The future of stem cell therapies for Parkinson disease
Parmar, Malin, Grealish, Shane, Henchcliffe, Claire
Published in Nature reviews. Neuroscience (01.02.2020)
Published in Nature reviews. Neuroscience (01.02.2020)
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Journal Article
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease
Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Published in Cell stem cell (06.11.2014)
Published in Cell stem cell (06.11.2014)
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Journal Article
Generation of induced neurons via direct conversion in vivo
Torper, Olof, Pfisterer, Ulrich, Wolf, Daniel A., Pereira, Maria, Lau, Shong, Jakobsson, Johan, Björklund, Anders, Grealish, Shane, Parmar, Malin
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
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Journal Article
In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry
Torper, Olof, Ottosson, Daniella Rylander, Pereira, Maria, Lau, Shong, Cardoso, Tiago, Grealish, Shane, Parmar, Malin
Published in Cell reports (Cambridge) (21.07.2015)
Published in Cell reports (Cambridge) (21.07.2015)
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Journal Article
Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions
Kirkeby, Agnete, Grealish, Shane, Wolf, Daniel A., Nelander, Jenny, Wood, James, Lundblad, Martin, Lindvall, Olle, Parmar, Malin
Published in Cell reports (Cambridge) (28.06.2012)
Published in Cell reports (Cambridge) (28.06.2012)
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Journal Article
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Ottosson, Daniella Rylander, Lelos, Mariah J., Rifes, Pedro, Dunnett, Stephen B., Grealish, Shane, Perlmann, Thomas, Parmar, Malin
Published in Cell stem cell (05.01.2017)
Published in Cell stem cell (05.01.2017)
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Journal Article
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli
Tornero, Daniel, Tsupykov, Oleg, Granmo, Marcus, Rodriguez, Cristina, Grønning-Hansen, Marita, Thelin, Jonas, Smozhanik, Ekaterina, Laterza, Cecilia, Wattananit, Somsak, Ge, Ruimin, Tatarishvili, Jemal, Grealish, Shane, Brüstle, Oliver, Skibo, Galina, Parmar, Malin, Schouenborg, Jens, Lindvall, Olle, Kokaia, Zaal
Published in Brain (London, England : 1878) (01.03.2017)
Published in Brain (London, England : 1878) (01.03.2017)
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Journal Article
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease
Adler, Andrew F., Cardoso, Tiago, Nolbrant, Sara, Mattsson, Bengt, Hoban, Deirdre B., Jarl, Ulla, Wahlestedt, Jenny Nelander, Grealish, Shane, Björklund, Anders, Parmar, Malin
Published in Cell reports (Cambridge) (24.09.2019)
Published in Cell reports (Cambridge) (24.09.2019)
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Journal Article
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Published in Journal of comparative neurology (1911) (01.09.2018)
Published in Journal of comparative neurology (1911) (01.09.2018)
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Journal Article
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain
Thompson, Lachlan H., Grealish, Shane, Kirik, Deniz, Björklund, Anders
Published in The European journal of neuroscience (01.08.2009)
Published in The European journal of neuroscience (01.08.2009)
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Journal Article
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease
Grealish, Shane, Jönsson, Marie E., Li, Meng, Kirik, Deniz, Björklund, Anders, Thompson, Lachlan H.
Published in Brain (London, England : 1878) (01.02.2010)
Published in Brain (London, England : 1878) (01.02.2010)
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Journal Article
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
Grealish, Shane, Heuer, Andreas, Cardoso, Tiago, Kirkeby, Agnete, Jönsson, Marie, Johansson, Jenny, Björklund, Anders, Jakobsson, Johan, Parmar, Malin
Published in Stem cell reports (09.06.2015)
Published in Stem cell reports (09.06.2015)
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Journal Article
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells
Lehnen, Daniela, Barral, Serena, Cardoso, Tiago, Grealish, Shane, Heuer, Andreas, Smiyakin, Andrej, Kirkeby, Agnete, Kollet, Jutta, Cremer, Harold, Parmar, Malin, Bosio, Andreas, Knöbel, Sebastian
Published in Current stem cell reports (10.10.2017)
Published in Current stem cell reports (10.10.2017)
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Journal Article
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism
Rylander, Daniella, Bagetta, Vincenza, Pendolino, Valentina, Zianni, Elisa, Grealish, Shane, Gardoni, Fabrizio, Di Luca, Monica, Calabresi, Paolo, Cenci, M Angela, Picconi, Barbara
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
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Journal Article
Lineage reprogramming: A shortcut to generating functional neurons from fibroblasts
Grealish, Shane, Jakobsson, Johan, Parmar, Malin
Published in Cell cycle (Georgetown, Tex.) (15.10.2011)
Published in Cell cycle (Georgetown, Tex.) (15.10.2011)
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Journal Article
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease
Grealish, Shane, Mattsson, Bengt, Draxler, Peter, Björklund, Anders
Published in The European journal of neuroscience (01.06.2010)
Published in The European journal of neuroscience (01.06.2010)
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Journal Article
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain
Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Published in Scientific reports (11.09.2014)
Published in Scientific reports (11.09.2014)
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Journal Article
GDNF is not required for catecholaminergic neuron survival in vivo
Kopra, Jaakko, Vilenius, Carolina, Grealish, Shane, Härma, Mari-Anne, Varendi, Kärt, Lindholm, Jesse, Castrén, Eero, Võikar, Vootele, Björklund, Anders, Piepponen, T Petteri, Saarma, Mart, Andressoo, Jaan-Olle
Published in Nature neuroscience (01.03.2015)
Published in Nature neuroscience (01.03.2015)
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