LRRK2 activation in idiopathic Parkinson's disease
Di Maio, Roberto, Hoffman, Eric K, Rocha, Emily M, Keeney, Matthew T, Sanders, Laurie H, De Miranda, Briana R, Zharikov, Alevtina, Van Laar, Amber, Stepan, Antonia F, Lanz, Thomas A, Kofler, Julia K, Burton, Edward A, Alessi, Dario R, Hastings, Teresa G, Greenamyre, J Timothy
Published in Science translational medicine (25.07.2018)
Published in Science translational medicine (25.07.2018)
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Oxidative damage to macromolecules in human Parkinson disease and the rotenone model
Sanders, Laurie H., Timothy Greenamyre, J.
Published in Free radical biology & medicine (01.09.2013)
Published in Free radical biology & medicine (01.09.2013)
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Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease
De Miranda, Briana R., Rocha, Emily M., Bai, Qing, El Ayadi, Amina, Hinkle, David, Burton, Edward A., Timothy Greenamyre, J.
Published in Neurobiology of disease (01.07.2018)
Published in Neurobiology of disease (01.07.2018)
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PCR based determination of mitochondrial DNA copy number in multiple species
Rooney, John P, Ryde, Ian T, Sanders, Laurie H, Howlett, Evan H, Colton, Meryl D, Germ, Kaylyn E, Mayer, Greg D, Greenamyre, J Timothy, Meyer, Joel N
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
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Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
Espay, Alberto J, Vizcarra, Joaquin A, Marsili, Luca, Lang, Anthony E, Simon, David K, Merola, Aristide, Josephs, Keith A, Fasano, Alfonso, Morgante, Francesca, Savica, Rodolfo, Greenamyre, J Timothy, Cambi, Franca, Yamasaki, Tritia R, Tanner, Caroline M, Gan-Or, Ziv, Litvan, Irene, Mata, Ignacio F, Zabetian, Cyrus P, Brundin, Patrik, Fernandez, Hubert H, Standaert, David G, Kauffman, Marcelo A, Schwarzschild, Michael A, Sardi, S Pablo, Sherer, Todd, Perry, George, Leverenz, James B
Published in Neurology (12.02.2019)
Published in Neurology (12.02.2019)
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The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
Hallacli, Erinc, Kayatekin, Can, Nazeen, Sumaiya, Wang, Xiou H., Sheinkopf, Zoe, Sathyakumar, Shubhangi, Sarkar, Souvarish, Jiang, Xin, Dong, Xianjun, Di Maio, Roberto, Wang, Wen, Keeney, Matthew T., Felsky, Daniel, Sandoe, Jackson, Vahdatshoar, Aazam, Udeshi, Namrata D., Mani, D.R., Carr, Steven A., Lindquist, Susan, De Jager, Philip L., Bartel, David P., Myers, Chad L., Greenamyre, J. Timothy, Feany, Mel B., Sunyaev, Shamil R., Chung, Chee Yeun, Khurana, Vikram
Published in Cell (09.06.2022)
Published in Cell (09.06.2022)
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A highly reproducible rotenone model of Parkinson's disease
Cannon, Jason R, Tapias, Victor, Na, Hye Mee, Honick, Anthony S, Drolet, Robert E, Greenamyre, J. Timothy
Published in Neurobiology of disease (01.05.2009)
Published in Neurobiology of disease (01.05.2009)
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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease
Rocha, Emily M., De Miranda, Briana R., Castro, Sandra, Drolet, Robert, Hatcher, Nathan G., Yao, Lihang, Smith, Sean M., Keeney, Matthew T., Di Maio, Roberto, Kofler, Julia, Hastings, Teresa G., Greenamyre, J. Timothy
Published in Neurobiology of disease (01.02.2020)
Published in Neurobiology of disease (01.02.2020)
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Mitochondrial Iron Metabolism and Its Role in Neurodegeneration
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The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease
De Miranda, Briana R., Castro, Sandra L., Rocha, Emily M., Bodle, Christopher R., Johnson, Katrina E., Greenamyre, J. Timothy
Published in Neurobiology of disease (01.06.2021)
Published in Neurobiology of disease (01.06.2021)
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LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
Sanders, Laurie H, Laganière, Josée, Cooper, Oliver, Mak, Sally K, Vu, B. Joseph, Huang, Y. Anne, Paschon, David E, Vangipuram, Malini, Sundararajan, Ramya, Urnov, Fyodor D, Langston, J. William, Gregory, Philip D, Zhang, H. Steve, Greenamyre, J. Timothy, Isacson, Ole, Schüle, Birgitt
Published in Neurobiology of disease (01.02.2014)
Published in Neurobiology of disease (01.02.2014)
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Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology
Drolet, Robert E, Cannon, Jason R, Montero, Laura, Greenamyre, J. Timothy
Published in Neurobiology of disease (01.10.2009)
Published in Neurobiology of disease (01.10.2009)
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NADPH oxidase 2 activity in Parkinson's disease
Keeney, Matthew T., Hoffman, Eric K., Farmer, Kyle, Bodle, Christopher R., Fazzari, Marco, Zharikov, Alevtina, Castro, Sandra L., Hu, Xiaoping, Mortimer, Amanda, Kofler, Julia K., Cifuentes-Pagano, Eugenia, Pagano, Patrick J., Burton, Edward A., Hastings, Teresa G., Greenamyre, J. Timothy, Di Maio, Roberto
Published in Neurobiology of disease (01.08.2022)
Published in Neurobiology of disease (01.08.2022)
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