Nrf2 Amplifies Oxidative Stress via Induction of Klf9
Zucker, Shoshanna N., Fink, Emily E., Bagati, Archis, Mannava, Sudha, Bianchi-Smiraglia, Anna, Bogner, Paul N., Wawrzyniak, Joseph A., Foley, Colleen, Leonova, Katerina I., Grimm, Melissa J., Moparthy, Kalyana, Ionov, Yurij, Wang, Jianmin, Liu, Song, Sexton, Sandra, Kandel, Eugene S., Bakin, Andrei V., Zhang, Yuesheng, Kaminski, Naftali, Segal, Brahm H., Nikiforov, Mikhail A.
Published in Molecular cell (20.03.2014)
Published in Molecular cell (20.03.2014)
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Journal Article
Mitochondrial DNA released by trauma induces neutrophil extracellular traps
Itagaki, Kiyoshi, Kaczmarek, Elzbieta, Lee, Yen Ting, Tang, I Tien, Isal, Burak, Adibnia, Yashar, Sandler, Nicola, Grimm, Melissa J, Segal, Brahm H, Otterbein, Leo E, Hauser, Carl J
Published in PloS one (16.03.2015)
Published in PloS one (16.03.2015)
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Journal Article
Regulation of innate immunity by NADPH oxidase
Segal, Brahm H., Grimm, Melissa J., Khan, A. Nazmul H., Han, Wei, Blackwell, Timothy S.
Published in Free radical biology & medicine (01.07.2012)
Published in Free radical biology & medicine (01.07.2012)
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Journal Article
Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections
Pizzolla, Angela, Hultqvist, Malin, Nilson, Bo, Grimm, Melissa J, Eneljung, Tove, Jonsson, Ing-Marie, Verdrengh, Margareta, Kelkka, Tiina, Gjertsson, Inger, Segal, Brahm H, Holmdahl, Rikard
Published in The Journal of immunology (1950) (15.05.2012)
Published in The Journal of immunology (1950) (15.05.2012)
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Journal Article
Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes
Kaloriti, Despoina, Jacobsen, Mette, Yin, Zhikang, Patterson, Miranda, Tillmann, Anna, Smith, Deborah A, Cook, Emily, You, Tao, Grimm, Melissa J, Bohovych, Iryna, Grebogi, Celso, Segal, Brahm H, Gow, Neil A R, Haynes, Ken, Quinn, Janet, Brown, Alistair J P
Published in mBio (15.07.2014)
Published in mBio (15.07.2014)
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Journal Article
Systemic infusion of TLR3-ligand and IFN-α in patients with breast cancer reprograms local tumor microenvironments for selective CTL influx
Gandhi, Shipra, Opyrchal, Mateusz, Grimm, Melissa J, Slomba, Ronald T, Kokolus, Kathleen M, Witkiewicz, Agnieszka, Attwood, Kristopher, Groman, Adrienne, Williams, Lauren, Tarquini, Mary Lynne, Wallace, Paul K, Soh, Kah Teong, Minderman, Hans, Maguire, Orla, O’Connor, Tracey L, Early, Amy P, Levine, Ellis G, Kalinski, Pawel
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice
Grimm, Melissa J, Vethanayagam, R Robert, Almyroudis, Nikolaos G, Dennis, Carly G, Khan, A Nazmul H, D'Auria, Anthony C, Singel, Kelly L, Davidson, Bruce A, Knight, Paul R, Blackwell, Timothy S, Hohl, Tobias M, Mansour, Michael K, Vyas, Jatin M, Röhm, Marc, Urban, Constantin F, Kelkka, Tiina, Holmdahl, Rikard, Segal, Brahm H
Published in The Journal of immunology (1950) (15.04.2013)
Published in The Journal of immunology (1950) (15.04.2013)
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Journal Article
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense
Vethanayagam, R Robert, Almyroudis, Nikolaos G, Grimm, Melissa J, Lewandowski, David C, Pham, Christine T N, Blackwell, Timothy S, Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J, Urban, Constantin F, Segal, Brahm H
Published in PloS one (07.12.2011)
Published in PloS one (07.12.2011)
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Journal Article
Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer
Singel, Kelly L., Grzankowski, Kassondra S., Khan, A. N. M. Nazmul H., Grimm, Melissa J., D’Auria, Anthony C., Morrell, Kayla, Eng, Kevin H., Hylander, Bonnie, Mayor, Paul C., Emmons, Tiffany R., Lénárt, Nikolett, Fekete, Rebeka, Környei, Zsuzsanna, Muthukrishnan, Uma, Gilthorpe, Jonathan D., Urban, Constantin F., Itagaki, Kiyoshi, Hauser, Carl J., Leifer, Cynthia, Moysich, Kirsten B., Odunsi, Kunle, Dénes, Ádám, Segal, Brahm H.
Published in British journal of cancer (2019)
Published in British journal of cancer (2019)
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Journal Article
Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice
Godoy, Heidi E, Khan, A Nazmul H, Vethanayagam, R Robert, Grimm, Melissa J, Singel, Kelly L, Kolomeyevskaya, Nonna, Sexton, Kevin J, Parameswaran, Anupama, Abrams, Scott I, Odunsi, Kunle, Segal, Brahm H
Published in PloS one (26.07.2013)
Published in PloS one (26.07.2013)
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Journal Article
Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer
Khan, Anm Nazmul H, Kolomeyevskaya, Nonna, Singel, Kelly L, Grimm, Melissa J, Moysich, Kirsten B, Daudi, Sayeema, Grzankowski, Kassondra S, Lele, Sashikant, Ylagan, Lourdes, Webster, Gill A, Abrams, Scott I, Odunsi, Kunle, Segal, Brahm H
Published in Oncotarget (10.05.2015)
Published in Oncotarget (10.05.2015)
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Journal Article
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury
Davidson, Bruce A, Vethanayagam, R Robert, Grimm, Melissa J, Mullan, Barbara A, Raghavendran, Krishnan, Blackwell, Timothy S, Freeman, Michael L, Ayyasamy, Vanniarajan, Singh, Keshav K, Sporn, Michael B, Itagaki, Kiyoshi, Hauser, Carl J, Knight, Paul R, Segal, Brahm H
Published in The Journal of immunology (1950) (15.02.2013)
Published in The Journal of immunology (1950) (15.02.2013)
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Journal Article
Heat shock proteins HSP70 and GP96: structural insights
Facciponte, John G, Wang, Xiang-Yang, MacDonald, Ian J, Park, Jun-eui, Arnouk, Hilal, Grimm, Melissa J, Li, Ying, Kim, Hyung, Manjili, Masoud H, Easton, Douglas P, Subjeck, John R
Published in Cancer Immunology, Immunotherapy (01.03.2006)
Published in Cancer Immunology, Immunotherapy (01.03.2006)
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Journal Article
A role for the thermal environment in defining co-stimulation requirements for CD4(+) T cell activation
Zynda, Evan R, Grimm, Melissa J, Yuan, Min, Zhong, Lingwen, Mace, Thomas A, Capitano, Maegan, Ostberg, Julie R, Lee, Kelvin P, Pralle, Arnd, Repasky, Elizabeth A
Published in Cell cycle (Georgetown, Tex.) (01.01.2015)
Published in Cell cycle (Georgetown, Tex.) (01.01.2015)
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Journal Article
Assessing anti-fungal activity of isolated alveolar macrophages by confocal microscopy
Grimm, Melissa J, D'Auria, Anthony C, Segal, Brahm H
Published in Journal of visualized experiments (09.07.2014)
Published in Journal of visualized experiments (09.07.2014)
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Journal Article
Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy
Grimm, Melissa J., D'Auria, Anthony C., Segal, Brahm H.
Published in Journal of visualized experiments (09.07.2014)
Published in Journal of visualized experiments (09.07.2014)
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Journal Article