Antiviral and Anticancer Optimization Studies of the DNA-binding Marine Natural Product Aaptamine
Bowling, John J, Pennaka, Hari K, Ivey, Kelly, Wahyuono, Subagus, Kelly, Michelle, Schinazi, Raymond F, Valeriote, Frederick A, Graves, David E, Hamann, Mark T
Published in Chemical biology & drug design (01.03.2008)
Published in Chemical biology & drug design (01.03.2008)
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Amsacrine as a Topoisomerase II Poison: Importance of Drug–DNA Interactions
Ketron, Adam C, Denny, William A, Graves, David E, Osheroff, Neil
Published in Biochemistry (Easton) (28.02.2012)
Published in Biochemistry (Easton) (28.02.2012)
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Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance
Aldred, Katie J, McPherson, Sylvia A, Wang, Pengfei, Kerns, Robert J, Graves, David E, Turnbough, Charles L, Osheroff, Neil
Published in Biochemistry (Easton) (10.01.2012)
Published in Biochemistry (Easton) (10.01.2012)
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Journal Article
Influence of Substituent Modifications on DNA Binding Energetics of Acridine-Based Anticancer Agents
Hutchins, Rachel A, Crenshaw, James M, Graves, David E, Denny, William A
Published in Biochemistry (Easton) (25.11.2003)
Published in Biochemistry (Easton) (25.11.2003)
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Journal Article
Interactions between the Etoposide Derivative F14512 and Human Type II Topoisomerases: Implications for the C4 Spermine Moiety in Promoting Enzyme-Mediated DNA Cleavage
Gentry, Amanda C, Pitts, Steven L, Jablonsky, Michael J, Bailly, Christian, Graves, David E, Osheroff, Neil
Published in Biochemistry (Easton) (19.04.2011)
Published in Biochemistry (Easton) (19.04.2011)
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Telomeric G-quadruplex-forming DNA fragments induce TLR9-mediated and LL-37-regulated invasion in breast cancer cells in vitro
Tuomela, Johanna M., Sandholm, Jouko A., Kaakinen, Mika, Hayden, Katherine L., Haapasaari, Kirsi-Maria, Jukkola-Vuorinen, Arja, Kauppila, Joonas H., Lehenkari, Petri P., Harris, Kevin W., Graves, David E., Selander, Katri S.
Published in Breast cancer research and treatment (01.01.2016)
Published in Breast cancer research and treatment (01.01.2016)
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Journal Article
Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion
Kauppila, Joonas H., Karttunen, Tuomo J., Saarnio, Juha, Nyberg, Pia, Salo, Tuula, Graves, David E., Lehenkari, Petri P., Selander, Katri S.
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.06.2013)
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.06.2013)
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Substituents on Etoposide That Interact with Human Topoisomerase IIα in the Binary Enzyme−Drug Complex: Contributions to Etoposide Binding and Activity
Bender, Ryan P, Jablonksy, Michael J, Shadid, Mohammad, Romaine, Ian, Dunlap, Norma, Anklin, Clemens, Graves, David E, Osheroff, Neil
Published in Biochemistry (Easton) (15.04.2008)
Published in Biochemistry (Easton) (15.04.2008)
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Journal Article
Influence of the Amino Substituents in the Interaction of Ethidium Bromide with DNA
Garbett, Nichola C., Hammond, Nicholas B., Graves, David E.
Published in Biophysical journal (01.12.2004)
Published in Biophysical journal (01.12.2004)
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Journal Article
Contributions of the D-Ring to the Activity of Etoposide against Human Topoisomerase IIα: Potential Interactions with DNA in the Ternary Enzyme–Drug–DNA Complex
Pitts, Steven L, Jablonksy, Michael J, Duca, Maria, Dauzonne, Daniel, Monneret, Claude, Arimondo, Paola B, Anklin, Clemens, Graves, David E, Osheroff, Neil
Published in Biochemistry (Easton) (07.06.2011)
Published in Biochemistry (Easton) (07.06.2011)
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Journal Article
Topoisomerase II−Drug Interaction Domains: Identification of Substituents on Etoposide That Interact with the Enzyme
Wilstermann, Amy M, Bender, Ryan P, Godfrey, Murrell, Choi, Sungjo, Anklin, Clemens, Berkowitz, David B, Osheroff, Neil, Graves, David E
Published in Biochemistry (Easton) (17.07.2007)
Published in Biochemistry (Easton) (17.07.2007)
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Covalent Attachment of Ethidium to DNA Results in Enhanced Topoisomerase II-Mediated DNA Cleavage
Marx, Geoffrey, Zhou, Hui, Graves, David E, Osheroff, Neil
Published in Biochemistry (Easton) (16.12.1997)
Published in Biochemistry (Easton) (16.12.1997)
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