APP Function and Lipids: A Bidirectional Link
Grimm, Marcus O W, Mett, Janine, Grimm, Heike S, Hartmann, Tobias
Published in Frontiers in molecular neuroscience (10.03.2017)
Published in Frontiers in molecular neuroscience (10.03.2017)
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Journal Article
Methylxanthines and Neurodegenerative Diseases: An Update
Janitschke, Daniel, Lauer, Anna A, Bachmann, Cornel M, Grimm, Heike S, Hartmann, Tobias, Grimm, Marcus O W
Published in Nutrients (28.02.2021)
Published in Nutrients (28.02.2021)
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Journal Article
Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation
Grimm, Marcus O W, Thiel, Andrea, Lauer, Anna A, Winkler, Jakob, Lehmann, Johannes, Regner, Liesa, Nelke, Christopher, Janitschke, Daniel, Benoist, Céline, Streidenberger, Olga, Stötzel, Hannah, Endres, Kristina, Herr, Christian, Beisswenger, Christoph, Grimm, Heike S, Bals, Robert, Lammert, Frank, Hartmann, Tobias
Published in International journal of molecular sciences (19.12.2017)
Published in International journal of molecular sciences (19.12.2017)
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Journal Article
Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells
Janitschke, Daniel, Lauer, Anna A, Bachmann, Cornel M, Seyfried, Martin, Grimm, Heike S, Hartmann, Tobias, Grimm, Marcus O W
Published in International journal of molecular sciences (27.11.2020)
Published in International journal of molecular sciences (27.11.2020)
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Journal Article
From brain to food: Analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin–plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry
Grimm, Marcus O.W., Grösgen, Sven, Riemenschneider, Matthias, Tanila, Heikki, Grimm, Heike S., Hartmann, Tobias
Published in Journal of Chromatography A (21.10.2011)
Published in Journal of Chromatography A (21.10.2011)
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Journal Article
Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin
Lauer, Anna A., Janitschke, Daniel, dos Santos Guilherme, Malena, Nguyen, Vu Thu Thuy, Bachmann, Cornel M., Qiao, Sen, Schrul, Bianca, Boehm, Ulrich, Grimm, Heike S., Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O. W.
Published in Scientific reports (27.07.2021)
Published in Scientific reports (27.07.2021)
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Journal Article
The Influence of Acitretin on Brain Lipidomics in Adolescent Mice-Implications for Pediatric and Adolescent Dermatological Therapy
Lauer, Anna A, Nguyen, Vu Thu Thuy, Janitschke, Daniel, Dos Santos Guilherme, Malena, Bachmann, Cornel M, Grimm, Heike S, Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O W
Published in International journal of molecular sciences (08.12.2022)
Published in International journal of molecular sciences (08.12.2022)
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Journal Article
Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease
Grimm, Marcus O.W, Kuchenbecker, Johanna, Rothhaar, Tatjana L, Grösgen, Sven, Hundsdörfer, Benjamin, Burg, Verena K, Friess, Petra, Müller, Ulrike, Grimm, Heike S, Riemenschneider, Mathias, Hartmann, Tobias
Published in Journal of neurochemistry (01.03.2011)
Published in Journal of neurochemistry (01.03.2011)
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Journal Article
Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer's Disease
Grimm, Marcus O W, Regner, Liesa, Mett, Janine, Stahlmann, Christoph P, Schorr, Pascal, Nelke, Christopher, Streidenberger, Olga, Stoetzel, Hannah, Winkler, Jakob, Zaidan, Shatha R, Thiel, Andrea, Endres, Kristina, Grimm, Heike S, Volmer, Dietrich A, Hartmann, Tobias
Published in International journal of molecular sciences (01.11.2016)
Published in International journal of molecular sciences (01.11.2016)
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Journal Article
The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer’s Disease
Grimm, Heike S., Lehmann, Johannes, Zimmer, Valerie C., Grimm, Marcus O. W., Hartmann, Tobias
Published in BioMed research international (01.01.2013)
Published in BioMed research international (01.01.2013)
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Journal Article
Medium-Chain Length Fatty Acids Enhance Aβ Degradation by Affecting Insulin-Degrading Enzyme
Mett, Janine, Lauer, Anna A, Janitschke, Daniel, Griebsch, Lea V, Theiss, Elena L, Grimm, Heike S, Koivisto, Hennariikka, Tanila, Heikki, Hartmann, Tobias, Grimm, Marcus O W
Published in Cells (Basel, Switzerland) (29.10.2021)
Published in Cells (Basel, Switzerland) (29.10.2021)
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Journal Article
Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism
Grimm, Marcus O W, Zinser, Eva G, Grösgen, Sven, Hundsdörfer, Benjamin, Rothhaar, Tatjana L, Burg, Verena K, Kaestner, Lars, Bayer, Thomas A, Lipp, Peter, Müller, Ulrike, Grimm, Heike S, Hartmann, Tobias
Published in PloS one (28.03.2012)
Published in PloS one (28.03.2012)
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Journal Article
Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer’s Disease
Grimm, Heike S., Hartmann, Tobias, Grimm, Marcus O. W., Rothhaar, Tatjana L., Riemenschneider, Matthias, Mett, Janine, Hundsdörfer, Benjamin, Grösgen, Sven, Haupenthal, Viola J., Burg, Verena K.
Published in TheScientificWorld (01.01.2012)
Published in TheScientificWorld (01.01.2012)
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Journal Article
Effect of Different Phospholipids on α-Secretase Activity in the Non-Amyloidogenic Pathway of Alzheimer's Disease
Grimm, Marcus O W, Haupenthal, Viola J, Rothhaar, Tatjana L, Zimmer, Valerie C, Grösgen, Sven, Hundsdörfer, Benjamin, Lehmann, Johannes, Grimm, Heike S, Hartmann, Tobias
Published in International journal of molecular sciences (13.03.2013)
Published in International journal of molecular sciences (13.03.2013)
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Journal Article
PS Dependent APP Cleavage Regulates Glucosylceramide Synthase and is Affected in Alzheimer's Disease
Grimm, Marcus O.W., Hundsdörfer, Benjamin, Grösgen, Sven, Mett, Janine, Zimmer, Valerie C., Stahlmann, Christoph P., Haupenthal, Viola J., Rothhaar, Tatjana L., Lehmann, Johannes, Pätzold, Andreas, Zinser, Eva G., Tanila, Heikki, Shen, Jie, Müller, Ulrike, Grimm, Heike S., Hartmann, Tobias
Published in Cellular physiology and biochemistry (01.01.2014)
Published in Cellular physiology and biochemistry (01.01.2014)
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Journal Article
Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease
Grösgen, Sven, Grimm, Marcus O. W., Rothhaar, Tatjana L., Burg, Verena K., Hundsdörfer, Benjamin, Haupenthal, Viola J., Friess, Petra, Müller, Ulrike, Fassbender, Klaus, Riemenschneider, Matthias, Grimm, Heike S., Hartmann, Tobias
Published in International journal of alzheimer's disease (2011)
Published in International journal of alzheimer's disease (2011)
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Journal Article
Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms
Grimm, Marcus O.W., Kuchenbecker, Johanna, Grösgen, Sven, Burg, Verena K., Hundsdörfer, Benjamin, Rothhaar, Tatjana L., Friess, Petra, de Wilde, Martijn C., Broersen, Laus M., Penke, Botond, Péter, Mária, Vígh, László, Grimm, Heike S., Hartmann, Tobias
Published in The Journal of biological chemistry (22.04.2011)
Published in The Journal of biological chemistry (22.04.2011)
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Journal Article
Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study
Burg, Verena K, Grimm, Heike S, Rothhaar, Tatjana L, Grösgen, Sven, Hundsdörfer, Benjamin, Haupenthal, Viola J, Zimmer, Valerie C, Mett, Janine, Weingärtner, Oliver, Laufs, Ulrich, Broersen, Laus M, Tanila, Heikki, Vanmierlo, Tim, Lütjohann, Dieter, Hartmann, Tobias, Grimm, Marcus O W
Published in The Journal of neuroscience (09.10.2013)
Published in The Journal of neuroscience (09.10.2013)
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Journal Article
The Intramembrane Cleavage Site of the Amyloid Precursor Protein Depends on the Length of Its Transmembrane Domain
Lichtenthaler, Stefan F., Beher, Dirk, Grimm, Heike S., Wang, Rong, Shearman, Mark S., Masters, Colin L., Beyreuther, Konrad
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
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Journal Article
Eicosapentaenoic acid and docosahexaenoic acid increase the degradation of amyloid-β by affecting insulin-degrading enzyme
Grimm, Marcus O W, Mett, Janine, Stahlmann, Christoph P, Haupenthal, Viola J, Blümel, Tamara, Stötzel, Hannah, Grimm, Heike S, Hartmann, Tobias
Published in Biochemistry and cell biology (01.12.2016)
Published in Biochemistry and cell biology (01.12.2016)
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Journal Article