The ins and outs of selective kinase inhibitor development
Müller, Susanne, Chaikuad, Apirat, Gray, Nathanael S, Knapp, Stefan
Published in Nature chemical biology (01.11.2015)
Published in Nature chemical biology (01.11.2015)
Get full text
Journal Article
Targeting cancer with small molecule kinase inhibitors
Gray, Nathanael S, Zhang, Jianming, Yang, Priscilla L
Published in Nature reviews. Cancer (01.01.2009)
Published in Nature reviews. Cancer (01.01.2009)
Get full text
Journal Article
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
Dutt, Amit, Ramos, Alex H, Hammerman, Peter S, Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S, Meyerson, Matthew
Published in PloS one (07.06.2011)
Published in PloS one (07.06.2011)
Get full text
Journal Article
Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Published in Cell stem cell (02.10.2014)
Published in Cell stem cell (02.10.2014)
Get full text
Journal Article
Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation
Zhang, Tinghu, Hatcher, John M, Teng, Mingxing, Gray, Nathanael S, Kostic, Milka
Published in Cell chemical biology (21.11.2019)
Published in Cell chemical biology (21.11.2019)
Get full text
Journal Article
YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers
Galli, Giorgio G., Carrara, Matteo, Yuan, Wei-Chien, Valdes-Quezada, Christian, Gurung, Basanta, Pepe-Mooney, Brian, Zhang, Tinghu, Geeven, Geert, Gray, Nathanael S., de Laat, Wouter, Calogero, Raffaele A., Camargo, Fernando D.
Published in Molecular cell (15.10.2015)
Published in Molecular cell (15.10.2015)
Get full text
Journal Article
Plasticity in binding confers selectivity in ligand-induced protein degradation
Nowak, Radosław P., DeAngelo, Stephen L., Buckley, Dennis, He, Zhixiang, Donovan, Katherine A., An, Jian, Safaee, Nozhat, Jedrychowski, Mark P., Ponthier, Charles M., Ishoey, Mette, Zhang, Tinghu, Mancias, Joseph D., Gray, Nathanael S., Bradner, James E., Fischer, Eric S.
Published in Nature chemical biology (01.07.2018)
Published in Nature chemical biology (01.07.2018)
Get full text
Journal Article
EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
Ercan, Dalia, Choi, Hwan Geun, Yun, Cai-Hong, Capelletti, Marzia, Xie, Ting, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A
Published in Clinical cancer research (01.09.2015)
Published in Clinical cancer research (01.09.2015)
Get full text
Journal Article
CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Young, Richard A., Gray, Nathanael S., Zhao, Jean J.
Published in Cell (24.09.2015)
Published in Cell (24.09.2015)
Get full text
Journal Article
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Weintraub, Abraham S., Li, Charles H., Zamudio, Alicia V., Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Jaenisch, Rudolf, Bradner, James E., Gray, Nathanael S., Young, Richard A.
Published in Cell (14.12.2017)
Published in Cell (14.12.2017)
Get full text
Journal Article
Exploration of Type II Binding Mode: A Privileged Approach for Kinase Inhibitor Focused Drug Discovery?
Zhao, Zheng, Wu, Hong, Wang, Li, Liu, Yi, Knapp, Stefan, Liu, Qingsong, Gray, Nathanael S
Published in ACS chemical biology (20.06.2014)
Published in ACS chemical biology (20.06.2014)
Get full text
Journal Article
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
Faust, Tyler B., Yoon, Hojong, Nowak, Radosław P., Donovan, Katherine A., Li, Zhengnian, Cai, Quan, Eleuteri, Nicholas A., Zhang, Tinghu, Gray, Nathanael S., Fischer, Eric S.
Published in Nature chemical biology (01.01.2020)
Published in Nature chemical biology (01.01.2020)
Get full text
Journal Article
Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
Zhou, Wen, Whiteley, Aaron T., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Nowak, Radosław P., Fischer, Eric S., Gray, Nathanael S., Mekalanos, John J., Kranzusch, Philip J.
Published in Cell (12.07.2018)
Published in Cell (12.07.2018)
Get full text
Journal Article
Partitioning of cancer therapeutics in nuclear condensates
Klein, Isaac A, Boija, Ann, Afeyan, Lena K, Hawken, Susana Wilson, Fan, Mengyang, Dall'Agnese, Alessandra, Oksuz, Ozgur, Henninger, Jonathan E, Shrinivas, Krishna, Sabari, Benjamin R, Sagi, Ido, Clark, Victoria E, Platt, Jesse M, Kar, Mrityunjoy, McCall, Patrick M, Zamudio, Alicia V, Manteiga, John C, Coffey, Eliot L, Li, Charles H, Hannett, Nancy M, Guo, Yang Eric, Decker, Tim-Michael, Lee, Tong Ihn, Zhang, Tinghu, Weng, Jing-Ke, Taatjes, Dylan J, Chakraborty, Arup, Sharp, Phillip A, Chang, Young Tae, Hyman, Anthony A, Gray, Nathanael S, Young, Richard A
Published in Science (American Association for the Advancement of Science) (19.06.2020)
Published in Science (American Association for the Advancement of Science) (19.06.2020)
Get full text
Journal Article
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
Olson, Calla M, Jiang, Baishan, Erb, Michael A, Liang, Yanke, Doctor, Zainab M, Zhang, Zinan, Zhang, Tinghu, Kwiatkowski, Nicholas, Boukhali, Myriam, Green, Jennifer L, Haas, Wilhelm, Nomanbhoy, Tyzoon, Fischer, Eric S, Young, Richard A, Bradner, James E, Winter, Georg E, Gray, Nathanael S
Published in Nature chemical biology (01.02.2018)
Published in Nature chemical biology (01.02.2018)
Get full text
Journal Article