Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density
Chesi, Alessandra, Wagley, Yadav, Johnson, Matthew E., Manduchi, Elisabetta, Su, Chun, Lu, Sumei, Leonard, Michelle E., Hodge, Kenyaita M., Pippin, James A., Hankenson, Kurt D., Wells, Andrew D., Grant, Struan F. A.
Published in Nature communications (19.03.2019)
Published in Nature communications (19.03.2019)
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Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
Su, Chun, Johnson, Matthew E., Torres, Annabel, Thomas, Rajan M., Manduchi, Elisabetta, Sharma, Prabhat, Mehra, Parul, Le Coz, Carole, Leonard, Michelle E., Lu, Sumei, Hodge, Kenyaita M., Chesi, Alessandra, Pippin, James, Romberg, Neil, Grant, Struan F. A., Wells, Andrew D.
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Thomas, Rajan M, Pahl, Matthew C, Wang, Liqing, Grant, Struan F A, Hancock, Wayne W, Wells, Andrew D
Published in eLife (24.04.2024)
Published in eLife (24.04.2024)
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Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types
Pahl, Matthew C, Le Coz, Carole, Su, Chun, Sharma, Prabhat, Thomas, Rajan M, Pippin, James A, Cruz Cabrera, Emylette, Johnson, Matthew E, Leonard, Michelle E, Lu, Sumei, Chesi, Alessandra, Sullivan, Kathleen E, Romberg, Neil, Grant, Struan F A, Wells, Andrew D
Published in Genome Biology (03.06.2022)
Published in Genome Biology (03.06.2022)
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From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes
Wei, Zhi, Wang, Kai, Qu, Hui-Qi, Zhang, Haitao, Bradfield, Jonathan, Kim, Cecilia, Frackleton, Edward, Hou, Cuiping, Glessner, Joseph T, Chiavacci, Rosetta, Stanley, Charles, Monos, Dimitri, Grant, Struan F A, Polychronakos, Constantin, Hakonarson, Hakon
Published in PLoS genetics (01.10.2009)
Published in PLoS genetics (01.10.2009)
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A genome-wide association study on obesity and obesity-related traits
Wang, Kai, Li, Wei-Dong, Zhang, Clarence K, Wang, Zuoheng, Glessner, Joseph T, Grant, Struan F A, Zhao, Hongyu, Hakonarson, Hakon, Price, R Arlen
Published in PloS one (28.04.2011)
Published in PloS one (28.04.2011)
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genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
HAKONARSON, Hakon, GRANT, Struan F. A, LAWSON, Margaret L, ROBINSON, Luke J, SKRABAN, Robert, YANG LU, CHIAVACCI, Rosetta M, STANLEY, Charles A, KIRSCH, Susan E, RAPPAPORT, Eric F, ORANGE, Jordan S, MONOS, Dimitri S, BRADFIELD, Jonathan P, DEVOTO, Marcella, QU, Hui-Qi, POLYCHRONAKOS, Constantin, MARCHAND, Luc, KIM, Cecilia E, GLESSNER, Joseph T, GRABS, Rosemarie, CASALUNOVO, Tracy, TABACK, Shayne P, FRACKELTON, Edward C
Published in Nature (02.08.2007)
Published in Nature (02.08.2007)
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Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism
Solé-Navais, Pol, Juodakis, Julius, Ytterberg, Karin, Wu, Xiaoping, Bradfield, Jonathan P., Vaudel, Marc, LaBella, Abigail L., Helgeland, Øyvind, Flatley, Christopher, Geller, Frank, Finel, Moshe, Zhao, Mengqi, Lazarus, Philip, Hakonarson, Hakon, Magnus, Per, Andreassen, Ole A., Njølstad, Pål R., Grant, Struan F. A., Feenstra, Bjarke, Muglia, Louis J., Johansson, Stefan, Zhang, Ge, Jacobsson, Bo
Published in Nature communications (30.08.2024)
Published in Nature communications (30.08.2024)
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Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
Pahl, Matthew C, Sharma, Prabhat, Thomas, Rajan M, Thompson, Zachary, Mount, Zachary, Pippin, James A, Morawski, Peter A, Sun, Peng, Su, Chun, Campbell, Daniel, Grant, Struan F A, Wells, Andrew D
Published in eLife (20.09.2024)
Published in eLife (20.09.2024)
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Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms
Pividori, Milton, Lu, Sumei, Li, Binglan, Su, Chun, Johnson, Matthew E., Wei, Wei-Qi, Feng, Qiping, Namjou, Bahram, Kiryluk, Krzysztof, Kullo, Iftikhar J., Luo, Yuan, Sullivan, Blair D., Voight, Benjamin F., Skarke, Carsten, Ritchie, Marylyn D., Grant, Struan F. A., Greene, Casey S.
Published in Nature communications (09.09.2023)
Published in Nature communications (09.09.2023)
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Using linear and natural cubic splines, SITAR, and latent trajectory models to characterise nonlinear longitudinal growth trajectories in cohort studies
Elhakeem, Ahmed, Hughes, Rachael A, Tilling, Kate, Cousminer, Diana L, Jackowski, Stefan A, Cole, Tim J, Kwong, Alex S F, Li, Zheyuan, Grant, Struan F A, Baxter-Jones, Adam D G, Zemel, Babette S, Lawlor, Deborah A
Published in BMC medical research methodology (15.03.2022)
Published in BMC medical research methodology (15.03.2022)
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Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits
Pahl, Matthew C., Doege, Claudia A., Hodge, Kenyaita M., Littleton, Sheridan H., Leonard, Michelle E., Lu, Sumei, Rausch, Rick, Pippin, James A., De Rosa, Maria Caterina, Basak, Alisha, Bradfield, Jonathan P., Hammond, Reza K., Boehm, Keith, Berkowitz, Robert I., Lasconi, Chiara, Su, Chun, Chesi, Alessandra, Johnson, Matthew E., Wells, Andrew D., Voight, Benjamin F., Leibel, Rudolph L., Cousminer, Diana L., Grant, Struan F. A.
Published in Nature communications (19.11.2021)
Published in Nature communications (19.11.2021)
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The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5
Xia, Qianghua, Chesi, Alessandra, Manduchi, Elisabetta, Johnston, Brian T., Lu, Sumei, Leonard, Michelle E., Parlin, Ursula W., Rappaport, Eric F., Huang, Peng, Wells, Andrew D., Blobel, Gerd A., Johnson, Matthew E., Grant, Struan F. A.
Published in Diabetologia (01.11.2016)
Published in Diabetologia (01.11.2016)
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Copy number variation at 1q21.1 associated with neuroblastoma
Diskin, Sharon J., Hou, Cuiping, Glessner, Joseph T., Attiyeh, Edward F., Laudenslager, Marci, Bosse, Kristopher, Cole, Kristina, Mossé, Yaël P., Wood, Andrew, Lynch, Jill E., Pecor, Katlyn, Diamond, Maura, Winter, Cynthia, Wang, Kai, Kim, Cecilia, Geiger, Elizabeth A., McGrady, Patrick W., Blakemore, Alexandra I. F., London, Wendy B., Shaikh, Tamim H., Bradfield, Jonathan, Grant, Struan F. A., Li, Hongzhe, Devoto, Marcella, Rappaport, Eric R., Hakonarson, Hakon, Maris, John M.
Published in Nature (London) (18.06.2009)
Published in Nature (London) (18.06.2009)
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Mendelian Randomization in the Era of Genomewide Association Studies
SLEIMAN, Patrick M. A, GRANT, Struan F. A
Published in Clinical chemistry (Baltimore, Md.) (01.05.2010)
Published in Clinical chemistry (Baltimore, Md.) (01.05.2010)
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Duplication of the SLIT3 locus on 5q35.1 predisposes to major depressive disorder
Glessner, Joseph T, Wang, Kai, Sleiman, Patrick M A, Zhang, Haitao, Kim, Cecilia E, Flory, James H, Bradfield, Jonathan P, Imielinski, Marcin, Frackelton, Edward C, Qiu, Haijun, Mentch, Frank, Grant, Struan F A, Hakonarson, Hakon
Published in PloS one (01.12.2010)
Published in PloS one (01.12.2010)
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Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease
Wang, Kai, Zhang, Haitao, Kugathasan, Subra, Annese, Vito, Bradfield, Jonathan P., Russell, Richard K., Sleiman, Patrick M.A., Imielinski, Marcin, Glessner, Joseph, Hou, Cuiping, Wilson, David C., Walters, Thomas, Kim, Cecilia, Frackelton, Edward C., Lionetti, Paolo, Barabino, Arrigo, Van Limbergen, Johan, Guthery, Stephen, Denson, Lee, Piccoli, David, Li, Mingyao, Dubinsky, Marla, Silverberg, Mark, Griffiths, Anne, Grant, Struan F.A., Satsangi, Jack, Baldassano, Robert, Hakonarson, Hakon
Published in American journal of human genetics (13.03.2009)
Published in American journal of human genetics (13.03.2009)
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Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
Grant, Struan F A, Li, Mingyao, Bradfield, Jonathan P, Kim, Cecilia E, Annaiah, Kiran, Santa, Erin, Glessner, Joseph T, Casalunovo, Tracy, Frackelton, Edward C, Otieno, F George, Shaner, Julie L, Smith, Ryan M, Imielinski, Marcin, Eckert, Andrew W, Chiavacci, Rosetta M, Berkowitz, Robert I, Hakonarson, Hakon
Published in PloS one (12.03.2008)
Published in PloS one (12.03.2008)
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