SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation
Whitelaw, Emma, Blewitt, Marnie E, Gendrel, Anne-Valerie, Pang, Zhenyi, Sparrow, Duncan B, Whitelaw, Nadia, Craig, Jeffrey M, Apedaile, Anwyn, Hilton, Douglas J, Dunwoodie, Sally L, Brockdorff, Neil, Kay, Graham F
Published in Nature genetics (01.05.2008)
Published in Nature genetics (01.05.2008)
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Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters
Jansz, Natasha, Keniry, Andrew, Trussart, Marie, Bildsoe, Heidi, Beck, Tamara, Tonks, Ian D, Mould, Arne W, Hickey, Peter, Breslin, Kelsey, Iminitoff, Megan, Ritchie, Matthew E, McGlinn, Edwina, Kay, Graham F, Murphy, James M, Blewitt, Marnie E
Published in Nature structural & molecular biology (01.09.2018)
Published in Nature structural & molecular biology (01.09.2018)
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Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway
Jansz, Natasha, Nesterova, Tatyana, Keniry, Andrew, Iminitoff, Megan, Hickey, Peter F., Pintacuda, Greta, Masui, Osamu, Kobelke, Simon, Geoghegan, Niall, Breslin, Kelsey A., Willson, Tracy A., Rogers, Kelly, Kay, Graham F., Fox, Archa H., Koseki, Haruhiko, Brockdorff, Neil, Murphy, James M., Blewitt, Marnie E.
Published in Cell reports (Cambridge) (13.11.2018)
Published in Cell reports (Cambridge) (13.11.2018)
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Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation
Chen, Kelan, Jiang Hu, Darcy L. Moore, Ruijie Liu, Sarah A. Kessans, Kelsey Breslin, Isabelle S. Lucet, Andrew Keniry, Huei San Leong, Clare L. Parish, Douglas J. Hilton, Richard J. L. F. Lemmers, SilveÌre M. van der Maarel, Peter E. Czabotar, Renwick C. J. Dobson, Matthew E. Ritchie, Graham F. Kay, James M. Murphy, Marnie E. Blewitt
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2015)
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Glycosylphosphatidylinositol-Anchored Serine Protease PRSS21 (Testisin) Imparts Murine Epididymal Sperm Cell Maturation and Fertilizing Ability
Netzel-Arnett, Sarah, Bugge, Thomas H, Hess, Rex A, Carnes, Kay, Stringer, Brett W, Scarman, Anthony L, Hooper, John D, Tonks, Ian D, Kay, Graham F, Antalis, Toni M
Published in Biology of reproduction (01.11.2009)
Published in Biology of reproduction (01.11.2009)
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Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation
Mould, Arne W, Pang, Zhenyi, Pakusch, Miha, Tonks, Ian D, Stark, Mitchell, Carrie, Dianne, Mukhopadhyay, Pamela, Seidel, Annica, Ellis, Jonathan J, Deakin, Janine, Wakefield, Matthew J, Krause, Lutz, Blewitt, Marnie E, Kay, Graham F
Published in Epigenetics & chromatin (02.07.2013)
Published in Epigenetics & chromatin (02.07.2013)
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Conditional Inactivation of the Men1 Gene Leads to Pancreatic and Pituitary Tumorigenesis but Does Not Affect Normal Development of These Tissues
Biondi, Christine A., Gartside, Michael G., Waring, Paul, Loffler, Kelly A., Stark, Mitchell S., Magnuson, Mark A., Kay, Graham F., Hayward, Nicholas K.
Published in Molecular and Cellular Biology (01.04.2004)
Published in Molecular and Cellular Biology (01.04.2004)
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Menin and p53 have non-synergistic effects on tumorigenesis in mice
Loffler, Kelly A, Mould, Arne W, Waring, Paul M, Hayward, Nicholas K, Kay, Graham F
Published in BMC cancer (18.06.2012)
Published in BMC cancer (18.06.2012)
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Mice Lacking the Vascular Endothelial Growth Factor-B Gene (Vegfb) Have Smaller Hearts, Dysfunctional Coronary Vasculature, and Impaired Recovery From Cardiac Ischemia
Bellomo, Daniela, Headrick, John P, Silins, Ginters U, Paterson, Carol A, Thomas, Penny S, Gartside, Michael, Mould, Arne, Cahill, Marian M, Tonks, Ian D, Grimmond, Sean M, Townson, Steve, Wells, Christine, Little, Melissa, Cummings, Margaret C, Hayward, Nicholas K, Kay, Graham F
Published in Circulation research (04.02.2000)
Published in Circulation research (04.02.2000)
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Pex13 Inactivation in the Mouse Disrupts Peroxisome Biogenesis and Leads to a Zellweger Syndrome Phenotype
Maxwell, Megan, Bjorkman, Jonas, Nguyen, Tam, Sharp, Peter, Finnie, John, Paterson, Carol, Tonks, Ian, Paton, Barbara C., Kay, Graham F., Crane, Denis I.
Published in Molecular and Cellular Biology (01.08.2003)
Published in Molecular and Cellular Biology (01.08.2003)
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Patched 1 conditional null allele in mice
Ellis, Tammy, Smyth, Ian, Riley, Emily, Graham, Scott, Elliot, Kate, Narang, Monica, Kay, Graham F., Wicking, Carol, Wainwright, Brandon
Published in Genesis (New York, N.Y. : 2000) (01.07.2003)
Published in Genesis (New York, N.Y. : 2000) (01.07.2003)
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Tissue-Specific Ablation of Prkar1a Causes Schwannomas by Suppressing Neurofibromatosis Protein Production
Jones, Georgette N., Tep, Chhavy, Towns, William H., Mihai, Georgeta, Tonks, Ian D., Kay, Graham F., Schmalbrock, Petra M., Stemmer-Rachamimov, Anat O., Yoon, Sung Ok, Kirschner, Lawrence S.
Published in Neoplasia (New York, N.Y.) (01.11.2008)
Published in Neoplasia (New York, N.Y.) (01.11.2008)
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Transgenic Overexpression of Vascular Endothelial Growth Factor-B Isoforms by Endothelial Cells Potentiates Postnatal Vessel Growth In Vivo and In Vitro
Mould, Arne W, Greco, Sonia A, Cahill, Marian M, Tonks, Ian D, Bellomo, Daniela, Patterson, Carol, Zournazi, Anna, Nash, Andrew, Scotney, Pierre, Hayward, Nicholas K, Kay, Graham F
Published in Circulation research (16.09.2005)
Published in Circulation research (16.09.2005)
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Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice
Duffy, Shannon L., Coulthard, Mark G., Spanevello, Mark D., Herath, Nirmitha I., Yeadon, Trina M., McCarron, Jennifer K., Carter, Jacinta C., Tonks, Ian D., Kay, Graham F., Phillips, Gael E., Boyd, Andrew W.
Published in Genesis (New York, N.Y. : 2000) (01.10.2008)
Published in Genesis (New York, N.Y. : 2000) (01.10.2008)
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The Glycosylphosphatidylinositol-Anchored Serine Protease PRSS21 (Testisin) Imparts Murine Epididymal Sperm Cell Maturation and Fertilizing Ability1
Netzel-Arnett, Sarah, Bugge, Thomas H, Hess, Rex A, Carnes, Kay, Stringer, Brett W, Scarman, Anthony L, Hooper, John D, Tonks, Ian D, Kay, Graham F, Antalis, Toni M
Published in Biology of reproduction (01.11.2009)
Published in Biology of reproduction (01.11.2009)
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Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues
Tonks, Ian D., Nurcombe, Victor, Paterson, Carol, Zournazi, Anna, Prather, Catherine, Mould, Arne W., Kay, Graham F.
Published in Genesis (New York, N.Y. : 2000) (01.11.2003)
Published in Genesis (New York, N.Y. : 2000) (01.11.2003)
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Journal Article
Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome
Brockdorff, Neil, Ashworth, Alan, Kay, Graham F, Cooper, Penny, Smith, Sandy, McCabe, Veronica M, Norris, Dominic P, Penny, Graeme D, Patel, Dipika, Rastan, Sohaila
Published in Nature (London) (23.05.1991)
Published in Nature (London) (23.05.1991)
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Menin Associates with a Trithorax Family Histone Methyltransferase Complex and with the Hoxc8 Locus
Hughes, Christina M., Rozenblatt-Rosen, Orit, Milne, Thomas A., Copeland, Terry D., Levine, Stuart S., Lee, Jeffrey C., Hayes, D. Neil, Shanmugam, Kalai Selvi, Bhattacharjee, Arindam, Biondi, Christine A., Kay, Graham F., Hayward, Nicholas K., Hess, Jay L., Meyerson, Matthew
Published in Molecular cell (27.02.2004)
Published in Molecular cell (27.02.2004)
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The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation
Royce-Tolland, Morgan E, Wutz, Anton, Tonks, Ian D, Kay, Graham F, Koyfman, Hannah R, Andersen, Angela A, Panning, Barbara, Talbot, Dale J
Published in Nature structural & molecular biology (01.08.2010)
Published in Nature structural & molecular biology (01.08.2010)
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