227-LB: GLP-1 Activation of HCN Channels Increases Glucose-Stimulated β- and δ- Cell Ca2+ Oscillation Frequency
ZABORSKA, KAROLINA E., JORDAN, KELLI L., DADI, PRASANNA, DICKERSON, MATTHEW, GRAFF, SARAH M., JACOBSON, DAVID
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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Tetraspanin‐7 regulation of L‐type voltage‐dependent calcium channels controls pancreatic β‐cell insulin secretion
Dickerson, Matthew T., Dadi, Prasanna K., Butterworth, Regan B., Nakhe, Arya Y., Graff, Sarah M., Zaborska, Karolina E., Schaub, Charles M., Jacobson, David A.
Published in The Journal of physiology (01.11.2020)
Published in The Journal of physiology (01.11.2020)
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Journal Article
TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet
Graff, Sarah M., Nakhe, Arya Y., Dadi, Prasanna K., Dickerson, Matthew T., Dobson, Jordyn R., Zaborska, Karolina E., Ibsen, Chloe E., Butterworth, Regan B., Vierra, Nicholas C., Jacobson, David A.
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, Bess P., Li, Qing V., Cho, Hyein S., Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R., Kale, Hanuman T., Kaplan, Samuel J., Beer, Michael A., Sidoli, Simone, Huangfu, Danwei
Published in Nature communications (17.10.2024)
Published in Nature communications (17.10.2024)
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TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced β-cell proliferation
Altman, Molly K, Schaub, Charles M, Dadi, Prasanna K, Dickerson, Matthew T, Zaborska, Karolina E, Nakhe, Arya Y, Graff, Sarah M, Galletta, Thomas J, Amarnath, Gautami, Thorson, Ariel S, Gu, Guoqiang, Jacobson, David A
Published in Development (Cambridge) (15.08.2021)
Published in Development (Cambridge) (15.08.2021)
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Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response
Yang, Xiaodun, Graff, Sarah M., Heiser, Cody N., Ho, Kung-Hsien, Chen, Bob, Simmons, Alan J., Southard-Smith, Austin N., David, Gregory, Jacobson, David A., Kaverina, Irina, Wright, Christopher V.E., Lau, Ken S., Gu, Guoqiang
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young
Graff, Sarah M, Johnson, Stephanie R, Leo, Paul J, Dadi, Prasanna K, Dickerson, Matthew T, Nakhe, Arya Y, McInerney-Leo, Aideen M, Marshall, Mhairi, Zaborska, Karolina E, Schaub, Charles M, Brown, Matthew A, Jacobson, David A, Duncan, Emma L
Published in JCI insight (08.07.2021)
Published in JCI insight (08.07.2021)
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Lactate activation of α-cell KATP channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca2+ entry
Zaborska, Karolina E., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., Thorson, Ariel S., Schaub, Charles M., Graff, Sarah M., Stanley, Jade E., Kondapavuluru, Roy S., Denton, Jerod S., Jacobson, David A.
Published in Molecular metabolism (Germany) (01.12.2020)
Published in Molecular metabolism (Germany) (01.12.2020)
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TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury
Shafit-Zagardo, Bridget, Sidoli, Simone, Goldman, James E, DuBois, Juwen C, Corboy, John R, Strittmatter, Stephen M, Guzik, Hillary, Edema, Ukuemi, Arackal, Anita G, Botbol, Yair M, Merheb, Emilio, Nagra, Rashed M, Graff, Sarah
Published in Cells (Basel, Switzerland) (27.06.2023)
Published in Cells (Basel, Switzerland) (27.06.2023)
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RNA polymerase II promotes the organization of chromatin following DNA replication
Bandau, Susanne, Alvarez, Vanesa, Jiang, Hao, Graff, Sarah, Sundaramoorthy, Ramasubramanian, Gierlinski, Marek, Toman, Matt, Owen-Hughes, Tom, Sidoli, Simone, Lamond, Angus, Alabert, Constance
Published in EMBO reports (12.03.2024)
Published in EMBO reports (12.03.2024)
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Use of cardiac cell cultures from salmonids to measure the cardiotoxic effect of environmental pollutants
Krebs, Torben, Bauer, Julia, Graff, Sarah, Teich, Lukas, Sterneberg, Markus, Gebert, Marina, Seibel, Henrike, Seeger, Bettina, Steinhagen, Dieter, Jung-Schroers, Verena, Adamek, Mikolaj
Published in Journal of fish diseases (29.09.2024)
Published in Journal of fish diseases (29.09.2024)
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Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
Galbo, Jr, Phillip M, Madsen, Anne Tranberg, Liu, Yang, Peng, Mou, Wei, Yao, Ciesielski, Michael J, Fenstermaker, Robert A, Graff, Sarah, Montagna, Cristina, Segall, Jeffrey E, Sidoli, Simone, Zang, Xingxing, Zheng, Deyou
Published in Clinical cancer research (16.02.2024)
Published in Clinical cancer research (16.02.2024)
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40-OR: The Role of TALK-1 K+ Channels in Pancreatic ß-Cell Insulin Secretion, Mitochondrial Function, and the ER Stress Response
GRAFF, SARAH M., DADI, PRASANNA, IBSEN, CHLOE E., DICKERSON, MATTHEW, JORDAN, KELLI L., JACOBSON, DAVID
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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MODELING REACTIVATED HETEROCHROMATIN USING AN AGING 3D CELL MODEL
Sidoli, Simone, Stransky, Stephanie, Cutler, Ronald, Graff, Sarah, Aguilan, Jennifer
Published in Innovation in aging (20.12.2022)
Published in Innovation in aging (20.12.2022)
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