Candidate Selection and Preclinical Evaluation of N-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century
O’Neill, Paul M, Park, B. Kevin, Shone, Alison E, Maggs, James L, Roberts, Phillip, Stocks, Paul A, Biagini, Giancarlo A, Bray, Patrick G, Gibbons, Peter, Berry, Neil, Winstanley, Peter A, Mukhtar, Amira, Bonar-Law, Richard, Hindley, Stephen, Bambal, Ramesh B, Davis, Charles B, Bates, Martin, Hart, Timothy K, Gresham, Stephanie L, Lawrence, Ron M, Brigandi, Richard A, Gomez-delas-Heras, Federico M, Gargallo, Domingo V, Ward, Stephen A
Published in Journal of medicinal chemistry (12.03.2009)
Published in Journal of medicinal chemistry (12.03.2009)
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Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine
O’Neill, Paul M, Shone, Alison E, Stanford, Deborah, Nixon, Gemma, Asadollahy, Eghbaleh, Park, B. Kevin, Maggs, James L, Roberts, Phil, Stocks, Paul A, Biagini, Giancarlo, Bray, Patrick G, Davies, Jill, Berry, Neil, Hall, Charlotte, Rimmer, Karen, Winstanley, Peter A, Hindley, Stephen, Bambal, Ramesh B, Davis, Charles B, Bates, Martin, Gresham, Stephanie L, Brigandi, Richard A, Gomez-de-las-Heras, Federico M, Gargallo, Domingo V, Parapini, Silvia, Vivas, Livia, Lander, Hollie, Taramelli, Donatella, Ward, Stephen A
Published in Journal of medicinal chemistry (09.04.2009)
Published in Journal of medicinal chemistry (09.04.2009)
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Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Albrecht, Sébastian, Álvarez-Pedraglio, Ana Isabel, Boesche, Markus, Brand, Stephen, Campbell, Lorna, Cantizani-Perez, Juan, Cleghorn, Laura A.T, Copley, Royston C.B, Crouch, Sabrinia D, Daugan, Alain, Drewes, Gerard, Ferrer, Santiago, Ghidelli-Disse, Sonja, Gonzalez, Silvia, Gresham, Stephanie L, Hill, Alan P, Hindley, Sean J, Lowe, Rhiannon M, MacKenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Miguel-Siles, Juan, Nguyen, Van Loc, Norval, Suzanne, Osuna-Cabello, Maria, Woodland, Andrew, Patterson, Stephen, Pena, Imanol, Quesada-Campos, Maria Teresa, Reid, Iain H, Revill, Charlotte, Riley, Jennifer, Ruiz-Gomez, Jose Ramon, Shishikura, Yoko, Simeons, Frederick R.C, Smith, Alasdair, Smith, Victoria C, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Underwood, Tim, Gray, David W, Fiandor, Jose M, Gilbert, Ian H, Wyatt, Paul G, Read, Kevin D, Miles, Timothy J
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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