Identification of HSP90 inhibitors as a novel class of senolytics
Fuhrmann-Stroissnigg, Heike, Ling, Yuan Yuan, Zhao, Jing, McGowan, Sara J., Zhu, Yi, Brooks, Robert W., Grassi, Diego, Gregg, Siobhan Q., Stripay, Jennifer L., Dorronsoro, Akaitz, Corbo, Lana, Tang, Priscilla, Bukata, Christina, Ring, Nadja, Giacca, Mauro, Li, Xuesen, Tchkonia, Tamara, Kirkland, James L., Niedernhofer, Laura J., Robbins, Paul D.
Published in Nature communications (04.09.2017)
Published in Nature communications (04.09.2017)
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Journal Article
NF-κB inhibition delays DNA damage-induced senescence and aging in mice
Tilstra, Jeremy S, Robinson, Andria R, Wang, Jin, Gregg, Siobhán Q, Clauson, Cheryl L, Reay, Daniel P, Nasto, Luigi A, St Croix, Claudette M, Usas, Arvydas, Vo, Nam, Huard, Johnny, Clemens, Paula R, Stolz, Donna B, Guttridge, Denis C, Watkins, Simon C, Garinis, George A, Wang, Yinsheng, Niedernhofer, Laura J, Robbins, Paul D
Published in The Journal of clinical investigation (01.07.2012)
Published in The Journal of clinical investigation (01.07.2012)
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Journal Article
Physiological consequences of defects in ERCC1–XPF DNA repair endonuclease
Gregg, Siobhán Q., Robinson, Andria Rasile, Niedernhofer, Laura J.
Published in DNA repair (15.07.2011)
Published in DNA repair (15.07.2011)
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Journal Article
Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction
Thongthip, Supawat, Bellani, Marina, Gregg, Siobhan Q, Sridhar, Sunandini, Conti, Brooke A, Chen, Yanglu, Seidman, Michael M, Smogorzewska, Agata
Published in Genes & development (15.03.2016)
Published in Genes & development (15.03.2016)
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Journal Article
Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders
Choi, Siwon, Wang, Wei, Ribeiro, Alexandrew J.S., Kalinowski, Agnieszka, Gregg, Siobhan Q., Opresko, Patricia L., Niedernhofer, Laura J., Rohde, Gustavo K., Dahl, Kris Noel
Published in Nucleus (Austin, Tex.) (01.11.2011)
Published in Nucleus (Austin, Tex.) (01.11.2011)
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Journal Article
A mouse model of accelerated liver aging caused by a defect in DNA repair
Gregg, Siobhán Q., Gutiérrez, Verónica, Rasile Robinson, Andria, Woodell, Tyler, Nakao, Atsunori, Ross, Mark A., Michalopoulos, George K., Rigatti, Lora, Rothermel, Carrie E., Kamileri, Irene, Garinis, George A., Beer Stolz, Donna, Niedernhofer, Laura J.
Published in Hepatology (Baltimore, Md.) (01.02.2012)
Published in Hepatology (Baltimore, Md.) (01.02.2012)
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Journal Article
A comprehensive approach to identification of pathogenic FANCA variants in Fanconi anemia patients and their families
Kimble, Danielle C., Lach, Francis P., Gregg, Siobhan Q., Donovan, Frank X., Flynn, Elizabeth K., Kamat, Aparna, Young, Alice, Vemulapalli, Meghana, Thomas, James W., Mullikin, James C., Auerbach, Arleen D., Smogorzewska, Agata, Chandrasekharappa, Settara C.
Published in Human mutation (01.02.2018)
Published in Human mutation (01.02.2018)
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Journal Article
Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice
Zarakowska, Ewelina, Czerwinska, Jolanta, Tupalska, Agnieszka, Yousefzadeh, Matt J, Gregg, Siobhán Q, Croix, Claudette M St, Niedernhofer, Laura J, Foksinski, Marek, Gackowski, Daniel, Szpila, Anna, Starczak, Marta, Tudek, Barbara, Olinski, Ryszard
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09.07.2018)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09.07.2018)
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Journal Article
ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation
Czerwińska, Jolanta, Nowak, Małgorzata, Wojtczak, Patrycja, Dziuban-Lech, Dorota, Cieśla, Jarosław M., Kołata, Daria, Gajewska, Beata, Barańczyk-Kuźma, Anna, Robinson, Andria R., Shane, Hillary L., Gregg, Siobhán Q., Rigatti, Lora H., Yousefzadeh, Matthew J., Gurkar, Aditi U., McGowan, Sara J., Kosicki, Konrad, Bednarek, Małgorzata, Zarakowska, Ewelina, Gackowski, Daniel, Oliński, Ryszard, Speina, Elżbieta, Niedernhofer, Laura J., Tudek, Barbara
Published in Free radical biology & medicine (20.08.2018)
Published in Free radical biology & medicine (20.08.2018)
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Journal Article
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging
Robinson, Andria R., Yousefzadeh, Matthew J., Rozgaja, Tania A., Wang, Jin, Li, Xuesen, Tilstra, Jeremy S., Feldman, Chelsea H., Gregg, Siobhán Q., Johnson, Caroline H., Skoda, Erin M., Frantz, Marie-Céline, Bell-Temin, Harris, Pope-Varsalona, Hannah, Gurkar, Aditi U., Nasto, Luigi A., Robinson, Renã A.S., Fuhrmann-Stroissnigg, Heike, Czerwinska, Jolanta, McGowan, Sara J., Cantu-Medellin, Nadiezhda, Harris, Jamie B., Maniar, Salony, Ross, Mark A., Trussoni, Christy E., LaRusso, Nicholas F., Cifuentes-Pagano, Eugenia, Pagano, Patrick J., Tudek, Barbara, Vo, Nam V., Rigatti, Lora H., Opresko, Patricia L., Stolz, Donna B., Watkins, Simon C., Burd, Christin E., Croix, Claudette M. St, Siuzdak, Gary, Yates, Nathan A., Robbins, Paul D., Wang, Yinsheng, Wipf, Peter, Kelley, Eric E., Niedernhofer, Laura J.
Published in Redox biology (01.07.2018)
Published in Redox biology (01.07.2018)
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Journal Article
A mouse model of accelerated liver aging due to a defect in DNA repair
Gregg, Siobhán Q., Gutiérrez, Verónica, Robinson, Andria Rasile, Woodell, Tyler, Nakao, Atsunori, Ross, Mark A., Michalopoulos, George K., Rigatti, Lora, Rothermel, Carrie E., Kamileri, Irene, Garinis, George, Stolz, Donna Beer, Niedernhofer, Laura J.
Published in Hepatology (Baltimore, Md.) (01.02.2012)
Published in Hepatology (Baltimore, Md.) (01.02.2012)
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Journal Article
NF-[kappa]B inhibition delays DNA damage-induced senescence and aging in mice
Tilstra, Jeremy S, Robinson, Andria R, Wang, Jin, Gregg, Siobhán Q, Clauson, Cheryl L, Reay, Daniel P, Nasto, Luigi A, St Croix, Claudette M, Usas, Arvydas, Vo, Nam, Huard, Johnny, Clemens, Paula R, Stolz, Donna B, Guttridge, Denis C, Watkins, Simon C, Garinis, George A, Wang, Yinsheng, Niedemhofer, Laura J, Robbins, Paul D
Published in The Journal of clinical investigation (01.07.2012)
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Published in The Journal of clinical investigation (01.07.2012)
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