Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
Nave, Klaus-Armin, Lappe-Siefke, Corinna, Goebbels, Sandra, Gravel, Michel, Nicksch, Eva, Lee, John, Braun, Peter E, Griffiths, Ian R
Published in Nature genetics (01.03.2003)
Published in Nature genetics (01.03.2003)
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Oligodendroglial Modulation of Fast Axonal Transport in a Mouse Model of Hereditary Spastic Paraplegia
Edgar, Julia M., McLaughlin, Mark, Yool, Donald, Zhang, Su-Chun, Fowler, Jill H., Montague, Paul, Barrie, Jennifer A., McCulloch, Mailis C., Duncan, Ian D., Garbern, James, Nave, Klaus A., Griffiths, Ian R.
Published in The Journal of cell biology (05.07.2004)
Published in The Journal of cell biology (05.07.2004)
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Journal Article
Myelinated, synapsing cultures of murine spinal cord - validation as an in vitro model of the central nervous system
Thomson, C. E., McCulloch, M., Sorenson, A., Barnett, S. C., Seed, B. V., Griffiths, I. R., McLaughlin, M.
Published in The European journal of neuroscience (01.10.2008)
Published in The European journal of neuroscience (01.10.2008)
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Journal Article
Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation
GARBERN, James Y, YOOL, Donald A, SHY, Michael E, KAMHOLZ, John A, GRIFFITHS, Ian R, MOORE, Gregory J, WILDS, Ian B, FAULK, Michael W, KLUGMANN, Matthias, NAVE, Klaus-Amin, SISTERMANS, Erik A, VAN DER KNAAP, Marjo S, BIRD, Thomas D
Published in Brain (London, England : 1878) (01.03.2002)
Published in Brain (London, England : 1878) (01.03.2002)
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Journal Article
Assembly of CNS Myelin in the Absence of Proteolipid Protein
Klugmann, Matthias, Schwab, Markus H., Pühlhofer, Anja, Schneider, Armin, Zimmermann, Frank, Griffiths, Ian R., Nave, Klaus-Armin
Published in Neuron (Cambridge, Mass.) (01.01.1997)
Published in Neuron (Cambridge, Mass.) (01.01.1997)
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Journal Article
Peripheral Demyelination and Neuropathic Pain Behavior in Periaxin-Deficient Mice
Gillespie, C.Stewart, Sherman, Diane L., Fleetwood-Walker, Susan M., Cottrell, David F., Tait, Steven, Garry, Emer M., Wallace, Victoria C.J., Ure, Jan, Griffiths, Ian R., Smith, Austin, Brophy, Peter J.
Published in Neuron (Cambridge, Mass.) (01.05.2000)
Published in Neuron (Cambridge, Mass.) (01.05.2000)
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Journal Article
Genetic background influences UPR but not PLP processing in the rumpshaker model of PMD/SPG2
McLaughlin, M, Karim, S A, Montague, P, Barrie, J A, Kirkham, D, Griffiths, I R, Edgar, J M
Published in Neurochemical research (01.02.2007)
Published in Neurochemical research (01.02.2007)
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Journal Article
Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation
McLaughlin, Mark, Barrie, Jennifer A., Karim, Saadia, Montague, Paul, Edgar, Julia M., Kirkham, Douglas, Thomson, Christine E., Griffiths, Ian R
Published in Glia (01.05.2006)
Published in Glia (01.05.2006)
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Journal Article
Late-onset neurodegeneration in mice with increased dosage of the proteolipid protein gene
Anderson, T.J., Schneider, A., Barrie, J.A., Klugmann, M., McCulloch, M.C., Kirkham, D., Kyriakides, E., Nave, K.-A., Griffiths, I.R.
Published in Journal of comparative neurology (1911) (18.05.1998)
Published in Journal of comparative neurology (1911) (18.05.1998)
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Journal Article
Genetic background determines phenotypic severity of the Plp rumpshaker mutation
Al-Saktawi, K., McLaughlin, M., Klugmann, M., Schneider, A., Barrie, J.A., McCulloch, M.C., Montague, P., Kirkham, D., Nave, K.-A., Griffiths, I.R.
Published in Journal of neuroscience research (01.04.2003)
Published in Journal of neuroscience research (01.04.2003)
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Journal Article
Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene
Edgar, J M, McLaughlin, M, Barrie, J A, McCulloch, M C, Garbern, J, Griffiths, I R
Published in Acta neuropathologica (01.04.2004)
Published in Acta neuropathologica (01.04.2004)
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Journal Article
Structure of myelin P2 protein from equine spinal cord
Hunter, Dominic J. B., Macmaster, Rachel, Roszak, Aleksander W., Riboldi-Tunnicliffe, Alan, Griffiths, Ian R., Freer, Andrew A.
Published in Acta crystallographica. Section D, Biological crystallography. (01.08.2005)
Published in Acta crystallographica. Section D, Biological crystallography. (01.08.2005)
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Journal Article
Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons
Yool, D.A., Klugmann, M., McLaughlin, M., Vouyiouklis, D.A., Dimou, L., Barrie, J.A., McCulloch, M.C., Nave, K.-A., Griffiths, I.R.
Published in Journal of neuroscience research (15.01.2001)
Published in Journal of neuroscience research (15.01.2001)
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Journal Article
Oligodendrocytes are not inherently programmed to myelinate a specific size of axon
Fanarraga, M.L., Griffiths, I.R., Zhao, M., Duncan, I.D.
Published in Journal of comparative neurology (1911) (14.09.1998)
Published in Journal of comparative neurology (1911) (14.09.1998)
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Journal Article
Characterization of the murine splice variant Mobp155: Developmental CNS expression pattern and subcellular localization of epitope-tagged protein
Montague, Paul, McCallion, Andrew S., Barrie, Jennifer E., Edgar, Julia M., McLaughlin, Mark, Davies, R. Wayne, Griffiths, Ian R.
Published in Glia (01.04.2005)
Published in Glia (01.04.2005)
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Journal Article
Distinct Phenotypes Associated with Increasing Dosage of the PLP Gene: Implications for CMT1A Due to PMP22 Gene Duplication
Anderson, T J, Klugmann, M, Thomson, C E, Schneider, A, Readhead, C, Nave, K-A, Griffiths, I R
Published in Annals of the New York Academy of Sciences (01.10.1999)
Published in Annals of the New York Academy of Sciences (01.10.1999)
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