LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML
Barth, Jessica, Abou-El-Ardat, Khalil, Dalic, Denis, Kurrle, Nina, Maier, Anna-Maria, Mohr, Sebastian, Schütte, Judith, Vassen, Lothar, Greve, Gabriele, Schulz-Fincke, Johannes, Schmitt, Martin, Tosic, Milica, Metzger, Eric, Bug, Gesine, Khandanpour, Cyrus, Wagner, Sebastian A., Lübbert, Michael, Jung, Manfred, Serve, Hubert, Schüle, Roland, Berg, Tobias
Published in Leukemia (01.06.2019)
Published in Leukemia (01.06.2019)
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The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells
Greve, Gabriele, Schiffmann, Insa, Pfeifer, Dietmar, Pantic, Milena, Schüler, Julia, Lübbert, Michael
Published in BMC cancer (16.12.2015)
Published in BMC cancer (16.12.2015)
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Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation
Schulz-Fincke, Johannes, Hau, Mirjam, Barth, Jessica, Robaa, Dina, Willmann, Dominica, Kürner, Andreas, Haas, Julian, Greve, Gabriele, Haydn, Tinka, Fulda, Simone, Lübbert, Michael, Lüdeke, Steffen, Berg, Tobias, Sippl, Wolfgang, Schüle, Roland, Jung, Manfred
Published in European journal of medicinal chemistry (20.01.2018)
Published in European journal of medicinal chemistry (20.01.2018)
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The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation
Meier, Ruth, Greve, Gabriele, Zimmer, Dennis, Bresser, Helena, Berberich, Bettina, Langova, Ralitsa, Stomper, Julia, Rubarth, Anne, Feuerbach, Lars, Lipka, Daniel B., Hey, Joschka, Grüning, Björn, Brors, Benedikt, Duyster, Justus, Plass, Christoph, Becker, Heiko, Lübbert, Michael
Published in Blood cancer journal (New York) (22.08.2022)
Published in Blood cancer journal (New York) (22.08.2022)
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Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML
Barth, Jessica, Abou-El-Ardat, Khalil, Dalic, Denis, Kurrle, Nina, Maier, Anna-Maria, Mohr, Sebastian, Schütte, Judith, Vassen, Lothar, Greve, Gabriele, Schulz-Fincke, Johannes, Schmitt, Martin, Tosic, Milica, Metzger, Eric, Bug, Gesine, Khandanpour, Cyrus, Wagner, Sebastian A., Lübbert, Michael, Jung, Manfred, Serve, Hubert, Schüle, Roland, Berg, Tobias
Published in Leukemia (01.06.2019)
Published in Leukemia (01.06.2019)
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Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat
Blagitko-Dorfs, Nadja, Jiang, Yi, Duque-Afonso, Jesús, Hiller, Jan, Yalcin, Arzu, Greve, Gabriele, Abdelkarim, Mahmoud, Hackanson, Björn, Lübbert, Michael
Published in PloS one (08.10.2013)
Published in PloS one (08.10.2013)
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Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia
Becker, Heiko, Greve, Gabriele, Kataoka, Keisuke, Mallm, Jan-Philipp, Duque-Afonso, Jesús, Ma, Tobias, Niemöller, Christoph, Pantic, Milena, Duyster, Justus, Cleary, Michael L., Schüler, Julia, Rippe, Karsten, Ogawa, Seishi, Lübbert, Michael
Published in Blood advances (12.03.2019)
Published in Blood advances (12.03.2019)
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Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives
Schiffmann, Insa, Greve, Gabriele, Jung, Manfred, Lübbert, Michael
Published in Epigenetics (01.12.2016)
Published in Epigenetics (01.12.2016)
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Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation
Blagitko-Dorfs, Nadja, Schlosser, Pascal, Greve, Gabriele, Pfeifer, Dietmar, Meier, Ruth, Baude, Annika, Brocks, David, Plass, Christoph, Lübbert, Michael
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Identification of Epigenetic Modifiers Essential for Growth and Survival of AML1/ETO-Positive Leukemia
Duque Afonso, Jesus, Pia, Veratti, Rehman, Usama-Ur, Herzog, Heike, Mitschke, Jan, Greve, Gabriele, Eble, Julian, Berberich, Bettina, Thomas, Johanna, Pantic, Milena, Waterhouse, Miguel, Gentile, Gaia, Heidenreich, Olaf, Miething, Cornelius, Lübbert, Michael
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Identification of epigenetic modifiers essential for growth and survival of AML1/ETO‐positive leukemia
Duque‐Afonso, Jesús, Veratti, Pia, Rehman, Usama‐Ur, Herzog, Heike, Mitschke, Jan, Greve, Gabriele, Eble, Julian, Berberich, Bettina, Thomas, Johanna, Pantic, Milena, Waterhouse, Miguel, Gentile, Gaia, Heidenreich, Olaf, Miething, Cornelius, Lübbert, Michael
Published in International journal of cancer (01.12.2024)
Published in International journal of cancer (01.12.2024)
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Decitabine Induces Gene Derepression on Monosomic Chromosomes: In Vitro and In Vivo Effects in Adverse-Risk Cytogenetics AML
Greve, Gabriele, Schüler, Julia, Grüning, Björn A, Berberich, Bettina, Stomper, Julia, Zimmer, Dennis, Gutenkunst, Lea, Bönisch, Ulrike, Meier, Ruth, Blagitko-Dorfs, Nadja, Grishina, Olga, Pfeifer, Dietmar, Weichenhan, Dieter, Plass, Christoph, Lübbert, Michael
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All-Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)
Hund, Inga, Hess, Maria, Stomper, Julia, Greve, Gabriele, Mitschke, Jan, Niemöller, Christoph, Ma, Tobias, Uhl, David, Thol, Felicitas R., Heuser, Michael, Bug, Gesine, Crysandt, Martina, Mueller, Lutz Peter, Neubauer, Andreas, Duyster, Justus, Dohner, Hartmut, Boerries, Melanie, Becker, Heiko, Luebbert, Michael
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Innovative strategies for adverse karyotype acute myeloid leukemia
Blum, Sabine, Greve, Gabriele, Lübbert, Michael
Published in Current opinion in hematology (01.03.2017)
Published in Current opinion in hematology (01.03.2017)
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