Stephan
Published in Blood (24.09.2009)
Published in Blood (24.09.2009)
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Journal Article
Subcutaneous Alemtuzumab in Fludarabine-Refractory Chronic Lymphocytic Leukemia: Clinical Results and Prognostic Marker Analyses From the CLL2H Study of the German Chronic Lymphocytic Leukemia Study Group
Stilgenbauer, Stephan, Zenz, Thorsten, Winkler, Dirk, Bühler, Andreas, Schlenk, Richard F., Groner, Silja, Busch, Raymonde, Hensel, Manfred, Dührsen, Ulrich, Finke, Jürgen, Dreger, Peter, Jäger, Ulrich, Lengfelder, Eva, Hohloch, Karin, Söling, Ulrike, Schlag, Rudolf, Kneba, Michael, Hallek, Michael, Döhner, Hartmut
Published in Journal of clinical oncology (20.08.2009)
Published in Journal of clinical oncology (20.08.2009)
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Journal Article
Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B
Schlenk, Richard F, Dohner, Konstanze, Kneba, Michael, Gotze, Katharina, Hartmann, Frank, del Valle, Francesco, Kirchen, Heinz, Koller, Elisabeth, Fischer, Jorg T, Bullinger, Lars, Habdank, Marianne, Spath, Daniela, Groner, Silja, Krebs, Bernhard, Kayser, Sabine, Corbacioglu, Andrea, Anhalt, Andreas, Benner, Axel, Frohling, Stefan, Dohner, Hartmut, German-Austrian AML Study Group (AMLSG)
Published in Haematologica (Roma) (01.01.2009)
Published in Haematologica (Roma) (01.01.2009)
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Journal Article
Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome
Kayser, Sabine, Schlenk, Richard F., Londono, Martina Correa, Breitenbuecher, Frank, Wittke, Kerstin, Du, Juan, Groner, Silja, Späth, Daniela, Krauter, Jürgen, Ganser, Arnold, Döhner, Hartmut, Fischer, Thomas, Döhner, Konstanze
Published in Blood (17.09.2009)
Published in Blood (17.09.2009)
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Secondary AML After a History of Myelodysplastic Syndrome Is An Independent Adverse Prognostic Factor for Achievement of Complete Remission, Relapse-Free and Overall Survival. An Analysis of 2,819 Adult Patients with Newly Diagnosed AML Enrolled On Seven AMLSG Treatment Trials
Kayser, Sabine, Doehner, Konstanze, Krauter, Juergen, Horst, Heinz A., von Lilienfeld-Toal, Marie, Germing, Ulrich, Goetze, Katharina, Pfreundschuh, Michael, Fiedler, Walter, Spaeth, Daniela, Groner, Silja, Schlegelberger, Brigitte, Goehring, Gudrun, Ganser, Arnold, Doehner, Hartmut, Schlenk, Richard F.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Treatment-Related AML Is An Independent Adverse Prognostic Factor for Relapse-Free and Overall Survival. An Analysis of 2,868 Adult Patients with Newly Diagnosed AML Enrolled On Seven AMLSG Treatment Trials
Kayser, Sabine, Doehner, Konstanze, Krauter, Juergen, Horst, Heinz A., Lilienfeld-Toal, Marie von, Germing, Ulrich, Goetze, Katharina, Pfreundschuh, Michael, Fiedler, Walter, Spaeth, Daniela, Groner, Silja, Schlegelberger, Brigitte, Goehring, Gudrun, Ganser, Arnold, Doehner, Hartmut, Schlenk, Richard F.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Prognostic Implication of Insertion of FLT3 Internal Tandem Duplication in the BETA-1-Sheet of the Tyrosine Kinase Domain-1
Kayser, Sabine, Schlenk, Richard F., Breitenbücher, Frank, Porebski, Martina, Wittke, Kerstin, Du, Juan, Groner, Silja, Spaeth, Daniela, Krauter, Jürgen, Ganser, Arnold, Döhner, Hartmut, Fischer, Thomas, Döhner, Konstanze
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Impact of Pegfilgrastim and Dosing Schedule of Cytarabine on Hematological Reconstitution Times, Incidences of Severe Infection and Duration of Hospitalization after Consolidation Therapy with High-Dose Cytarabine in Acute Myeloid Leukaemia - Interim Results from AMLSG 07-04 Trial
Schlenk, Richard F., Döhner, Konstanze, Groner, Silja, Hartmann, Peer C., Krauter, Jürgen, Ganser, Arnold, Döhner, Hartmut
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Clinical Impact of WT1 Mutations in the Context of Other Molecular Markers in Cytogenetically Normal Acute Myeloid Leukemia (AML): A Study of the German-Austrian AML Study Group (AMLSG)
Gaidzik, Verena I., Habdank, Marianne, Moschny, Simone, Groner, Silja, Spath, Daniela, Krauter, Jurgen, Schlegelberger, Brigitte, Ganser, Arnold, Dohner, Hartmut, Schlenk, Richard F., Dohner, Konstanze
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Role of Etoposide in Combination with All-Trans Retinoic Acid in the Treatment of Elderly Patients with Acute Myeloid Leukemia and NPM1 Mutation
Hütter, Marie-Luise, Döhner, Konstanze, Schmidt-Wolf, Ingo G.H., Valle, Francisco Del, Heydrich, Björn, Heit, Wolfgang, Fiedler, Walter, Pfreundschuh, Michael, Russ, Gudrun, Bentz, Martin, Raghavachar, Aruna, Haase, Detlef, Brugger, Wolfram, Götze, Katharina, Groner, Silja, Döhner, Hartmut, Schlenk, Richard
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Subcutaneous Alemtuzumab (Campath) in Fludarabine-Refractory CLL: Final Results of the CLL2H Trial of the GCLLSG and Comprehensive Analysis of Prognostic Markers
Stilgenbauer, Stephan, Zenz, Thorsten, Winkler, Dirk, Bühler, Andreas, Groner, Silja, Busch, Raymonde, Hensel, Manfred, Dührsen, Ulrich, Finke, Juergen, Dreger, Peter, Jäger, Ulrich, Lengfelder, Eva, Truemper, Lorenz H., Söling, Ulrike, Schlag, Rudolf, Hallek, Michael, Döhner, Hartmut
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
The Impact of Therapy-Related and Secondary AML in Relation to Karyotype and Molecular Markers: A Study of the AMLSG
Kayser, Sabine, Döhner, Konstanze, Krauter, Jürgen, Späth, Daniela, Groner, Silja, Schlegelberger, Brigitte, Göhring, Gudrun, Ganser, Arnold, Döhner, Hartmut, Schlenk, Richard F.
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Subcutaneous Alemtuzumab (MabCampath) in Fludarabine-Refractory CLL (CLL2H Trial of the GCLLSG)
Stilgenbauer, Stephan, Winkler, Dirk, Bühler, Andreas, Zenz, Thorsten, Groner, Silja, Busch, Raymonde, Hensel, Manfred, Dührsen, Ulrich, Finke, Jürgen, Dreger, Peter, Jäger, Ulrich, Lengfelder, Eva, Trümper, Lorenz, Söling, Ulrike, Schlag, Rudolf, Hallek, Michael, Döhner, Hartmut
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
The Genotype NPM1mut/FLT3-ITDneg Is a Highly Significant Predictive Factor for Response to Therapy with All-Trans Retinoic Acid in Acute Myeloid Leukemia - Results from AMLSG Trial AML HD98B
Schlenk, Richard F., Döhner, Konstanze, Kneba, Michael, Valle, Francesco del, Hartmann, Frank, Kirchen, Heinz, Koller, Elisabeth, Götze, Katharina, Fischer, Jörg Th, Habdank, Marianne, Späth, Daniela, Groner, Silja, Corbacioglu, Andrea, Benner, Axel, Fröhling, Stefan, Döhner, Hartmut
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Valproic Acid as Adjunct to Induction Therapy in Patients with Acute Myeloid Leukemia: First Results of Two Randomized Studies of the AMLSG
Schlenk, Richard F., Bommer, Martin, Schmid, Mathias, Fröhling, Stefan, Lehmann, Katrin, Groner, Silja, Hann, Rainer, Krauter, Jürgen, Döhner, Konstanze, Ganser, Arnold, Göttlicher, Martin, Döhner, Hartmut
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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