Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages
Rosenbluth, Jennifer M., Schackmann, Ron C. J., Gray, G. Kenneth, Selfors, Laura M., Li, Carman Man-Chung, Boedicker, Mackenzie, Kuiken, Hendrik J., Richardson, Andrea, Brock, Jane, Garber, Judy, Dillon, Deborah, Sachs, Norman, Clevers, Hans, Brugge, Joan S.
Published in Nature communications (06.04.2020)
Published in Nature communications (06.04.2020)
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Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
Li, Carman Man-Chung, Shapiro, Hana, Tsiobikas, Christina, Selfors, Laura M., Chen, Huidong, Rosenbluth, Jennifer, Moore, Kaitlin, Gupta, Kushali P., Gray, G. Kenneth, Oren, Yaara, Steinbaugh, Michael J., Guerriero, Jennifer L., Pinello, Luca, Regev, Aviv, Brugge, Joan S.
Published in Cell reports (Cambridge) (29.12.2020)
Published in Cell reports (Cambridge) (29.12.2020)
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A human breast atlas integrating single-cell proteomics and transcriptomics
Gray, G. Kenneth, Li, Carman Man-Chung, Rosenbluth, Jennifer M., Selfors, Laura M., Girnius, Nomeda, Lin, Jia-Ren, Schackmann, Ron C.J., Goh, Walter L., Moore, Kaitlin, Shapiro, Hana K., Mei, Shaolin, D’Andrea, Kurt, Nathanson, Katherine L., Sorger, Peter K., Santagata, Sandro, Regev, Aviv, Garber, Judy E., Dillon, Deborah A., Brugge, Joan S.
Published in Developmental cell (06.06.2022)
Published in Developmental cell (06.06.2022)
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Single-cell and spatial analyses reveal a tradeoff between murine mammary proliferation and lineage programs associated with endocrine cues
Gray, G. Kenneth, Girnius, Nomeda, Kuiken, Hendrik J., Henstridge, Aylin Z., Brugge, Joan S.
Published in Cell reports (Cambridge) (31.10.2023)
Published in Cell reports (Cambridge) (31.10.2023)
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NF-κB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma
McFarland, Braden C, Hong, Suk W, Rajbhandari, Rajani, Twitty, Jr, George B, Gray, G Kenneth, Yu, Hao, Benveniste, Etty N, Nozell, Susan E
Published in PloS one (11.11.2013)
Published in PloS one (11.11.2013)
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A transcriptional response to replication stress selectively expands a subset of Brca2-mutant mammary epithelial cells
Najafabadi, Maryam Ghaderi, Gray, G. Kenneth, Kong, Li Ren, Gupta, Komal, Perera, David, Naylor, Huw, Brugge, Joan S., Venkitaraman, Ashok R., Shehata, Mona
Published in Nature communications (25.08.2023)
Published in Nature communications (25.08.2023)
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Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts
Kuiken, Hendrik J., Dhakal, Sabin, Selfors, Laura M., Friend, Chandler M., Zhang, Tian, Callari, Maurizio, Schackmann, Ron C. J., Gray, G. Kenneth, Crowdis, Jett, Bhang, Hyo-eun C., Baslan, Timour, Stegmeier, Frank, Gygi, Steven P., Caldas, Carlos, Brugge, Joan S.
Published in Oncogene (03.01.2022)
Published in Oncogene (03.01.2022)
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Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids
Meng, Qingda, Xie, Shanshan, Gray, G Kenneth, Dezfulian, Mohammad H, Li, Weilin, Huang, Ling, Akshinthala, Dipikaa, Ferrer, Elizabeth, Conahan, Catherine, Perea Del Pino, Sofia, Grossman, Joseph, Elledge, Stephen J, Hidalgo, Manuel, Muthuswamy, Senthil K
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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MicroRNA‐31 is required for astrocyte specification
Meares, Gordon P., Rajbhandari, Rajani, Gerigk, Magda, Tien, Chih‐Liang, Chang, Chenbei, Fehling, Samuel C., Rowse, Amber, Mulhern, Kayln C., Nair, Sindhu, Gray, G. Kenneth, Berbari, Nicolas F., Bredel, Markus, Benveniste, Etty N., Nozell, Susan E.
Published in Glia (01.05.2018)
Published in Glia (01.05.2018)
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Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma
Rajbhandari, Rajani, McFarland, Braden C, Patel, Ashish, Gerigk, Magda, Gray, G Kenneth, Fehling, Samuel C, Bredel, Markus, Berbari, Nicolas F, Kim, Hyunsoo, Marks, Margaret P, Meares, Gordon P, Sinha, Tanvi, Chuang, Jeffrey, Benveniste, Etty N, Nozell, Susan E
Published in Oncotarget (10.07.2015)
Published in Oncotarget (10.07.2015)
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PI3Kβ controls immune evasion in PTEN-deficient breast tumours
Bergholz, Johann S., Wang, Qiwei, Wang, Qi, Ramseier, Michelle, Prakadan, Sanjay, Wang, Weihua, Fang, Rong, Kabraji, Sheheryar, Zhou, Qian, Gray, G. Kenneth, Abell-Hart, Kayley, Xie, Shaozhen, Guo, Xiaocan, Gu, Hao, Von, Thanh, Jiang, Tao, Tang, Shuang, Freeman, Gordon J., Kim, Hye-Jung, Shalek, Alex K., Roberts, Thomas M., Zhao, Jean J.
Published in Nature (London) (04.05.2023)
Published in Nature (London) (04.05.2023)
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NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age
Gray, G Kenneth, McFarland, Braden C, Nozell, Susan E, Benveniste, Etty N
Published in Expert review of neurotherapeutics (01.11.2014)
Published in Expert review of neurotherapeutics (01.11.2014)
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Activation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells
McFarland, Braden C, Gray, G Kenneth, Nozell, Susan E, Hong, Suk W, Benveniste, Etty N
Published in Molecular cancer research (01.05.2013)
Published in Molecular cancer research (01.05.2013)
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Glutathione supports lipid abundance in vivo
Asantewaa, Gloria, Tuttle, Emily T, Ward, Nathan P, Kang, Yun Pyo, Kim, Yumi, Kavanagh, Madeline E, Girnius, Nomeda, Chen, Ying, Duncan, Renae, Rodriguez, Katherine, Hecht, Fabio, Zocchi, Marco, Smorodintsev-Schiller, Leonid, Scales, TashJaé Q, Taylor, Kira, Alimohammadi, Fatemeh, Sechrist, Zachary R, Agostini-Vulaj, Diana, Schafer, Xenia L, Chang, Hayley, Smith, Zachary, O'Connor, Thomas N, Whelan, Sarah, Selfors, Laura M, Crowdis, Jett, Gray, G Kenneth, Bronson, Roderick T, Brenner, Dirk, Rufini, Alessandro, Dirksen, Robert T, Hezel, Aram F, Huber, Aaron R, Munger, Josh, Cravatt, Benjamin F, Vasiliou, Vasilis, Cole, Calvin L, DeNicola, Gina M, Harris, Isaac S
Published in bioRxiv (11.02.2023)
Published in bioRxiv (11.02.2023)
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PI3Kβ controls immune evasion in PTENdeficient breast tumours
Bergholz, Johann S, Wang, Qiwei, Wang, Qi, Ramseier, Michelle, Prakadan, Sanjay, Wang, Weihua, Fang, Rong, Kabraji, Sheheryar, Zhou, Qian, Gray, G Kenneth, Abell-Hart, Kayley, Xie, Shaozhen, Guo, Xiaocan, Gu, Hao, Von, Thanh, Jiang, Tao, Tang, Shuang, Freeman, Gordon J, Kim, Hye-Jung, Shalek, Alex K, Roberts, Thomas M, Zhao, Jean J
Published in Nature (London) (04.05.2023)
Published in Nature (London) (04.05.2023)
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Abstract PD7-03: A living biobank of normal mammary organoids derived from patients at low and increased risk of developing breast cancer
Rosenbluth, Jennifer M, Li, Carman Man-Chung, Gray, Kenneth G, Gao, Walter, Schackmann, Ron CJ, Zoeller, Jason J, Selfors, Laura M, Moore, Kaitlin, Dillon, Deborah, Garber, Judy, Brugge, Joan S
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression
Asantewaa, Gloria, Tuttle, Emily T., Ward, Nathan P., Kang, Yun Pyo, Kim, Yumi, Kavanagh, Madeline E., Girnius, Nomeda, Chen, Ying, Rodriguez, Katherine, Hecht, Fabio, Zocchi, Marco, Smorodintsev-Schiller, Leonid, Scales, TashJaé Q., Taylor, Kira, Alimohammadi, Fatemeh, Duncan, Renae P., Sechrist, Zachary R., Agostini-Vulaj, Diana, Schafer, Xenia L., Chang, Hayley, Smith, Zachary R., O’Connor, Thomas N., Whelan, Sarah, Selfors, Laura M., Crowdis, Jett, Gray, G. Kenneth, Bronson, Roderick T., Brenner, Dirk, Rufini, Alessandro, Dirksen, Robert T., Hezel, Aram F., Huber, Aaron R., Munger, Joshua, Cravatt, Benjamin F., Vasiliou, Vasilis, Cole, Calvin L., DeNicola, Gina M., Harris, Isaac S.
Published in Nature communications (21.07.2024)
Published in Nature communications (21.07.2024)
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NF-[kappa]B-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma
McFarland, Braden C, Hong, Suk W, Rajbhandari, Rajani, Twitty, George B, Gray, G. Kenneth, Yu, Hao, Benveniste, Etty N, Nozell, Susan E
Published in PloS one (11.11.2013)
Published in PloS one (11.11.2013)
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LAB-CELL BIOLOGY AND SIGNALING
Kijima, N., Hosen, N., Kagawa, N., Hashimoto, N., Chiba, Y., Kinoshita, M., Sugiyama, H., Yoshimine, T., Kim, Y. Z., Kim, K. H., Lee, E. H., Hu, B., Sim, H., Mohan, N., Agudelo-Garcia, P., Nuovo, G., Cole, S., Viapiano, M. S., McFarland, B. C., Hong, S. W., Rajbhandari, R., Twitty, G. B., Kenneth Gray, G., Yu, H., Langford, C. P., Yancey Gillespie, G., Benveniste, E. N., Nozell, S. E., Nitta, R., Mitra, S., Bui, T., Li, G., Munoz, J. L., Rodriguez-Cruz, V., Rameshwar, P., See, W. L., Mukherjee, J., Shannon, K. M., Pieper, R. O., Floyd, D. H., Xiao, A., Purow, B. W., Lavon, I., Zrihan, D., Refael, M., Bier, A., Canello, T., Siegal, T., Granit, A., Xie, Q., Wang, X., Gong, Y., Mao, Y., Chen, X., Zhou, L., Lee, S. X., Tunkyi, A., Wong, E. T., Swanson, K. D., Zhang, K., Chen, L., Zhang, J., Shi, Z., Han, L., Pu, P., Kang, C., Cho, W. H., Ogawa, D., Godlewski, J., Bronisz, A., Antonio Chiocca, E., Mustafa, D. A. M., Sieuwerts, A. M., Smid, M., de Weerd, V., Martens, J. W., Foekens, J. A., Kros, J. M., McCulloch, C., Graff, J., Sui, Y., Dinn, S., Huang, Y., Li, Q., Fiona, G., Nakashima, H., Leiss, L., Manini, I., Enger, P. O., Yang, C., Iyer, R., Yu, A. C. H., Li, S., Ikejiri, B. L., Zhuang, Z., Lonser, R., Massoud, T. F., Paulmurugan, R., Gambhir, S. S., Merrill, M. J.
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2012)
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2012)
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