Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model
Herrera, Victoria L. M., Gromisch, Christopher M., Decano, Julius L., Pasion, Khristine Amber, Tan, Glaiza L. A., Hua, Ning, Takahashi, Courtney E., Greer, David M., Ruiz-Opazo, Nelson
Published in Scientific reports (15.02.2023)
Published in Scientific reports (15.02.2023)
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A targetable ‘rogue’ neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS
Herrera, Victoria L. M., Walkey, Allan J., Nguyen, Mai Q., Gromisch, Christopher M., Mosaddhegi, Julie Z., Gromisch, Matthew S., Jundi, Bakr, Lukassen, Soeren, Carstensen, Saskia, Denis, Ridiane, Belkina, Anna C., Baron, Rebecca M., Pinilla-Vera, Mayra, Mueller, Meike, Kimberly, W. Taylor, Goldstein, Joshua N., Lehmann, Irina, Shih, Angela R., Eils, Roland, Levy, Bruce D., Ruiz-Opazo, Nelson
Published in Scientific reports (04.04.2022)
Published in Scientific reports (04.04.2022)
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Journal Article
Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis ratnu/nu model
Gromisch, Christopher M, Tan, Glaiza L. A, Pasion, Khristine Amber, Moran, Ann-Marie, Gromisch, Matthew S, Grinstaff, Mark W, Carr, Francis J, Herrera, Victoria L. M, Ruiz-Opazo, Nelson
Published in BMC cancer (14.04.2021)
Published in BMC cancer (14.04.2021)
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Journal Article
Humanized anti-DEspR monoclonal antibody to improve overall survival in xenograft pancreatic peritoneal carcinomatosis nude rat model
Gromisch, Christopher, Gromisch, Matthew Stannard, Grinstaff, Mark, Herrera, Victoria L.M., Ruiz-Opazo, Nelson
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Increased Neutrophil-Subset Associated With Severity/Mortality In ARDS And COVID19-ARDS Expresses The Dual Endothelin-1/VEGFsignal-Peptide Receptor (DEspR): An Actionable Therapeutic Target
Herrera, Victoria L M, Walkey, Allan J, Nguyen, Mai Q, Gromisch, Christopher M, Mosaddhegi, Julie Z, Gromisch, Matthew S, Jundi, Bakr, Lukassen, Soeren, Carstensen, Saskia, Denis, Ridiane, Belkina, Anna C, Baron, Rebecca M, Pinilla-Vera, Mayra, Muller, Meike, Kimberly, W Taylor, Goldstein, Joshua N, Lehmann, Irina, Shih, Angela R, Ells, Roland, Levy, Bruce D, Rulz-Opazo, Nelson
Published in Research square (13.09.2021)
Published in Research square (13.09.2021)
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MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer
Wong, Chen Khuan, Gromisch, Christopher, Ozturk, Sait, Papageorgis, Panagiotis, Abdolmaleky, Hamid Mostafavi, Reinhard, Björn M., Thiagalingam, Arunthathi, Thiagalingam, Sam
Published in Cancer biology & therapy (03.08.2019)
Published in Cancer biology & therapy (03.08.2019)
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Journal Article
Humanized anti-DEspR IgG4 S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis rat nu/nu model
Gromisch, Christopher M, Tan, Glaiza L A, Pasion, Khristine Amber, Moran, Ann-Marie, Gromisch, Matthew S, Grinstaff, Mark W, Carr, Francis J, Herrera, Victoria L M, Ruiz-Opazo, Nelson
Published in BMC cancer (14.04.2021)
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Published in BMC cancer (14.04.2021)
Journal Article
Establishment of esophagogastric xenografts: A model for characterizing disease heterogeneity
Janjigian, Yelena Yuriy, Gromisch, Christopher M., Carbonetti, Gregory, Tang, Laura H., Kelsen, David Paul, Coit, Daniel G., Vakiani, Efsevia, de Stanchina, Elisa, Strong, Vivian E.
Published in Journal of clinical oncology (20.10.2012)
Published in Journal of clinical oncology (20.10.2012)
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A phase II study of afatinib in patients (pts) with metastatic human epidermal growth factor receptor (HER2)-positive trastuzumab-refractory esophagogastric (EG) cancer
Janjigian, Yelena Yuriy, Capanu, Marinela, Gromisch, Christopher M., Kelsen, David Paul, Ku, Geoffrey Y., Brown, Karen T., Schattner, Mark, Ilson, David H., Solit, David B., Berger, Michael F., Vakiani, Efsevia
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
NOVEL POLYPEPTIDES AND USES THEREOF
BERRY, Samantha, GROMISCH, Christopher, HAMOUD, Aladin, GRINSTAFF, Mark
Year of Publication 27.04.2023
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Year of Publication 27.04.2023
Patent
NOVEL POLYPEPTIDES AND USES THEREOF
BERRY, Samantha, GROMISCH, Christopher, RINGACI, Alina, HAMOUD, Aladin, GRINSTAFF, Mark
Year of Publication 20.04.2023
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Year of Publication 20.04.2023
Patent
NOVEL POLYPEPTIDES AND USES THEREOF
BERRY, Samantha, GROMISCH, Christopher, RINGACI, Alina, HAMOUD, Aladin, GRINSTAFF, Mark
Year of Publication 02.02.2023
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Year of Publication 02.02.2023
Patent
Polypeptide compositions and methods for site-specific targeting of therapeutic agents
Gromisch, Christopher, Herrera, Victoria, Grinstaff, Mark W, Ruiz-Opazo, Nelson
Year of Publication 23.03.2021
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Year of Publication 23.03.2021
Patent
Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis rat nu/nu model
Christopher M. Gromisch, Glaiza L. A. Tan, Khristine Amber Pasion, Ann-Marie Moran, Matthew S. Gromisch, Mark W. Grinstaff, Francis J. Carr, Victoria L. M. Herrera, Nelson Ruiz-Opazo
Published in BMC cancer (01.04.2021)
Published in BMC cancer (01.04.2021)
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Journal Article
POLYPEPTIDE COMPOSITIONS AND METHODS FOR SITE-SPECIFIC TARGETING OF THERAPEUTIC AGENTS
GRINSTAFF, Mark W, GROMISCH, Christopher, HERRERA, Victoria, RUIZ-OPAZO, Nelson
Year of Publication 19.12.2019
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Year of Publication 19.12.2019
Patent
POLYPEPTIDE COMPOSITIONS AND METHODS FOR SITE-SPECIFIC TARGETING OF THERAPEUTIC AGENTS
GRINSTAFF, Mark W, GROMISCH, Christopher, HERRERA, Victoria, RUIZ-OPAZO, Nelson
Year of Publication 19.12.2019
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Year of Publication 19.12.2019
Patent