Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers
Bolognani, Federico, Kruithof, Annelieke C, Schulthess, Pascal, Machacek, Matthias, de Kam, Marieke L, Bergmann, Kirsten R, van Gent, Max, Moerland, Matthijs, Crenn, Pascal, Greig, Gérard, Gal, Pim
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
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Pharmacokinetics and Tolerability of a Single Dose of Apraglutide, a Novel, Long‐Acting, Synthetic glucagon‐like peptide‐2 Analog With a Unique Pharmacologic Profile, in Individuals With Impaired Renal Function
Greig, Gérard, Youssef, Nader N, Bolognani, Federico
Published in Journal of clinical pharmacology (01.06.2024)
Published in Journal of clinical pharmacology (01.06.2024)
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Test-retest reliability of task-based and resting-state blood oxygen level dependence and cerebral blood flow measures
Holiga, Štefan, Sambataro, Fabio, Luzy, Cécile, Greig, Gérard, Sarkar, Neena, Renken, Remco J, Marsman, Jan-Bernard C, Schobel, Scott A, Bertolino, Alessandro, Dukart, Juergen
Published in PloS one (08.11.2018)
Published in PloS one (08.11.2018)
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Pattern recognition analysis of digital ECGs: Decreased QT measurement error and improved precision compared to semi-automated methods
Meyer, Olivier, MS, Ferber, Georg, PhD, Greig, Gerard, MD, Holzgrefe, Henry H., BA
Published in Journal of electrocardiology (01.03.2013)
Published in Journal of electrocardiology (01.03.2013)
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Su1949 THE EFFECT OF APRAGLUTIDE ON GASTRIC EMPTYING IN HEALTHY INDIVIDUALS: A PHASE 1 RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, SINGLE-CENTER TRIAL
Greig, Gerard, Youssef, Nader N., Li, Carrie, Bolognani, Federico
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
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Su1620: PHARMACOKINETICS AND TOLERABILITY OF A SINGLE DOSE OF APRAGLUTIDE IN SUBJECTS WITH NORMAL AND IMPAIRED RENAL FUNCTION: A PHASE 1, OPEN-LABEL, NON-RANDOMIZED, PARALLELGROUP STUDY
Greig, Gerard, Hurley, Niamh, Michel, Eric, Youssef, Nader N
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Su559 POPULATION MODEL CONFIRMS PREDICTABLE PHARMACOKINETIC (PK) AND PHARMACODYNAMIC (PD) PROFILE FOR APRAGLUTIDE - DATA FROM TWO RANDOMIZED PHASE 1 STUDIES
Bolognani, Federico, Machacek, Matthias, Kruithof, Annelieke, de Kam, Marieke L., Bergmann, Kirsten, van Gent, Max, Moerland, Matthijs, Crenn, Pascal, Meyer, Christian, Greig, Gerard, Gal, Pim, Schulthess, Pascal
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors
Kurzrock, Razelle, Patnaik, Amita, Aisner, Joseph, Warren, Terri, Leong, Stephen, Benjamin, Robert, Eckhardt, S Gail, Eid, Joseph E, Greig, Gerard, Habben, Kai, McCarthy, Cinara D, Gore, Lia
Published in Clinical cancer research (15.04.2010)
Published in Clinical cancer research (15.04.2010)
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Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non-Michaelis-Menten P450 Kinetics on Fraction Metabolized
Fowler, Stephen, Guerini, Elena, Qiu, NaHong, Cleary, Yumi, Parrott, Neil, Greig, Gerard, Mallalieu, Navita L
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
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A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans
Guerini, Elena, Schadt, Simone, Greig, Gerard, Haas, Ruth, Husser, Christophe, Zell, Manfred, Funk, Christoph, Hartung, Thomas, Gloge, Andreas, Mallalieu, Navita L.
Published in Xenobiotica (01.02.2017)
Published in Xenobiotica (01.02.2017)
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QT and QTc interval with standard and supratherapeutic doses of darifenacin, a muscarinic M3 selective receptor antagonist for the treatment of overactive bladder
Serra, Denise B, Affrime, Melton B, Bedigian, Martin P, Greig, Gerard, Milosavljev, Slavica, Skerjanec, Andrej, Wang, Yibin
Published in Journal of clinical pharmacology (01.09.2005)
Published in Journal of clinical pharmacology (01.09.2005)
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Erratum to: Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update
Banholzer, Maria Longauer, Wandel, Christoph, Barrow, Paul, Mannino, Marie, Schmitt, Georg, Guérard, Melanie, Müller, Lutz, Greig, Gerard, Amemiya, Kenjie, Peck, Richard, Singer, Thomas, Doessegger, Lucette
Published in Clinical and translational medicine (01.12.2016)
Published in Clinical and translational medicine (01.12.2016)
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Pimecrolimus Identifies a Common Genomic Anti-inflammatory Profile, is Clinically Highly Effective in Psoriasis and is Well Tolerated
Rappersberger, Klemens, Komar, Michael, Richter, Leo, Wolff, Klaus, Ebelin, Marie-Eve, Scott, Graham, Burtin, Pascale, Greig, Gerard, Kehren, Jeanne, Chibout, Salah-Dine, Cordier, Andre, Holter, Wolfgang, Oberbauer, Rainer, Stuetz, Anton
Published in Journal of investigative dermatology (01.10.2002)
Published in Journal of investigative dermatology (01.10.2002)
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Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update
Banholzer, Maria Longauer, Wandel, Christoph, Barrow, Paul, Mannino, Marie, Schmitt, Georg, Guérard, Melanie, Müller, Lutz, Greig, Gerard, Amemiya, Kenjie, Peck, Richard, Singer, Thomas, Doessegger, Lucette
Published in Clinical and translational medicine (01.12.2016)
Published in Clinical and translational medicine (01.12.2016)
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Pharmacokinetics of licarbazepine in healthy volunteers: single and multiple oral doses and effect of food
Souppart, Claire, Gardin, Anne, Greig, Gerard, Balez, Sebastien, Batard, Yannick, Krebs-Brown, Axel, Appel-Dingemanse, Silke
Published in Journal of clinical pharmacology (01.05.2008)
Published in Journal of clinical pharmacology (01.05.2008)
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TA-46, a recombinant soluble FGFR3 receptor for the treatment of achondroplasia, is safe and well-tolerated in healthy volunteers
Collins, Samuel, Greig, Gerard, Porter, Richard, Stavenhagen, Jeff, Santarelli, Luca, Meyer, Christian
Published in Bone Abstracts (31.07.2019)
Published in Bone Abstracts (31.07.2019)
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Pharmacokinetics of pimecrolimus, a novel nonsteroid anti-inflammatory drug, after single and multiple Oral administration
SCOTT, Graham, OSBORNE, Stuart A, GREIG, Gerard, HARTMANN, Stefan, EBELIN, Marie-Eve, BURTIN, Pascale, RAPPERSBERGER, Klemens, KOMAR, Michael, WOLFF, Klaus
Published in Clinical pharmacokinetics (01.01.2003)
Published in Clinical pharmacokinetics (01.01.2003)
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Test-Retest Reliability of Task-based and Resting-state Blood Oxygen Level Dependence and Cerebral Blood Flow measures
Holiga, Stefan, Sambataro, Fabio, Lucy, Cecile, Greig, Gerard, Sarkar, Neena, Renken, Remco J, Marsman, Jan-Bernard C, Schobel, Scott A, Bertolino, Alessandro, Dukart, Juergen
Published in bioRxiv (22.10.2018)
Published in bioRxiv (22.10.2018)
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