Iron-Catalyzed, Fluoroamide-Directed C–H Fluorination
Groendyke, Brian J, AbuSalim, Deyaa I, Cook, Silas P
Published in Journal of the American Chemical Society (05.10.2016)
Published in Journal of the American Chemical Society (05.10.2016)
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Journal Article
Fenton-Inspired C–H Functionalization: Peroxide-Directed C–H Thioetherification
Groendyke, Brian J, Modak, Atanu, Cook, Silas P
Published in Journal of organic chemistry (18.10.2019)
Published in Journal of organic chemistry (18.10.2019)
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Tubulin Resists Degradation by Cereblon-Recruiting PROTACs
Gasic, Ivana, Groendyke, Brian J, Nowak, Radosław P, Yuan, J Christine, Kalabathula, Joann, Fischer, Eric S, Gray, Nathanael S, Mitchison, Timothy J
Published in Cells (Basel, Switzerland) (27.04.2020)
Published in Cells (Basel, Switzerland) (27.04.2020)
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Development and Utility of a PAK1-Selective Degrader
Chow, Hoi-Yee, Karchugina, Sofiia, Groendyke, Brian J., Toenjes, Sean, Hatcher, John, Donovan, Katherine A., Fischer, Eric S., Abalakov, Gleb, Faezov, Bulat, Dunbrack, Roland, Gray, Nathanael S., Chernoff, Jonathan
Published in Journal of medicinal chemistry (08.12.2022)
Published in Journal of medicinal chemistry (08.12.2022)
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Journal Article
Template-assisted covalent modification underlies activity of covalent molecular glues
Li, Yen-Der, Ma, Michelle W., Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Puvar, Kedar, Rutter, Justine C., Lumpkin, Ryan J., Sandoval, Brittany, Jin, Cyrus Y., Schmoker, Anna M., Ficarro, Scott B., Cheong, Hakyung, Metivier, Rebecca J., Wang, Michelle Y., Xu, Shawn, Byun, Woong Sub, Groendyke, Brian J., You, Inchul, Sigua, Logan H., Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M., Park, Paul M. C., Yoon, Hojong, Majewski, Felix C., Sperling, Haniya T., Marto, Jarrod A., Qi, Jun, Nowak, Radosław P., Donovan, Katherine A., Słabicki, Mikołaj, Gray, Nathanael S., Fischer, Eric S., Ebert, Benjamin L.
Published in Nature chemical biology (29.07.2024)
Published in Nature chemical biology (29.07.2024)
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Journal Article
Benzopyrimidodiazepinone inhibitors of TNK2
Groendyke, Brian J., Powell, Chelsea E., Feru, Frederic, Gero, Thomas W., Li, Zhengnian, Szabo, Hilary, Pang, Kevin, Feutrill, John, Chen, Bailing, Li, Bin, Gray, Nathanael S., Scott, David A.
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
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Journal Article
Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing
Li, Zhengnian, Powell, Chelsea E., Groendyke, Brian J., Gero, Thomas W., Feru, Frederic, Feutrill, John, Chen, Bailing, Li, Bin, Szabo, Hilary, Gray, Nathanael S., Scott, David A.
Published in Bioorganic & medicinal chemistry letters (01.10.2020)
Published in Bioorganic & medicinal chemistry letters (01.10.2020)
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Journal Article
Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor
Groendyke, Brian J., Nabet, Behnam, Mohardt, Mikaela L., Zhang, Haisheng, Peng, Ke, Koide, Eriko, Coffey, Calvin R., Che, Jianwei, Scott, David A., Bass, Adam J., Gray, Nathanael S.
Published in ACS medicinal chemistry letters (14.01.2021)
Published in ACS medicinal chemistry letters (14.01.2021)
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Journal Article
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans -labelling Covalent Glues
Hassan, Muhammad Murtaza, Li, Yen-Der, Ma, Michelle W, Teng, Mingxing, Byun, Woong Sub, Puvar, Kedar, Lumpkin, Ryan, Sandoval, Brittany, Rutter, Justine C, Jin, Cyrus Y, Wang, Michelle Y, Xu, Shawn, Schmoker, Anna M, Cheong, Hakyung, Groendyke, Brian J, Qi, Jun, Fischer, Eric S, Ebert, Benjamin L, Gray, Nathanael S
Published in bioRxiv : the preprint server for biology (10.10.2023)
Published in bioRxiv : the preprint server for biology (10.10.2023)
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Journal Article
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
Yen-Der, Li, Ma, Michelle W, Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Kedar Puvar, Lumpkin, Ryan, Sandoval, Brittany, Jin, Cyrus Y, Ficarro, Scott B, Wang, Michelle Y, Xu, Shawn, Groendyke, Brian J, Sigua, Logan H, Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M, Park, Paul M C, Yoon, Hojong, Majewski, Felix C, Marto, Jarrod A, Qi, Jun, Nowak, Radoslaw P, Donovan, Katherine A, Slabicki, Mikolaj, Gray, Nathanael S, Fischer, Eric S, Ebert, Benjamin L
Published in bioRxiv (15.02.2023)
Published in bioRxiv (15.02.2023)
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Journal Article
Abstract 3424: Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders
Li, Yen-Der, Ma, Michelle W., Hassan, Muhammad Murtaza, Puvar, Kedar, Teng, Mingxing, Sandoval, Brittany, Lumpkin, Ryan, Ficarro, Scott B., Wang, Michelle Y., Xu, Shawn, Groendyke, Brian J., Sigua, Logan H., Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M., Park, Paul M., Yoon, Hojong, Nowak, Radosław P., Marto, Jarrod A., Qi, Jun, Donovan, Katherine A., Słabicki, Mikołaj, Gray, Nathanael S., Fischer, Eric S., Ebert, Benjamin L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
Li, Yen-Der, Ma, Michelle W, Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Puvar, Kedar, Lumpkin, Ryan, Sandoval, Brittany, Jin, Cyrus Y, Ficarro, Scott B, Wang, Michelle Y, Xu, Shawn, Groendyke, Brian J, Sigua, Logan H, Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M, Park, Paul M C, Yoon, Hojong, Majewski, Felix C, Marto, Jarrod A, Qi, Jun, Nowak, Radosław P, Donovan, Katherine A, Słabicki, Mikołaj, Gray, Nathanael S, Fischer, Eric S, Ebert, Benjamin L
Published in bioRxiv : the preprint server for biology (15.02.2023)
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Published in bioRxiv : the preprint server for biology (15.02.2023)
Journal Article
Development and utility of a PAK1-selective degrader
Hoi-Yee Chow, Karchugina, Sofia, Groendyke, Brian J, Toenjes, Sean, Hatcher, John, Donovan, Katherine A, Fischer, Eric S, Abalakov, Gleb, Bulat Faezov, Dunbrack, Roland L, Gray, Nathanael S, Chernoff, Jonathan
Published in bioRxiv (13.05.2022)
Published in bioRxiv (13.05.2022)
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