ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling
Harris, Abigail, Siggers, Pam, Corrochano, Silvia, Warr, Nick, Sagar, Danielle, Grimes, Daniel T., Suzuki, Makoto, Burdine, Rebecca D., Cong, Feng, Koo, Bon-Kyoung, Clevers, Hans, Stévant, Isabelle, Nef, Serge, Wells, Sara, Brauner, Raja, Rhouma, Bochra Ben, Belguith, Neïla, Eozenou, Caroline, Bignon-Topalovic, Joelle, Bashamboo, Anu, McElreavey, Ken, Greenfield, Andy
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2018)
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Journal Article
Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination
Grimes, Daniel T, Keynton, Jennifer L, Buenavista, Maria T, Jin, Xingjian, Patel, Saloni H, Kyosuke, Shinohara, Vibert, Jennifer, Williams, Debbie J, Hamada, Hiroshi, Hussain, Rohanah, Nauli, Surya M, Norris, Dominic P
Published in PLoS genetics (06.06.2016)
Published in PLoS genetics (06.06.2016)
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Journal Article
Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model
Walker, Rebecca V., Keynton, Jennifer L., Grimes, Daniel T., Sreekumar, Vrinda, Williams, Debbie J., Esapa, Chris, Wu, Dongsheng, Knight, Martin M., Norris, Dominic P.
Published in Nature communications (06.09.2019)
Published in Nature communications (06.09.2019)
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Journal Article
c21orf59/kurly Controls Both Cilia Motility and Polarization
Jaffe, Kimberly M., Grimes, Daniel T., Schottenfeld-Roames, Jodi, Werner, Michael E., Ku, Tse-Shuen J., Kim, Sun K., Pelliccia, Jose L., Morante, Nicholas F.C., Mitchell, Brian J., Burdine, Rebecca D.
Published in Cell reports (Cambridge) (01.03.2016)
Published in Cell reports (Cambridge) (01.03.2016)
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Journal Article
Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish
Grimes, Daniel T., Patterson, Victoria L., Luna-Arvizu, Gabriel, Schottenfeld-Roames, Jodi, Irons, Zoe H., Burdine, Rebecca D.
Published in Developmental biology (15.03.2020)
Published in Developmental biology (15.03.2020)
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Journal Article
Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology
Bearce, Elizabeth A, Irons, Zoe H, O'Hara-Smith, Johnathan R, Kuhns, Colin J, Fisher, Sophie I, Crow, William E, Grimes, Daniel T
Published in eLife (01.12.2022)
Published in eLife (01.12.2022)
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Journal Article
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2
Field, Sarah, Riley, Kerry-Lyn, Grimes, Daniel T, Hilton, Helen, Simon, Michelle, Powles-Glover, Nicola, Siggers, Pam, Bogani, Debora, Greenfield, Andy, Norris, Dominic P
Published in Development (Cambridge) (15.03.2011)
Published in Development (Cambridge) (15.03.2011)
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Journal Article
Antagonistic interactions in the zebrafish midline prior to the emergence of asymmetric gene expression are important for left–right patterning
Burdine, Rebecca D., Grimes, Daniel T.
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
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Journal Article
Daw1 regulates the timely onset of cilia motility during development
Bearce, Elizabeth A, Irons, Zoe H, Craig, Samuel B, Kuhns, Colin J, Sabazali, Cynthia, Farnsworth, Dylan R, Miller, Adam C, Grimes, Daniel T
Published in Development (Cambridge) (15.06.2022)
Published in Development (Cambridge) (15.06.2022)
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Journal Article
Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities
Leslie, Joseph S., Hjeij, Rim, Vivante, Asaf, Bearce, Elizabeth A., Dyer, Laura, Wang, Jiaolong, Rawlins, Lettie, Kennedy, Joanna, Ubeyratna, Nishanka, Fasham, James, Irons, Zoe H., Craig, Samuel B., Koenig, Julia, George, Sebastian, Pode-Shakked, Ben, Bolkier, Yoav, Barel, Ortal, Mane, Shrikant, Frederiksen, Kathrine K., Wenger, Olivia, Scott, Ethan, Cross, Harold E., Lorentzen, Esben, Norris, Dominic P., Anikster, Yair, Omran, Heymut, Grimes, Daniel T., Crosby, Andrew H., Baple, Emma L.
Published in Genetics in medicine (01.11.2022)
Published in Genetics in medicine (01.11.2022)
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Journal Article
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis
Goggolidou, Paraskevi, Stevens, Jonathan L, Agueci, Francesco, Keynton, Jennifer, Wheway, Gabrielle, Grimes, Daniel T, Patel, Saloni H, Hilton, Helen, Morthorst, Stine K, DiPaolo, Antonella, Williams, Debbie J, Sanderson, Jeremy, Khoronenkova, Svetlana V, Powles-Glover, Nicola, Ermakov, Alexander, Esapa, Chris T, Romero, Rosario, Dianov, Grigory L, Briscoe, James, Johnson, Colin A, Pedersen, Lotte B, Norris, Dominic P
Published in Development (Cambridge) (01.10.2014)
Published in Development (Cambridge) (01.10.2014)
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Journal Article
Cilia Discern Left from Right
Norris, Dominic P., Grimes, Daniel T.
Published in Science (American Association for the Advancement of Science) (12.10.2012)
Published in Science (American Association for the Advancement of Science) (12.10.2012)
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Journal Article
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway
Patterson, Victoria L., Damrau, Christine, Paudyal, Anju, Reeve, Benjamin, Grimes, Daniel T., Stewart, Michelle E., Williams, Debbie J., Siggers, Pam, Greenfield, Andy, Murdoch, Jennifer N.
Published in Human molecular genetics (15.05.2009)
Published in Human molecular genetics (15.05.2009)
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