Specific olfactory deficit patterns observed in seniors and associated with cognitive decline
Camara, Gemma, Alotaibi, Majed, Lessard-Beaudoin, Melissa, Busch, Kate, Gendron, Louis, Graham, Rona K.
Published in Progress in neuro-psychopharmacology & biological psychiatry (30.08.2023)
Published in Progress in neuro-psychopharmacology & biological psychiatry (30.08.2023)
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Journal Article
Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice
Milnerwood, Austen J., Gladding, Clare M., Pouladi, Mahmoud A., Kaufman, Alexandra M., Hines, Rochelle M., Boyd, Jamie D., Ko, Rebecca W.Y., Vasuta, Oana C., Graham, Rona K., Hayden, Michael R., Murphy, Timothy H., Raymond, Lynn A.
Published in Neuron (Cambridge, Mass.) (28.01.2010)
Published in Neuron (Cambridge, Mass.) (28.01.2010)
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Journal Article
Caspase-6 and neurodegeneration
Graham, Rona K, Ehrnhoefer, Dagmar E, Hayden, Michael R
Published in Trends in neurosciences (Regular ed.) (01.12.2011)
Published in Trends in neurosciences (Regular ed.) (01.12.2011)
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Journal Article
Amelioration of Cognitive and Olfactory System Deficits in APOE4 Transgenic Mice with DHA Treatment
González, Laura Martínez, Bourissai, Adam, Lessard-Beaudoin, Mélissa, Lebel, Réjean, Tremblay, Luc, Lepage, Martin, Graham, Rona K.
Published in Molecular neurobiology (01.10.2023)
Published in Molecular neurobiology (01.10.2023)
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Journal Article
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
Talantova, Maria, Kaul, Marcus, Yao, Dongdong, Xia, Peng, Ehrnhoefer, Dagmar E, Zaidi, Rameez, Lipton, Stuart A, Graham, Rona K, Tong, Gary, Zhang, Dongxian, Clemente, Arjay, Okamoto, Shu-ichi, Hayden, Michael R, Pouladi, Mahmoud A, Vincent Chen, H-S
Published in Nature medicine (01.12.2009)
Published in Nature medicine (01.12.2009)
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Journal Article
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin
Graham, Rona K., Deng, Yu, Slow, Elizabeth J., Haigh, Brendan, Bissada, Nagat, Lu, Ge, Pearson, Jacqueline, Shehadeh, Jacqueline, Bertram, Lisa, Murphy, Zoe, Warby, Simon C., Doty, Crystal N., Roy, Sophie, Wellington, Cheryl L., Leavitt, Blair R., Raymond, Lynn A., Nicholson, Donald W., Hayden, Michael R.
Published in Cell (16.06.2006)
Published in Cell (16.06.2006)
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Journal Article
Activation of caspase‐6 and cleavage of caspase‐6 substrates is an early event in NMDA receptor–mediated excitotoxicity
Girling, Kimberly D., Demers, Marie‐Josee, Laine, Jean, Zhang, Shu, Wang, Yu Tian, Graham, Rona K.
Published in Journal of neuroscience research (01.03.2018)
Published in Journal of neuroscience research (01.03.2018)
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Journal Article
Full length mutant huntingtin is required for altered Ca signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease
Zhang, Hua, Li, Qin, Graham, Rona K, Slow, Elizabeth, Hayden, Michael R, Bezprozvanny, Ilya
Published in Neurobiology of disease (01.07.2008)
Published in Neurobiology of disease (01.07.2008)
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Journal Article
Diet enriched in omega‐3 fatty acids alleviates olfactory system deficits in APOE4 transgenic mice
Lessard‐Beaudoin, Melissa, M. Gonzalez, Laura, AlOtaibi, Majed, Chouinard‐Watkins, Raphaël, Plourde, Melanie, Calon, Frederic, Graham, Rona K.
Published in The European journal of neuroscience (01.11.2021)
Published in The European journal of neuroscience (01.11.2021)
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Journal Article
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models
Marco, Sonia, Giralt, Albert, Petrovic, Milos M, Pouladi, Mahmoud A, Martínez-Turrillas, Rebeca, Martínez-Hernández, José, Kaltenbach, Linda S, Torres-Peraza, Jesús, Graham, Rona K, Watanabe, Masahiko, Luján, Rafael, Nakanishi, Nobuki, Lipton, Stuart A, Lo, Donald C, Hayden, Michael R, Alberch, Jordi, Wesseling, John F, Pérez-Otaño, Isabel
Published in Nature medicine (01.08.2013)
Published in Nature medicine (01.08.2013)
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Journal Article
Prolongation of Action Potential Duration and QT Interval During Epilepsy Linked to Increased Contribution of Neuronal Sodium Channels to Cardiac Late Na+ Current: Potential Mechanism for Sudden Death in Epilepsy
Biet, Michael, Morin, Nathalie, Lessard-Beaudoin, Melissa, Graham, Rona K, Duss, Sandra, Gagné, Jonathan, Sanon, Nathalie T, Carmant, Lionel, Dumaine, Robert
Published in Circulation. Arrhythmia and electrophysiology (01.08.2015)
Published in Circulation. Arrhythmia and electrophysiology (01.08.2015)
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Journal Article
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice
Wong, Bibiana K.Y, Ehrnhoefer, Dagmar E, Graham, Rona K, Martin, Dale D.O, Ladha, Safia, Uribe, Valeria, Stanek, Lisa M, Franciosi, Sonia, Qiu, Xiaofan, Deng, Yu, Kovalik, Vlad, Zhang, Weining, Pouladi, Mahmoud A, Shihabuddin, Lamya S, Hayden, Michael R
Published in Neurobiology of disease (01.04.2015)
Published in Neurobiology of disease (01.04.2015)
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Journal Article
Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease
Zhang, Hua, Li, Qin, Graham, Rona K, Slow, Elizabeth, Hayden, Michael R, Bezprozvanny, Ilya
Published in Neurobiology of disease (01.07.2008)
Published in Neurobiology of disease (01.07.2008)
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Journal Article
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease
Wang, Chuan-En, Tydlacka, Suzanne, Orr, Adam L., Yang, Shang-Hsun, Graham, Rona K., Hayden, Michael R., Li, Shihua, Chan, Anthony W.S., Li, Xiao-Jiang
Published in Human molecular genetics (01.09.2008)
Published in Human molecular genetics (01.09.2008)
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Journal Article
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin
Pouladi, Mahmoud A., Graham, Rona K., Karasinska, Joanna M., Xie, Yuanyun, Santos, Rachelle Dar, Petersén, Åsa, Hayden, Michael R.
Published in Brain (London, England : 1878) (01.04.2009)
Published in Brain (London, England : 1878) (01.04.2009)
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Journal Article
Absence of Behavioral Abnormalities and Neurodegeneration in vivo despite Widespread Neuronal Huntingtin Inclusions
Slow, Elizabeth J., Graham, Rona K., Osmand, Alexander P., Devon, Rebecca S., Lu, Ge, Deng, Yu, Pearson, Jacqui, Vaid, Kuljeet, Bissada, Nagat, Wetzel, Ronald, Leavitt, Blair R., Hayden, Michael R., Palmiter, Richard D.
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2005)
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Journal Article
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
Butland, Stefanie L, Sanders, Shaun S, Schmidt, Mandi E, Riechers, Sean-Patrick, Lin, David T S, Martin, Dale D O, Vaid, Kuljeet, Graham, Rona K, Singaraja, Roshni R, Wanker, Erich E, Conibear, Elizabeth, Hayden, Michael R
Published in Human molecular genetics (01.08.2014)
Published in Human molecular genetics (01.08.2014)
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