ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
Shi, Yang, Yamada, Kaoru, Liddelow, Shane Antony, Smith, Scott T., Zhao, Lingzhi, Luo, Wenjie, Tsai, Richard M., Spina, Salvatore, Grinberg, Lea T., Rojas, Julio C., Gallardo, Gilbert, Wang, Kairuo, Roh, Joseph, Robinson, Grace, Finn, Mary Beth, Jiang, Hong, Sullivan, Patrick M., Baufeld, Caroline, Wood, Michael W., Sutphen, Courtney, McCue, Lena, Xiong, Chengjie, Del-Aguila, Jorge L., Morris, John C., Cruchaga, Carlos, Fagan, Anne M., Miller, Bruce L., Boxer, Adam L., Seeley, William W., Butovsky, Oleg, Barres, Ben A., Paul, Steven M., Holtzman, David M.
Published in Nature (London) (28.09.2017)
Published in Nature (London) (28.09.2017)
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Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
Sanders, David W., Kaufman, Sarah K., DeVos, Sarah L., Sharma, Apurwa M., Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J., Foley, Alex C., Thorpe, Julian R., Serpell, Louise C., Miller, Timothy M., Grinberg, Lea T., Seeley, William W., Diamond, Marc I.
Published in Neuron (Cambridge, Mass.) (18.06.2014)
Published in Neuron (Cambridge, Mass.) (18.06.2014)
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Journal Article
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease
Leng, Kun, Li, Emmy, Eser, Rana, Piergies, Antonia, Sit, Rene, Tan, Michelle, Neff, Norma, Li, Song Hua, Rodriguez, Roberta Diehl, Suemoto, Claudia Kimie, Leite, Renata Elaine Paraizo, Ehrenberg, Alexander J., Pasqualucci, Carlos A., Seeley, William W., Spina, Salvatore, Heinsen, Helmut, Grinberg, Lea T., Kampmann, Martin
Published in Nature neuroscience (01.02.2021)
Published in Nature neuroscience (01.02.2021)
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Journal Article
Tau-driven degeneration of sleep- and wake-regulating neurons in Alzheimer’s disease
Lew, Caroline H., Petersen, Cathrine, Neylan, Thomas C., Grinberg, Lea T.
Published in Sleep medicine reviews (01.12.2021)
Published in Sleep medicine reviews (01.12.2021)
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Journal Article
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Wang, Chao, Fan, Li, Khawaja, Rabia R., Liu, Bangyan, Zhan, Lihong, Kodama, Lay, Chin, Marcus, Li, Yaqiao, Le, David, Zhou, Yungui, Condello, Carlo, Grinberg, Lea T., Seeley, William W., Miller, Bruce L., Mok, Sue-Ann, Gestwicki, Jason E., Cuervo, Ana Maria, Luo, Wenjie, Gan, Li
Published in Nature communications (12.04.2022)
Published in Nature communications (12.04.2022)
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Journal Article
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease
Wesseling, Hendrik, Mair, Waltraud, Kumar, Mukesh, Schlaffner, Christoph N., Tang, Shaojun, Beerepoot, Pieter, Fatou, Benoit, Guise, Amanda J., Cheng, Long, Takeda, Shuko, Muntel, Jan, Rotunno, Melissa S., Dujardin, Simon, Davies, Peter, Kosik, Kenneth S., Miller, Bruce L., Berretta, Sabina, Hedreen, John C., Grinberg, Lea T., Seeley, William W., Hyman, Bradley T., Steen, Hanno, Steen, Judith A.
Published in Cell (10.12.2020)
Published in Cell (10.12.2020)
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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
Prusiner, Stanley B., Woerman, Amanda L., Mordes, Daniel A., Watts, Joel C., Rampersaud, Ryan, Berry, David B., Patel, Smita, Oehler, Abby, Lowe, Jennifer K., Kravitz, Stephanie N., Geschwind, Daniel H., Glidden, David V., Halliday, Glenda M., Middleton, Lefkos T., Gentleman, Steve M., Grinberg, Lea T., Giles, Kurt
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
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Journal Article
Don't die like me: Which proteins are responsible for the selective neuronal vulnerability within the substantia nigra?
Steinbach, Simone, Molina, Mariana, Grinberg, Lea T, Aring, Luisa, Guntermann, Annika, Marcus, Katrin, Heinsen, Helmut, Paraizo Leite, Renata E, May, Caroline
Published in PloS one (31.07.2024)
Published in PloS one (31.07.2024)
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Journal Article
The role of co-neurotransmitters in sleep and wake regulation
Oh, Jun, Petersen, Cathrine, Walsh, Christine M., Bittencourt, Jackson C., Neylan, Thomas C., Grinberg, Lea T.
Published in Molecular psychiatry (01.09.2019)
Published in Molecular psychiatry (01.09.2019)
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Journal Article
Typical and atypical pathology in primary progressive aphasia variants
Spinelli, Edoardo G., Mandelli, Maria Luisa, Miller, Zachary A., Santos‐Santos, Miguel A, Wilson, Stephen M., Agosta, Federica, Grinberg, Lea T., Huang, Eric J., Trojanowski, John Q., Meyer, Marita, Henry, Maya L., Comi, Giancarlo, Rabinovici, Gil, Rosen, Howard J., Filippi, Massimo, Miller, Bruce L., Seeley, William W., Gorno‐Tempini, Maria Luisa
Published in Annals of neurology (01.03.2017)
Published in Annals of neurology (01.03.2017)
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Journal Article
Comorbid neuropathological diagnoses in early versus late-onset Alzheimer's disease
Spina, Salvatore, La Joie, Renaud, Petersen, Cathrine, Nolan, Amber L, Cuevas, Deion, Cosme, Celica, Hepker, Mackenzie, Hwang, Ji-Hye, Miller, Zachary A, Huang, Eric J, Karydas, Anna M, Grant, Harli, Boxer, Adam L, Gorno-Tempini, Maria Luisa, Rosen, Howard J, Kramer, Joel H, Miller, Bruce L, Seeley, William W, Rabinovici, Gil D, Grinberg, Lea T
Published in Brain (London, England : 1878) (09.03.2021)
Published in Brain (London, England : 1878) (09.03.2021)
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Journal Article
18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases
Soleimani-Meigooni, David N, Iaccarino, Leonardo, La Joie, Renaud, Baker, Suzanne, Bourakova, Viktoriya, Boxer, Adam L, Edwards, Lauren, Eser, Rana, Gorno-Tempini, Maria-Luisa, Jagust, William J, Janabi, Mustafa, Kramer, Joel H, Lesman-Segev, Orit H, Mellinger, Taylor, Miller, Bruce L, Pham, Julie, Rosen, Howard J, Spina, Salvatore, Seeley, William W, Strom, Amelia, Grinberg, Lea T, Rabinovici, Gil D
Published in Brain (London, England : 1878) (05.12.2020)
Published in Brain (London, England : 1878) (05.12.2020)
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Journal Article
Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells
Woerman, Amanda L., Aoyagi, Atsushi, Patel, Smita, Kazmi, Sabeen A., Lobach, Iryna, Grinberg, Lea T., McKee, Ann C., Seeley, William W., Olson, Steven H., Prusiner, Stanley B.
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
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Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study
Suemoto, Claudia K, Ferretti-Rebustini, Renata E L, Rodriguez, Roberta D, Leite, Renata E P, Soterio, Luciana, Brucki, Sonia M D, Spera, Raphael R, Cippiciani, Tarcila M, Farfel, Jose M, Chiavegatto Filho, Alexandre, Naslavsky, Michel Satya, Zatz, Mayana, Pasqualucci, Carlos A, Jacob-Filho, Wilson, Nitrini, Ricardo, Grinberg, Lea T
Published in PLoS medicine (28.03.2017)
Published in PLoS medicine (28.03.2017)
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Journal Article
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation
Villeneuve, Sylvia, Rabinovici, Gil D, Cohn-Sheehy, Brendan I, Madison, Cindee, Ayakta, Nagehan, Ghosh, Pia M, La Joie, Renaud, Arthur-Bentil, Samia Kate, Vogel, Jacob W, Marks, Shawn M, Lehmann, Manja, Rosen, Howard J, Reed, Bruce, Olichney, John, Boxer, Adam L, Miller, Bruce L, Borys, Ewa, Jin, Lee-Way, Huang, Eric J, Grinberg, Lea T, DeCarli, Charles, Seeley, William W, Jagust, William
Published in Brain (London, England : 1878) (01.07.2015)
Published in Brain (London, England : 1878) (01.07.2015)
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Journal Article
Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration
Mattsson-Carlgren, Niklas, Grinberg, Lea T, Boxer, Adam, Ossenkoppele, Rik, Jonsson, Magnus, Seeley, William, Ehrenberg, Alexander, Spina, Salvatore, Janelidze, Shorena, Rojas-Martinex, Julio, Rosen, Howard, La Joie, Renaud, Lesman-Segev, Orit, Iaccarino, Leonardo, Kollmorgen, Gwendlyn, Ljubenkov, Peter, Eichenlaub, Udo, Gorno-Tempini, Maria Luisa, Miller, Bruce, Hansson, Oskar, Rabinovici, Gil Dan
Published in Neurology (15.03.2022)
Published in Neurology (15.03.2022)
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