Evaluation of cytosine base editing and adenine base editing as a potential treatment for alpha-1 antitrypsin deficiency
Packer, Michael S., Chowdhary, Vivek, Lung, Genesis, Cheng, Lo-I, Aratyn-Schaus, Yvonne, Leboeuf, Dominique, Smith, Sarah, Shah, Aalok, Chen, Delai, Zieger, Marina, Cafferty, Brian J., Yan, Bo, Ciaramella, Giuseppe, Gregoire, Francine M., Mueller, Christian
Published in Molecular therapy (06.04.2022)
Published in Molecular therapy (06.04.2022)
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Gene Editing Technologies to Target HBV cccDNA
Martinez, Maria Guadalupe, Smekalova, Elena, Combe, Emmanuel, Gregoire, Francine, Zoulim, Fabien, Testoni, Barbara
Published in Viruses (28.11.2022)
Published in Viruses (28.11.2022)
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Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing
Zhang, Xinfu, Zhao, Weiyu, Nguyen, Giang N, Zhang, Chengxiang, Zeng, Chunxi, Yan, Jingyue, Du, Shi, Hou, Xucheng, Li, Wenqing, Jiang, Justin, Deng, Binbin, McComb, David W, Dorkin, Robert, Shah, Aalok, Barrera, Luis, Gregoire, Francine, Singh, Manmohan, Chen, Delai, Sabatino, Denise E, Dong, Yizhou
Published in Science advances (01.08.2020)
Published in Science advances (01.08.2020)
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Understanding Adipocyte Differentiation
GREGOIRE, FRANCINE M, SMAS, CYNTHIA M, SUL, HEI SOOK
Published in Physiological reviews (01.07.1998)
Published in Physiological reviews (01.07.1998)
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Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivo
Smekalova, Elena M., Martinez, Maria G., Combe, Emmanuel, Kumar, Anuj, Dejene, Selam, Leboeuf, Dominique, Chen, Chao-Ying, Dorkin, J. Robert, Shuang, Lan Shuan, Kieft, Sarah, Young, Lauren, Barrera, Luis Alberto, Packer, Michael S., Ciaramella, Giuseppe, Testoni, Barbara, Gregoire, Francine, Zoulim, Fabien
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Published in Molecular therapy. Nucleic acids (12.03.2024)
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Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?
Shui, Guanghou, Stebbins, Jeffrey William, Lam, Buu Duyen, Cheong, Wei Fun, Lam, Sin Man, Gregoire, Francine, Kusonoki, Jun, Wenk, Markus R
Published in PloS one (04.05.2011)
Published in PloS one (04.05.2011)
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MBX-102/JNJ39659100, a Novel Peroxisome Proliferator-Activated Receptor-Ligand with Weak Transactivation Activity Retains Antidiabetic Properties in the Absence of Weight Gain and Edema
Gregoire, Francine M, Zhang, Fang, Clarke, Holly J, Gustafson, Thomas A, Sears, Dorothy D, Favelyukis, Svetlana, Lenhard, James, Rentzeperis, Dennis, Clemens, L. Edward, Mu, Yi, Lavan, Brian E
Published in Molecular endocrinology (Baltimore, Md.) (01.07.2009)
Published in Molecular endocrinology (Baltimore, Md.) (01.07.2009)
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Left ventricular diastolic dysfunction in nonhuman primate model of dysmetabolism and diabetes
Gu, Haihua, Liu, Yongqiang, Mei, Shuang, Wang, Bingdi, Sun, Guofeng, Wang, Xiaoli, Xiao, Yongfu, Staup, Michael, Gregoire, Francine M, Chng, Keefe, Wang, Yixin Jim
Published in BMC cardiovascular disorders (30.10.2015)
Published in BMC cardiovascular disorders (30.10.2015)
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Halofenate Is a Selective Peroxisome Proliferator–Activated Receptor γ Modulator With Antidiabetic Activity
ALIEN, Tamara, FANG ZHANG, MOODIE, Shonna A, CLEMENS, L. Edward, SMITH, Aaron, GREGOIRE, Francine, BELL, Andrea, MUSCAT, George E. O, GUSTAFSON, Thomas A
Published in Diabetes (New York, N.Y.) (01.09.2006)
Published in Diabetes (New York, N.Y.) (01.09.2006)
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Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys
Wang, Xiaoli, Hansen, Barbara C, Shi, Da, Fang, Yupeng, Du, Fenglai, Wang, Bingdi, Chen, Yaxiong Michael, Gregoire, Francine M, Wang, Yi-Xin Jim
Published in Diabetology and metabolic syndrome (25.07.2013)
Published in Diabetology and metabolic syndrome (25.07.2013)
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Diet-induced obesity and hepatic gene expression alterations in C57BL/6J and ICAM-1-deficient mice
Gregoire, Francine M, Zhang, Qin, Smith, Steven J, Tong, Carmen, Ross, David, Lopez, Henry, West, David B
Published in American journal of physiology: endocrinology and metabolism (01.03.2002)
Published in American journal of physiology: endocrinology and metabolism (01.03.2002)
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Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets. A common mechanism for glucose toxicity and lipotoxicity?
Zhou, Yun-Ping, Marlen, Kimberly, Palma, John F, Schweitzer, Anthony, Reilly, Linda, Gregoire, Francine M, Xu, Gann G, Blume, John E, Johnson, Jeffrey D
Published in The Journal of biological chemistry (19.12.2003)
Published in The Journal of biological chemistry (19.12.2003)
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MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR-γ Agonist Lowers Triglyceride Independently of PPAR-α Activation
Chandalia, Apurva, Clarke, Holly J., Clemens, L. Edward, Pandey, Bindu, Vicena, Vic, Lee, Paul, Lavan, Brian E., Gregoire, Francine M.
Published in PPAR Research (01.01.2009)
Published in PPAR Research (01.01.2009)
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MBX-102/JNJ39659100, a Novel Peroxisome Proliferator Activated Receptor-γ Ligand with Weak Transactivation Activity Retains Full Anti-Diabetic Properties in the Absence of Side Effects
Gregoire, Francine M, Zhang, Fang, Clarke, Holly J, Gustafson, Thomas A, Sears, Dorothy D, Favelyukis, Svetlana, Lenhard, James, Rentzeperis, Dennis, Clemens, L. Edward, Mu, Yi, Lavan, Brian E
Published in The journal of clinical endocrinology and metabolism (01.06.2009)
Published in The journal of clinical endocrinology and metabolism (01.06.2009)
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Journal Article
MBX-102/JNJ39659100, a Novel Peroxisome Proliferator Activated Receptor-γ Ligand with Weak Transactivation Activity Retains Full Anti-Diabetic Properties in the Absence of Side Effects
Gregoire, Francine M, Zhang, Fang, Clarke, Holly J, Gustafson, Thomas A, Sears, Dorothy D, Favelyukis, Svetlana, Lenhard, James, Rentzeperis, Dennis, Clemens, L. Edward, Mu, Yi, Lavan, Brian E
Published in Endocrine reviews (01.06.2009)
Published in Endocrine reviews (01.06.2009)
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T3 stimulates resting metabolism and UCP-2 and UCP-3 mRNA but not nonphosphorylating mitochondrial respiration in mice
Jekabsons, Mika B, Gregoire, Francine M, Schonfeld-Warden, Nancy A, Warden, Craig H, Horwitz, B. A
Published in American journal of physiology: endocrinology and metabolism (01.08.1999)
Published in American journal of physiology: endocrinology and metabolism (01.08.1999)
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Effects of Metformin and Vanadium on Leptin Secretion from Cultured Rat Adipocytes
Mueller, Wendy M., Stanhope, Kimber L., Gregoire, Francine, Evans, Joseph L., Havel, Peter J.
Published in Obesity (Silver Spring, Md.) (01.10.2000)
Published in Obesity (Silver Spring, Md.) (01.10.2000)
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