Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
Pance, Katarina, Gramespacher, Josef A., Byrnes, James R., Salangsang, Fernando, Serrano, Juan-Antonio C., Cotton, Adam D., Steri, Veronica, Wells, James A.
Published in Nature biotechnology (01.02.2023)
Published in Nature biotechnology (01.02.2023)
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Journal Article
Proximity Induced Splicing Utilizing Caged Split Inteins
Gramespacher, Josef A, Burton, Antony J, Guerra, Luis F, Muir, Tom W
Published in Journal of the American Chemical Society (04.09.2019)
Published in Journal of the American Chemical Society (04.09.2019)
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Journal Article
An Atypical Mechanism of Split Intein Molecular Recognition and Folding
Stevens, Adam J, Sekar, Giridhar, Gramespacher, Josef A, Cowburn, David, Muir, Tom W
Published in Journal of the American Chemical Society (19.09.2018)
Published in Journal of the American Chemical Society (19.09.2018)
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Journal Article
Improved protein splicing using embedded split inteins
Gramespacher, Josef A., Stevens, Adam J., Thompson, Robert E., Muir, Tom W.
Published in Protein science (01.03.2018)
Published in Protein science (01.03.2018)
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Journal Article
Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2
Lim, Shion A, Gramespacher, Josef A, Pance, Katarina, Rettko, Nicholas J, Solomon, Paige, Jin, Jing, Lui, Irene, Elledge, Susanna K, Liu, Jia, Bracken, Colton J, Simmons, Graham, Zhou, Xin X, Leung, Kevin K, Wells, James A
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Abstract 1866: Discovery of mutation-independent EGFR degrading bispecific antibodies that suppress tumor growth in preclinical tumor models
Sitrin, Jonathan, Marshall, Lisa, Tran, Hai, Ng, Kenneth, Hoi, Kimberly, Gramespacher, Josef, Huang, Zhong, Goodrich, Andy, Housley, Filomena, Dayao, May, Wang, Man-Tzu, Pance, Katarina, Chen, Aleysha, Carlin, Kevin, Zhang, Lichao, Lee, James, Hannoush, Rami, Flanagan, Ken, Vinogradova, Maia, Rondon, Isaac, Gardai, Shyra
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
LOGIC GATED PROTEIN ACTUATORS
LEE, Gihoon, GRAMESPACHER, Josef, MUIR, Thomas, KOFOED, Christian, YE, Xuanjia, TAY, Nicholas, ERKALO, Girum
Year of Publication 25.04.2024
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Year of Publication 25.04.2024
Patent
LOGIC GATED PROTEIN ACTUATORS
LEE, Gihoon, GRAMESPACHER, Josef, MUIR, Thomas, KOFOED, Christian, YE, Xuanjia, TAY, Nicholas, ERKALO, Girum
Year of Publication 29.02.2024
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Year of Publication 29.02.2024
Patent
DEGRADATION OF CMET USING A BISPECIFIC BINDING AGENT
MARSHALL, Lisa, GRAMESPACHER, Josef, SITRIN, Jonathan, PANCE, Katarina, HOI, Kimberly, GARDAI, Shyra, TRAN, Hai, NG, Kenneth, HANNOUSH, Rami
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
DEGRADATION OF CMET USING A BISPECIFIC BINDING AGENT
MARSHALL, Lisa, GRAMESPACHER, Josef, SITRIN, Jonathan, PANCE, Katarina, HOI, Kimberly, GARDAI, Shyra, TRAN, Hai, NG, Kenneth, HANNOUSH, Rami
Year of Publication 23.05.2024
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Year of Publication 23.05.2024
Patent
ATYPICAL SPLIT INTEINS AND USES THEREOF
SEKAR, GIRIDHAR, GRAMESPACHER, JOSEF, COWBURN, DAVID, MUIR, TOM W, STEVENS, ADAM
Year of Publication 01.09.2022
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Year of Publication 01.09.2022
Patent
DEGRADATION OF EGFR USING A BISPECIFIC BINDING AGENT
GRAMESPACHER, Josef, MARSHALL, Lisa, SITRIN, Jonathan, PANCE, Katarina, WANG, Man-Tzu, GARDAI, Shyra, TRAN, Hai, NG, Kenneth, HANNOUSH, Rami
Year of Publication 21.03.2024
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Year of Publication 21.03.2024
Patent
DEGRADATION OF EGFR USING A BISPECIFIC BINDING AGENT
GRAMESPACHER, Josef, MARSHALL, Lisa, SITRIN, Jonathan, PANCE, Katarina, WANG, Man-Tzu, GARDAI, Shyra, TRAN, Hai, NG, Kenneth, HANNOUSH, Rami
Year of Publication 15.02.2024
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Year of Publication 15.02.2024
Patent