Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex
Andersen, Jens V., Westi, Emil W., Griem‐Krey, Nane, Skotte, Niels H., Schousboe, Arne, Aldana, Blanca I., Wellendorph, Petrine
Published in Journal of neurochemistry (01.05.2024)
Published in Journal of neurochemistry (01.05.2024)
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GABAA receptor β1‐subunit knock‐out mice show increased delta power in NREM sleep and decreased theta power in REM sleep
Lie, Maria Elena Klibo, Falk‐Petersen, Christina Birkedahl, Piilgaard, Louise, Griem‐Krey, Nane, Wellendorph, Petrine, Kornum, Birgitte Rahbek, Adamantidis, Antoine
Published in The European journal of neuroscience (01.07.2021)
Published in The European journal of neuroscience (01.07.2021)
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Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity
Narayanan, Dilip, Larsen, Anne Sofie G., Gauger, Stine Juul, Adafia, Ruth, Hammershøi, Rikke Bartschick, Hamborg, Louise, Bruus‐Jensen, Jesper, Griem‐Krey, Nane, Gee, Christine L., Frølund, Bente, Stratton, Margaret M., Kuriyan, John, Kastrup, Jette Sandholm, Langkilde, Annette E., Wellendorph, Petrine, Solbak, Sara M. Ø.
Published in Protein science (01.10.2024)
Published in Protein science (01.10.2024)
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GABA A receptor β 1 -subunit knock-out mice show increased delta power in NREM sleep and decreased theta power in REM sleep
Lie, Maria Elena Klibo, Falk-Petersen, Christina Birkedahl, Piilgaard, Louise, Griem-Krey, Nane, Wellendorph, Petrine, Kornum, Birgitte Rahbek
Published in The European journal of neuroscience (01.07.2021)
Published in The European journal of neuroscience (01.07.2021)
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The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction
Griem-Krey, Nane, Gauger, Stine J., Gowing, Emma K., Thiesen, Louise, Frølund, Bente, Clarkson, Andrew N., Wellendorph, Petrine
Published in Biomedicine & pharmacotherapy (01.12.2022)
Published in Biomedicine & pharmacotherapy (01.12.2022)
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Synthesis and Pharmacological Evaluation of [11C]4-Methoxy‑N‑[2-(thiophen-2-yl)imidazo[1,2‑a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ‑Subunit-Containing γ‑Aminobutyric Acid Type A Receptors
L’Estrade, Elina T, Hansen, Hanne D, Falk-Petersen, Christina, Haugaard, Anne, Griem-Krey, Nane, Jung, Sascha, Lüddens, Hartmut, Schirmeister, Tanja, Erlandsson, Maria, Ohlsson, Tomas, Knudsen, Gitte M, Herth, Matthias M, Wellendorph, Petrine, Frølund, Bente
Published in ACS omega (31.05.2019)
Published in ACS omega (31.05.2019)
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The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4
Thiesen, Louise, Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Falsig, Crocoll, Christoph, Nour-Eldin, Hussam Hassan, Wellendorph, Petrine
Published in European journal of pharmaceutical sciences (15.02.2020)
Published in European journal of pharmaceutical sciences (15.02.2020)
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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
Leurs, Ulrike, Klein, Anders B., McSpadden, Ethan D., Griem-Krey, Nane, Solbak, Sara M. Ø., Houlton, Josh, Villumsen, Inge S., Vogensen, Stine B., Hamborg, Louise, Gauger, Stine J., Palmelund, Line B., Larsen, Anne Sofie G., Shehata, Mohamed A., Kelstrup, Christian D., Olsen, Jesper V., Bach, Anders, Burnie, Robert O., Kerr, D. Steven, Gowing, Emma K., Teurlings, Selina M. W., Chi, Chris C., Gee, Christine L., Frølund, Bente, Kornum, Birgitte R., van Woerden, Geeske M., Clausen, Rasmus P., Kuriyan, John, Clarkson, Andrew N., Wellendorph, Petrine
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2021)
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The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα
Griem-Krey, Nane, Klein, Anders B, Clausen, Bettina H, Namini, Mathias RJ, Nielsen, Pernille V, Bhuiyan, Mozammel, Nagaraja, Raghavendra Y, De Silva, T Michael, Sobey, Christopher G, Cheng, Heung-Chin, Orset, Cyrille, Vivien, Denis, Lambertsen, Kate L, Clarkson, Andrew N, Wellendorph, Petrine
Published in Journal of cerebral blood flow and metabolism (01.08.2023)
Published in Journal of cerebral blood flow and metabolism (01.08.2023)
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N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection
Ameen, S. Sadia, Griem-Krey, Nane, Dufour, Antoine, Hossain, M. Iqbal, Hoque, Ashfaqul, Sturgeon, Sharelle, Nandurkar, Harshal, Draxler, Dominik F., Medcalf, Robert L., Kamaruddin, Mohd Aizuddin, Lucet, Isabelle S., Leeming, Michael G., Liu, Dazhi, Dhillon, Amardeep, Lim, Jet Phey, Basheer, Faiza, Zhu, Hong-Jian, Bokhari, Laita, Roulston, Carli L., Paradkar, Prasad N., Kleifeld, Oded, Clarkson, Andrew N., Wellendorph, Petrine, Ciccotosto, Giuseppe D., Williamson, Nicholas A., Ang, Ching-Seng, Cheng, Heung-Chin
Published in Molecular & cellular proteomics (01.05.2023)
Published in Molecular & cellular proteomics (01.05.2023)
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The GHB analogue HOCPCA improves sensorimotor function after MCAO via CaMKIIα
Griem-Krey, Nane, Anders Bue Klein, Bettina Hjelm Clausen, Namini, Mathias Rj, Nielsen, Pernille Vinther, Chin-Cheng, Heung, Orset, Cyrille, Denis, Vivien, Clarkson, Andrew N, Lambertsen, Kate L, Wellendorph, Petrine
Published in bioRxiv (12.03.2022)
Published in bioRxiv (12.03.2022)
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N-Terminomic Changes of Neurons During Excitotoxicity Reveals Proteolytic Events Associated with Synaptic Dysfunctions and Potential Targets for Neuroprotection
S Sadia Ameen, Griem-Krey, Nane, Dufour, Antoine, M Iqbal Hossain, Hoque, Ashfaqul, Sturgeon, Sharelle, Nandurkar, Harshal, Draxler, Dominik F, Medcalf, Robert L, Kamaruddin, Mohd Aizuddin, Lucet, Isabelle S, Leeming, Michael G, Liu, Dazhi, Dhillon, Amardeep, Lim, Jet Phey, Basheer, Faiza, Hong-Jian, Zhu, Bokhari, Laita, Roulston, Carli, Paradkar, Prasad N, Kleifeld, Oded, Clarkson, Andrew N, Wellendorph, Petrine, Ciccotosto, Giuseppe D, Williamson, Nicholas A, Ching-Seng Ang, Heung-Chin, Cheng
Published in bioRxiv (14.03.2022)
Published in bioRxiv (14.03.2022)
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GHB confers neuroprotection by stabilizing the CaMKIIα hub domain
Leurs, Ulrike, Klein, Anders B, Mcspadden, Ethan D, Griem-Krey, Nane, Sara M Ø Solbak, Houlton, Josh, Villumsen, Inge S, Vogensen, Stine B, Hamborg, Louise, Gauger, Stine J, Palmelund, Line B, Larsen, Anne Sofie G, Shehata, Mohamed A, Kelstrup, Christian D, Olsen, Jesper V, Bach, Anders, Burnie, Robert O, Kerr, D Steven, Gowing, Emma K, Teurlings, Selina M W, Chi, Chris C, Gee, Christine L, Frølund, Bente, Kornum, Birgitte R, Van Woerden, Geeske M, Clausen, Rasmus P, Kuriyan, John, Clarkson, Andrew N, Wellendorph, Petrine
Published in bioRxiv (28.09.2020)
Published in bioRxiv (28.09.2020)
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