Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer
Ramanathan, Ramesh K., Von Hoff, Daniel D., Eskens, Ferry, Blumenschein, George, Richards, Donald, Genvresse, Isabelle, Reschke, Susanne, Granvil, Camille, Skubala, Adam, Peña, Carol, Mross, Klaus
Published in Targeted oncology (01.04.2020)
Published in Targeted oncology (01.04.2020)
Get full text
Journal Article
Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial
GUILHOT, François, HUGHES, Timothy P, CORTES, Jorge, DRUKER, Brian J, BACCARANI, Michele, GATHMANN, Insa, HAYES, Michael, GRANVIL, Camille, YANFENG WANG
Published in Haematologica (Roma) (01.05.2012)
Published in Haematologica (Roma) (01.05.2012)
Get full text
Journal Article
Correction to: Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer
Ramanathan, Ramesh K., Von Hoff, Daniel D., Eskens, Ferry, Blumenschein, George, Richards, Donald, Genvresse, Isabelle, Reschke, Susanne, Granvil, Camille, Skubala, Adam, Peña, Carol, Mross, Klaus
Published in Targeted oncology (01.12.2020)
Published in Targeted oncology (01.12.2020)
Get full text
Journal Article
Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography–tandem mass spectrometry
Arnold, Dana R., Granvil, Camille P., Ward, Keith W., Proksch, Joel W.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2008)
Get full text
Journal Article
Ocular pharmacokinetics of besifloxacin following topical administration to rabbits, monkeys, and humans
Proksch, Joel W, Granvil, Camille P, Siou-Mermet, Raphaële, Comstock, Timothy L, Paterno, Michael R, Ward, Keith W
Published in Journal of ocular pharmacology and therapeutics (01.08.2009)
Published in Journal of ocular pharmacology and therapeutics (01.08.2009)
Get more information
Journal Article
Expression of the Human CYP3A4 Gene in the Small Intestine of Transgenic Mice: In Vitro Metabolism and Pharmacokinetics of Midazolam
GRANVIL, Camille P, YU, Ai-Ming, ELIZONDO, Guillermo, AKIYAMA, Taro E, CHEUNG, Connie, FEIGENBAUM, Lionel, KRAUSZ, Kristopher W, GONZALEZ, Frank J
Published in Drug metabolism and disposition (01.05.2003)
Published in Drug metabolism and disposition (01.05.2003)
Get full text
Journal Article
4-Hydroxylation of Debrisoquine by Human CYP1A1 and Its Inhibition by Quinidine and Quinine
Granvil, Camille P, Krausz, Kristopher W, Gelboin, Harry V, Idle, Jeffrey R, Gonzalez, Frank J
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
Get full text
Journal Article
The Relative Contribution of Monoamine Oxidase and Cytochrome P450 Isozymes to the Metabolic Deamination of the Trace Amine Tryptamine
Yu, Ai-Ming, Granvil, Camille P, Haining, Robert L, Krausz, Kristopher W, Corchero, Javier, Küpfer, Adrian, Idle, Jeffrey R, Gonzalez, Frank J
Published in The Journal of pharmacology and experimental therapeutics (01.02.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2003)
Get full text
Journal Article
A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors
RODON, Jordi, TAWBI, Hussein A, LIN YANG, GRANVIL, Camille, EUNJU HURH, ROSE, Kristine L, AMAKYE, Dereck D, DUMMER, Reinhard, MITA, Alain C, THOMAS, Anne L, STOLLER, Ronald G, TURTSCHI, Christian P, BASELGA, Jose, SARANTOPOULOS, John, MAHALINGAM, Devalingam, YAPING SHOU, MOLES, Melissa A
Published in Clinical cancer research (01.04.2014)
Published in Clinical cancer research (01.04.2014)
Get full text
Journal Article
On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors
Morschhauser, Franck, Machiels, Jean-Pascal, Salles, Gilles, Rottey, Sylvie, Rule, Simon A J, Cunningham, David, Peyrade, Frederic, Fruchart, Christophe, Arkenau, Hendrik-Tobias, Genvresse, Isabelle, Liu, Li, Köchert, Karl, Shen, Kui, Kneip, Christoph, Peña, Carol E, Grevel, Joachim, Zhang, Jun, Cisternas, Galia, Reschke, Susanne, Granvil, Camille, Awada, Ahmad
Published in Molecular cancer therapeutics (01.02.2020)
Published in Molecular cancer therapeutics (01.02.2020)
Get full text
Journal Article
Pharmacokinetics of intravenous pan-class I phosphatidylinositol 3-kinase (PI3K) inhibitor [14C]copanlisib (BAY 80-6946) in a mass balance study in healthy male volunteers
Gerisch, Michael, Schwarz, Thomas, Lang, Dieter, Rohde, Gabriele, Reif, Stefanie, Genvresse, Isabelle, Reschke, Susanne, van der Mey, Dorina, Granvil, Camille
Published in Cancer chemotherapy and pharmacology (01.09.2017)
Published in Cancer chemotherapy and pharmacology (01.09.2017)
Get full text
Journal Article
Effects of rifampin on the pharmacokinetics of copanlisib, a novel pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor in cancer patients
Spreafico, Anna, Sawyer, Michael B., Siu, Lillian L., Huang, Funan, Reschke, Susanne, Xia, Chenghua, Yan, Zhaoping, Genvresse, Isabelle, Cisternas, Galia, Kelly, Andrea, Khan, Fatima, Reif, Stefanie, Granvil, Camille
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Pharmacodynamic Study of Copanlisib in Patients with Non-Hodgkin's Lymphoma and Advanced Solid Tumors: Confirmation of on-Target PI3K Inhibitory Activity
Morschhauser, Franck, Awada, Ahmad, Machiels, Jean-Pascal, Salles, Gilles Andre, Rottey, Sylvie, Rule, Simon, Cunningham, David, Peyrade, Frederic, Fruchart, Christophe, Arkenau, Hendrik-Tobias, Genvresse, Isabelle, Liu, Li, Kneip, Christoph, Pena, Carol, Grevel, Joachim, Zhang, Jun, Cisternas, Galia, Reschke, Susanne, Granvil, Camille
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
Get full text
Journal Article
Abstract 1288: A Phase I evaluation of safety, pharmacokinetics (PK) and pharmacodynamics (PD) of LDE225, a smoothened (Smo) antagonist, in patients with advanced solid tumors
Mita, Alain, Rodon, Jordi, Dummer, Reinhard, Baselga, Jose, Shou, Yaping, Feng, Wentao, Mahalingam, Devalingam, Thomas, Anne, Granvil, Camille, Amakye, Dereck, Tawbi, Hussein
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Get full text
Journal Article
The CYP2D6 Humanized Mouse: Effect of the Human CYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse
Corchero, Javier, Granvil, Camille P., Akiyama, Taro E., Hayhurst, Graham P., Pimprale, Satish, Feigenbaum, Lionel, Idle, Jeffrey R., Gonzalez, Frank J.
Published in Molecular pharmacology (01.12.2001)
Published in Molecular pharmacology (01.12.2001)
Get full text
Journal Article
Using chirality as a unique probe of pharmacological properties
Wainer, Irving W., Ducharme, Julie, Granvil, Camille P., Parenteau, Heli, Abdullah, Sami
Published in Journal of Chromatography A (03.03.1995)
Published in Journal of Chromatography A (03.03.1995)
Get full text
Journal Article
Comparison of Steady-State Imatinib (IM) Trough Levels, Clinical Response, and Safety Between Caucasian and Asian Patients with Chronic Lyeloid Leukemia in Chronic Phase (CML-CP) Treated with 400mg and 800mg Daily Doses of IM in the Tyrosine Kinase Inhibitor Optimization and Selectivity (TOPS) Study
Kim, Dong-Wook, Granvil, Camille, Demirhan, Eren, Reynolds, John, Jin, Yu, Wang, Yanfeng, Baccarani, Michele, Cortes-Franco, Jorge, Druker, Brian J., Hughes, Timothy P., Guilhot, François
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
Get full text
Journal Article