The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme
Walker, Alexander P, Fan, Haitian, Keown, Jeremy R, Knight, Michael L, Grimes, Jonathan M, Fodor, Ervin
Published in Nucleic acids research (16.12.2021)
Published in Nucleic acids research (16.12.2021)
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Host ANP32A mediates the assembly of the influenza virus replicase
Carrique, Loïc, Fan, Haitian, Walker, Alexander P, Keown, Jeremy R, Sharps, Jane, Staller, Ecco, Barclay, Wendy S, Fodor, Ervin, Grimes, Jonathan M
Published in Nature (London) (26.11.2020)
Published in Nature (London) (26.11.2020)
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Detection of a fourth orbivirus non-structural protein
Belhouchet, Mourad, Mohd Jaafar, Fauziah, Firth, Andrew E, Grimes, Jonathan M, Mertens, Peter P C, Attoui, Houssam
Published in PloS one (12.10.2011)
Published in PloS one (12.10.2011)
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The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome
Wang, Fangzheng, Sheppard, Carol M, Mistry, Bhakti, Staller, Ecco, Barclay, Wendy S, Grimes, Jonathan M, Fodor, Ervin, Fan, Haitian
Published in Nucleic acids research (10.06.2022)
Published in Nucleic acids research (10.06.2022)
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3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway
Kounatidis, Ilias, Stanifer, Megan L., Phillips, Michael A., Paul-Gilloteaux, Perrine, Heiligenstein, Xavier, Wang, Hongchang, Okolo, Chidinma A., Fish, Thomas M., Spink, Matthew C., Stuart, David I., Davis, Ilan, Boulant, Steeve, Grimes, Jonathan M., Dobbie, Ian M., Harkiolaki, Maria
Published in Cell (23.07.2020)
Published in Cell (23.07.2020)
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Structural insights into RNA polymerases of negative-sense RNA viruses
Te Velthuis, Aartjan J W, Grimes, Jonathan M, Fodor, Ervin
Published in Nature reviews. Microbiology (01.05.2021)
Published in Nature reviews. Microbiology (01.05.2021)
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Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Baddock, Hannah T, Brolih, Sanja, Yosaatmadja, Yuliana, Ratnaweera, Malitha, Bielinski, Marcin, Swift, Lonnie P, Cruz-Migoni, Abimael, Fan, Haitian, Keown, Jeremy R, Walker, Alexander P, Morris, Garrett M, Grimes, Jonathan M, Fodor, Ervin, Schofield, Christopher J, Gileadi, Opher, McHugh, Peter J
Published in Nucleic acids research (22.02.2022)
Published in Nucleic acids research (22.02.2022)
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Structures of influenza A virus RNA polymerase offer insight into viral genome replication
Fan, Haitian, Walker, Alexander P, Carrique, Loïc, Keown, Jeremy R, Serna Martin, Itziar, Karia, Dimple, Sharps, Jane, Hengrung, Narin, Pardon, Els, Steyaert, Jan, Grimes, Jonathan M, Fodor, Ervin
Published in Nature (London) (01.09.2019)
Published in Nature (London) (01.09.2019)
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Journal Article
The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure
Martin, Baptiste, Coutard, Bruno, Guez, Théo, Paesen, Guido C, Canard, Bruno, Debart, Françoise, Vasseur, Jean-Jacques, Grimes, Jonathan M, Decroly, Etienne
Published in Nucleic Acids Research (06.09.2018)
Published in Nucleic Acids Research (06.09.2018)
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Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus
Leyrat, Cedric, Renner, Max, Harlos, Karl, Huiskonen, Juha T., Grimes, Jonathan M.
Published in Structure (London) (07.01.2014)
Published in Structure (London) (07.01.2014)
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A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus
Dejnirattisai, Wanwisa, Wongwiwat, Wiyada, Supasa, Sunpetchuda, Zhang, Xiaokang, Dai, Xinghong, Rouvinski, Alexander, Jumnainsong, Amonrat, Edwards, Carolyn, Quyen, Nguyen Than Ha, Duangchinda, Thaneeya, Grimes, Jonathan M, Tsai, Wen-Yang, Lai, Chih-Yun, Wang, Wei-Kung, Malasit, Prida, Farrar, Jeremy, Simmons, Cameron P, Zhou, Z Hong, Rey, Felix A, Mongkolsapaya, Juthathip, Screaton, Gavin R
Published in Nature immunology (01.02.2015)
Published in Nature immunology (01.02.2015)
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Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
Hengrung, Narin, El Omari, Kamel, Serna Martin, Itziar, Vreede, Frank T, Cusack, Stephen, Rambo, Robert P, Vonrhein, Clemens, Bricogne, Gérard, Stuart, David I, Grimes, Jonathan M, Fodor, Ervin
Published in Nature (London) (05.11.2015)
Published in Nature (London) (05.11.2015)
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Journal Article
Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies Its Role in Cell Entry
El Omari, Kamel, Iourin, Oleg, Harlos, Karl, Grimes, Jonathan M., Stuart, David I.
Published in Cell reports (Cambridge) (31.01.2013)
Published in Cell reports (Cambridge) (31.01.2013)
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Structure unifies the viral universe
Abrescia, Nicola G A, Bamford, Dennis H, Grimes, Jonathan M, Stuart, David I
Published in Annual review of biochemistry (01.01.2012)
Published in Annual review of biochemistry (01.01.2012)
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Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample
Keown, Jeremy R, Crawshaw, Adam D, Trincao, Jose, Carrique, Loïc, Gildea, Richard J, Horrell, Sam, Warren, Anna J, Axford, Danny, Owen, Robin, Evans, Gwyndaf, Bézier, Annie, Metcalf, Peter, Grimes, Jonathan M
Published in Nature communications (13.07.2023)
Published in Nature communications (13.07.2023)
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Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II
Keown, Jeremy, Baazaoui, Alaa, Šebesta, Marek, Štefl, Richard, Carrique, Loïc, Fodor, Ervin, Grimes, Jonathan M
Published in Journal of virology (14.05.2024)
Published in Journal of virology (14.05.2024)
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Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation
Staller, Ecco, Carrique, Loïc, Swann, Olivia C, Fan, Haitian, Keown, Jeremy R, Sheppard, Carol M, Barclay, Wendy S, Grimes, Jonathan M, Fodor, Ervin
Published in Nature communications (15.05.2024)
Published in Nature communications (15.05.2024)
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