PDZ Domain Binding Selectivity Is Optimized Across the Mouse Proteome
Stiffler, Michael A, Chen, Jiunn R, Grantcharova, Viara P, Lei, Ying, Fuchs, Daniel, Allen, John E, Zaslavskaia, Lioudmila A, MacBeath, Gavin
Published in Science (American Association for the Advancement of Science) (20.07.2007)
Published in Science (American Association for the Advancement of Science) (20.07.2007)
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Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis
Schoeberl, Birgit, Pace, Emily A, Fitzgerald, Jonathan B, Harms, Brian D, Xu, Lihui, Nie, Lin, Linggi, Bryan, Kalra, Ashish, Paragas, Violette, Bukhalid, Raghida, Grantcharova, Viara, Kohli, Neeraj, West, Kip A, Leszczyniecka, Magdalena, Feldhaus, Michael J, Kudla, Arthur J, Nielsen, Ulrik B
Published in Science signaling (30.06.2009)
Published in Science signaling (30.06.2009)
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Effects of HER2 overexpression on cell signaling networks governing proliferation and migration
White, Forest M, Wolf-Yadlin, Alejandro, Kumar, Neil, Zhang, Yi, Hautaniemi, Sampsa, Zaman, Muhammad, Kim, Hyung-Do, Grantcharova, Viara, Lauffenburger, Douglas A
Published in Molecular systems biology (2006)
Published in Molecular systems biology (2006)
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Journal Article
Long-Range Order in the src SH3 Folding Transition State
Grantcharova, Viara P., Riddle, David S., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
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Journal Article
Experiment and theory highlight role of native state topology in SH3 folding
Baker, David, Riddle, David S, Grantcharova, Viara P, Santiago, Jed V, Alm, Eric, Ruczinski, Ingo
Published in Nature structural biology (01.11.1999)
Published in Nature structural biology (01.11.1999)
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Journal Article
Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain
Grantcharova, V P, Riddle, D S, Santiago, J V, Baker, D
Published in Nature structural biology (01.08.1998)
Published in Nature structural biology (01.08.1998)
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Journal Article
Functional rapidly folding proteins from simplified amino acid sequences
Riddle, D S, Santiago, J V, Bray-Hall, S T, Doshi, N, Grantcharova, V P, Yi, Q, Baker, D
Published in Nature structural biology (01.10.1997)
Published in Nature structural biology (01.10.1997)
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Journal Article
Simplified proteins: minimalist solutions to the ‘protein folding problem’
Plaxco, Kevin W, Riddle, David S, Grantcharova, Viara, Baker, David
Published in Current opinion in structural biology (01.02.1998)
Published in Current opinion in structural biology (01.02.1998)
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Journal Article
A Systematic Family-wide Investigation Reveals that ∼30% of Mammalian PDZ Domains Engage in PDZ-PDZ Interactions
Chang, Bryan H., Gujral, Taranjit S., Karp, Ethan S., BuKhalid, Raghida, Grantcharova, Viara P., MacBeath, Gavin
Published in Chemistry & biology (23.09.2011)
Published in Chemistry & biology (23.09.2011)
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Journal Article
Abstract LB-243: The ErbB3-targeting antibody MM-121 (seribantumab) reverses heregulin-driven resistance to multiple chemotherapies on tumor cell growth
Masson, Kristina, Grantcharova, Viara, Burenkova, Olga, Wainszelbaum, Marisa, Iadevaia, Sergio, Adams, Sharlene, Raue, Andreas, Czibere, Akos, Schoeberl, Birgit, MacBeath, Gavin
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)
Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
Published in NPJ systems biology and applications (01.01.2017)
Published in NPJ systems biology and applications (01.01.2017)
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Journal Article
Mechanisms of protein folding
Grantcharova, Viara, Alm, Eric J, Baker, David, Horwich, Arthur L
Published in Current Opinion in Structural Biology (01.02.2001)
Published in Current Opinion in Structural Biology (01.02.2001)
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Book Review
Journal Article
Abstract 1806: Efficacy of MM121 in ER+ and triple negative breast cancer studies
Nie, Lin, Burenkova, Olga, Adams, Sharlene, Kalra, Ashish, Fulgham, Aaron, Xiao, Dongmei, Grantcharova, Viara, Onsum, Matt, Wille, Lucia, Moulis, Sharon, Garcia, Gabriela, Moyo, Victor, Kubasek, Bill, Nielsen, Ulrik
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract 3756: Prediction of xenograft response to MM-121, an anti-ErbB3 inhibitor, using computational modeling and measurements of five biomarkers
Onsum, Matthew, Burenkova, Olga, Fulgham, Aaron, Nie, Lin, Kalra, Ashish, Xiao, Dongmei, Grantcharova, Viara, Adams, Sharlene, Luus, Lia, Paragas, Violette, Bukhalid, Raghida, Moulis, Sharon, Wille, Lucia, Garcia, Gabriela, Moyo, Victor, Schoeberl, Birgit, Kubasek, Bill, Nielsen, Ulrik
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Structural biology
Convery, Máire, Dennis, Caitrı́ona, Rowsell, Siân, Kuhlman, Brian, Kortemme, Tanja, Grantcharova, Viara, Engel, Andreas, Melo, Francisco, Parkinson, Gary, Russell, Rob, Newman, Richard, Flitsch, Sabine L, Lowden, Philip AS, Matthews, Steve, Stewart, Jon D
Published in Current opinion in structural biology (01.08.2000)
Published in Current opinion in structural biology (01.08.2000)
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