Mutations of the Thyroid Hormone Transporter MCT8 Cause Prenatal Brain Damage and Persistent Hypomyelination
López-Espíndola, Daniela, Morales-Bastos, Carmen, Grijota-Martínez, Carmen, Liao, Xiao-Hui, Lev, Dorit, Sugo, Ella, Verge, Charles F, Refetoff, Samuel, Bernal, Juan, Guadaño-Ferraz, Ana
Published in The journal of clinical endocrinology and metabolism (01.12.2014)
Published in The journal of clinical endocrinology and metabolism (01.12.2014)
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Journal Article
Adult Mice Lacking Mct8 and Dio2 Proteins Present Alterations in Peripheral Thyroid Hormone Levels and Severe Brain and Motor Skill Impairments
Bárez-López, Soledad, Grijota-Martínez, Carmen, Ausó, Eva, Fernández-de Frutos, Mario, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana
Published in Thyroid (New York, N.Y.) (01.11.2019)
Published in Thyroid (New York, N.Y.) (01.11.2019)
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Journal Article
Thyroid Hormone-Regulated Mouse Cerebral Cortex Genes Are Differentially Dependent on the Source of the Hormone: A Study in Monocarboxylate Transporter-8- and Deiodinase-2-Deficient Mice
Morte, Beatriz, Ceballos, Ainhoa, Diez, Diego, Grijota-Martínez, Carmen, Dumitrescu, Alexandra M, Di Cosmo, Caterina, Galton, Valerie Anne, Refetoff, Samuel, Bernal, Juan
Published in Endocrinology (Philadelphia) (01.05.2010)
Published in Endocrinology (Philadelphia) (01.05.2010)
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Journal Article
A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations
Valcárcel-Hernández, Víctor, Guillén-Yunta, Marina, Bueno-Arribas, Miranda, Montero-Pedrazuela, Ana, Grijota-Martínez, Carmen, Markossian, Suzy, García-Aldea, Ángel, Flamant, Frédéric, Bárez-López, Soledad, Guadaño-Ferraz, Ana
Published in Neurobiology of disease (01.11.2022)
Published in Neurobiology of disease (01.11.2022)
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Defective thyroid hormone transport to the brain leads to astroglial alterations
Guillén-Yunta, Marina, García-Aldea, Ángel, Valcárcel-Hernández, Víctor, Sanz-Bógalo, Ainara, Muñoz-Moreno, Emma, Matheus, Maria Gisele, Grijota-Martínez, Carmen, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Bárez-López, Soledad
Published in Neurobiology of disease (01.10.2024)
Published in Neurobiology of disease (01.10.2024)
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Journal Article
Intranasal delivery of Thyroid hormones in MCT8 deficiency
Grijota-Martínez, Carmen, Bárez-López, Soledad, Ausó, Eva, Refetoff, Samuel, Frey, 2nd, William H, Guadaño-Ferraz, Ana
Published in PloS one (20.07.2020)
Published in PloS one (20.07.2020)
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Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis
Rial-Pensado, Eva, Rivas-Limeres, Verónica, Grijota-Martínez, Carmen, Rodríguez-Díaz, Amanda, Capelli, Valentina, Barca-Mayo, Olga, Nogueiras, Rubén, Mittag, Jens, Diéguez, Carlos, López, Miguel
Published in Frontiers in physiology (18.11.2022)
Published in Frontiers in physiology (18.11.2022)
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Journal Article
Orally Induced Hyperthyroidism Regulates Hypothalamic AMP-Activated Protein Kinase
Capelli, Valentina, Grijota-Martínez, Carmen, Dragano, Nathalia R V, Rial-Pensado, Eval, Fernø, Johan, Nogueiras, Rubén, Mittag, Jens, Diéguez, Carlos, López, Miguel
Published in Nutrients (24.11.2021)
Published in Nutrients (24.11.2021)
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Journal Article
Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8)
Rodrigues, Tiago B, Ceballos, Ainhoa, Grijota-Martínez, Carmen, Nuñez, Barbara, Refetoff, Samuel, Cerdán, Sebastian, Morte, Beatriz, Bernal, Juan
Published in PloS one (01.10.2013)
Published in PloS one (01.10.2013)
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Journal Article
Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila
Velasquez, Emma, Gomez-Sanchez, Jose A, Donier, Emmanuelle, Grijota-Martinez, Carmen, Cabedo, Hugo, Garcia-Alonso, Luis
Published in PLoS genetics (01.06.2022)
Published in PLoS genetics (01.06.2022)
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Journal Article
MCT8 Deficiency: The Road to Therapies for a Rare Disease
Grijota-Martínez, Carmen, Bárez-López, Soledad, Gómez-Andrés, David, Guadaño-Ferraz, Ana
Published in Frontiers in neuroscience (28.04.2020)
Published in Frontiers in neuroscience (28.04.2020)
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Journal Article
Thyroid Hormone Regulation of Gene Expression in the Developing Rat Fetal Cerebral Cortex: Prominent Role of the Ca2+/Calmodulin-Dependent Protein Kinase IV Pathway
Morte, Beatriz, Díez, Diego, Ausó, Eva, Belinchón, Mónica M, Gil-Ibáñez, Pilar, Grijota-Martínez, Carmen, Navarro, Daniela, Morreale de Escobar, Gabriella, Berbel, Pere, Bernal, Juan
Published in Endocrinology (Philadelphia) (01.02.2010)
Published in Endocrinology (Philadelphia) (01.02.2010)
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Intracerebroventricular High Doses of 3,3',5-Triiodothyroacetic Acid at Juvenile Stages Improve Peripheral Hyperthyroidism and Mediate Thyromimetic Effects in Limited Brain Regions in a Mouse Model of Monocarboxylate Transporter 8 Deficiency
Grijota-Martínez, Carmen, Montero-Pedrazuela, Ana, Hidalgo-Álvarez, Jorge, Bárez-López, Soledad, Guadaño-Ferraz, Ana
Published in Thyroid (New York, N.Y.) (01.04.2023)
Published in Thyroid (New York, N.Y.) (01.04.2023)
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Journal Article
BMP8 and activated brown adipose tissue in human newborns
Urisarri, Adela, González-García, Ismael, Estévez-Salguero, Ánxela, Pata, María P., Milbank, Edward, López, Noemi, Mandiá, Natalia, Grijota-Martinez, Carmen, Salgado, Carlos A., Nogueiras, Rubén, Diéguez, Carlos, Villarroya, Francesc, Fernández-Real, José-Manuel, Couce, María L., López, Miguel
Published in Nature communications (06.09.2021)
Published in Nature communications (06.09.2021)
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Journal Article
Lack of Action of Exogenously Administered T3 on the Fetal Rat Brain Despite Expression of the Monocarboxylate Transporter 8
Grijota-Martínez, Carmen, Díez, Diego, Morreale de Escobar, Gabriella, Bernal, Juan, Morte, Beatriz
Published in Endocrinology (Philadelphia) (01.04.2011)
Published in Endocrinology (Philadelphia) (01.04.2011)
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Journal Article
Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction
Neves, João Sérgio, Leite, Ana Rita, Conceição, Glória, Gonçalves, Alexandre, Borges-Canha, Marta, Vale, Catarina, Von-Hafe, Madalena, Martins, Diana, Miranda-Silva, Daniela, Leite, Sara, Rocha-Oliveira, Estela, Sousa-Mendes, Cláudia, Chaves, Joana, Lourenço, Inês Mariana, Grijota-Martínez, Carmen, Bárez-López, Soledad, Miranda, Isabel M, Almeida-Coelho, João, Vasques-Nóvoa, Francisco, Carvalho, Davide, Lourenço, André, Falcão-Pires, Inês, Leite-Moreira, Adelino
Published in Thyroid (New York, N.Y.) (01.08.2023)
Published in Thyroid (New York, N.Y.) (01.08.2023)
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Journal Article
Importance of Monocarboxylate Transporter 8 for the Blood-Brain Barrier-Dependent Availability of 3,5,3′-Triiodo-l-Thyronine
Ceballos, Ainhoa, Belinchon, Monica M, Sanchez-Mendoza, Eduardo, Grijota-Martinez, Carmen, Dumitrescu, Alexandra M, Refetoff, Samuel, Morte, Beatriz, Bernal, Juan
Published in Endocrinology (Philadelphia) (01.05.2009)
Published in Endocrinology (Philadelphia) (01.05.2009)
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