Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases
Vazquez, Michael L, Kaila, Neelu, Strohbach, Joseph W, Trzupek, John D, Brown, Matthew F, Flanagan, Mark E, Mitton-Fry, Mark J, Johnson, Timothy A, TenBrink, Ruth E, Arnold, Eric P, Basak, Arindrajit, Heasley, Steven E, Kwon, Soojin, Langille, Jonathan, Parikh, Mihir D, Griffin, Sarah H, Casavant, Jeffrey M, Duclos, Brian A, Fenwick, Ashley E, Harris, Thomas M, Han, Seungil, Caspers, Nicole, Dowty, Martin E, Yang, Xin, Banker, Mary Ellen, Hegen, Martin, Symanowicz, Peter T, Li, Li, Wang, Lu, Lin, Tsung H, Jussif, Jason, Clark, James D, Telliez, Jean-Baptiste, Robinson, Ralph P, Unwalla, Ray
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Published in Journal of medicinal chemistry (08.02.2018)
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Development of a Nitrene-Type Rearrangement for the Commercial Route of the JAK1 Inhibitor Abrocitinib
Connor, Christina G, DeForest, Jacob C, Dietrich, Phil, Do, Nga M, Doyle, Kevin M, Eisenbeis, Shane, Greenberg, Elizabeth, Griffin, Sarah H, Jones, Brian P, Jones, Kris N, Karmilowicz, Michael, Kumar, Rajesh, Lewis, Chad A, McInturff, Emma L, McWilliams, J. Christopher, Mehta, Ruchi, Nguyen, Bao D, Rane, Anil M, Samas, Brian, Sitter, Barbara J, Ward, Howard W, Webster, Mark E
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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