Structure-based inhibitors of amyloid beta core suggest a common interface with tau
Griner, Sarah L, Seidler, Paul, Bowler, Jeannette, Murray, Kevin A, Yang, Tianxiao Peter, Sahay, Shruti, Sawaya, Michael R, Cascio, Duilio, Rodriguez, Jose A, Philipp, Stephan, Sosna, Justyna, Glabe, Charles G, Gonen, Tamir, Eisenberg, David S
Published in eLife (15.10.2019)
Published in eLife (15.10.2019)
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Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils
Tayeb-Fligelman, Einav, Bowler, Jeannette T., Tai, Christen E., Sawaya, Michael R., Jiang, Yi Xiao, Garcia, Gustavo, Griner, Sarah L., Cheng, Xinyi, Salwinski, Lukasz, Lutter, Liisa, Seidler, Paul M., Lu, Jiahui, Rosenberg, Gregory M., Hou, Ke, Abskharon, Romany, Pan, Hope, Zee, Chih-Te, Boyer, David R., Li, Yan, Anderson, Daniel H., Murray, Kevin A., Falcon, Genesis, Cascio, Duilio, Saelices, Lorena, Damoiseaux, Robert, Arumugaswami, Vaithilingaraja, Guo, Feng, Eisenberg, David S.
Published in Nature communications (25.04.2023)
Published in Nature communications (25.04.2023)
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The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical
Galilee, Meytal, Britan-Rosich, Elena, Griner, Sarah L., Uysal, Serdar, Baumgärtel, Viola, Lamb, Don C., Kossiakoff, Anthony A., Kotler, Moshe, Stroud, Robert M., Marx, Ailie, Alian, Akram
Published in Structure (London) (01.11.2016)
Published in Structure (London) (01.11.2016)
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Journal Article
Fabs Enable Single Particle cryoEM Studies of Small Proteins
Wu, Shenping, Avila-Sakar, Agustin, Kim, JungMin, Booth, David S., Greenberg, Charles H., Rossi, Andrea, Liao, Maofu, Li, Xueming, Alian, Akram, Griner, Sarah L., Juge, Narinobu, Yu, Yadong, Mergel, Claudia M., Chaparro-Riggers, Javier, Strop, Pavel, Tampé, Robert, Edwards, Robert H., Stroud, Robert M., Craik, Charles S., Cheng, Yifan
Published in Structure (London) (04.04.2012)
Published in Structure (London) (04.04.2012)
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Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs
Alian, Akram, Griner, Sarah L, Chiang, Vicki, Tsiang, Manuel, Jones, Gregg, Birkus, Gabriel, Geleziunas, Romas, Leavitt, Andrew D, Stroud, Robert M
Published in Proceedings of the National Academy of Sciences - PNAS (19.05.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (19.05.2009)
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Journal Article
De novo designed protein inhibitors of amyloid aggregation and seeding
Murray, Kevin A, Hu, Carolyn J, Griner, Sarah L, Pan, Hope, Bowler, Jeannette T, Abskharon, Romany, Rosenberg, Gregory M, Cheng, Xinyi, Seidler, Paul M, Eisenberg, David S
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2022)
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Journal Article
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors
Krotee, Pascal, Griner, Sarah L., Sawaya, Michael R., Cascio, Duilio, Rodriguez, Jose A., Shi, Dan, Philipp, Stephan, Murray, Kevin, Saelices, Lorena, Lee, Ji, Seidler, Paul, Glabe, Charles G., Jiang, Lin, Gonen, Tamir, Eisenberg, David S.
Published in The Journal of biological chemistry (23.02.2018)
Published in The Journal of biological chemistry (23.02.2018)
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Journal Article
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m⁵U methyltransferases
Alian, Akram, Lee, Tom T, Griner, Sarah L, Stroud, Robert M, Finer-Moore, Janet
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
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Roles of the A and C Sites in the Manganese-Specific Activation of MntR
McGuire, Amanda M, Cuthbert, Bonnie J, Ma, Zhen, Grauer-Gray, Kristen D, Brunjes Brophy, Megan, Spear, Kayce A, Soonsanga, Sumarin, Kliegman, Joseph I, Griner, Sarah L, Helmann, John D, Glasfeld, Arthur
Published in Biochemistry (Easton) (29.01.2013)
Published in Biochemistry (Easton) (29.01.2013)
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Journal Article
Crystal Structure of an RluF–RNA Complex: A Base-Pair Rearrangement Is the Key to Selectivity of RluF for U2604 of the Ribosome
Alian, Akram, DeGiovanni, Andrew, Griner, Sarah L., Finer-Moore, Janet S., Stroud, Robert M.
Published in Journal of molecular biology (15.05.2009)
Published in Journal of molecular biology (15.05.2009)
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Journal Article
Structure of a TrmA–RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m 5 U methyltransferases
Alian, Akram, Lee, Tom T., Griner, Sarah L., Stroud, Robert M., Finer-Moore, Janet
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
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Journal Article
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m^sup 5^U methyltransferases
Alian, Akram, Lee, Tom T, Griner, Sarah L, Stroud, Robert M, Finer-Moore, Janet
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
Journal Article
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m super(5)U methyltransferases
Alian, Akram, Lee, Tom T, Griner, Sarah L, Stroud, Robert M, Finer-Moore, Janet
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2008)
Journal Article
Structure of a TrmA–RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases
Akram Alian, Tom T. Lee, Sarah L. Griner, Robert M. Stroud, Janet Finer-Moore
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
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