Pharmacokinetics, metabolism and safety of deuterated L‐DOPA (SD‐1077)/carbidopa compared to L‐DOPA/carbidopa following single oral dose administration in healthy subjects
Schneider, Frank, Erisson, Lavi, Beygi, Hooman, Bradbury, Margaret, Cohen‐Barak, Orit, Grachev, Igor D., Guzy, Serge, Loupe, Pippa S., Levi, Micha, McDonald, Mirna, Savola, Juha‐Matti, Papapetropoulos, Spyros, Tracewell, William G., Velinova, Maria, Spiegelstein, Ofer
Published in British journal of clinical pharmacology (01.10.2018)
Published in British journal of clinical pharmacology (01.10.2018)
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Journal Article
Characterizing patient compliance over six months in remote digital trials of Parkinson's and Huntington disease
Cohen, Shani, Waks, Zeev, Elm, Jordan J, Gordon, Mark Forrest, Grachev, Igor D, Navon-Perry, Leehee, Fine, Shai, Grossman, Iris, Papapetropoulos, Spyros, Savola, Juha-Matti
Published in BMC medical informatics and decision making (20.12.2018)
Published in BMC medical informatics and decision making (20.12.2018)
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Journal Article
Quantification of Motor Function in Huntington Disease Patients Using Wearable Sensor Devices
Gordon, Mark Forrest, Grachev, Igor D., Mazeh, Itzik, Dolan, Yonatan, Reilmann, Ralf, Loupe, Pippa S., Fine, Shai, Navon-Perry, Leehee, Gross, Nicholas, Papapetropoulos, Spyros, Savola, Juha-Matti, Hayden, Michael R.
Published in Digital biomarkers (01.09.2019)
Published in Digital biomarkers (01.09.2019)
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Clinical utility of dopamine transporter single photon emission CT (DaT-SPECT) with (123I) ioflupane in diagnosis of parkinsonian syndromes
Bajaj, Nin, Hauser, Robert A, Grachev, Igor D
Published in Journal of Neurology, Neurosurgery and Psychiatry (01.11.2013)
Published in Journal of Neurology, Neurosurgery and Psychiatry (01.11.2013)
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Journal Article
Book Review
Prospective Flutemetamol Positron Emission Tomography and Histopathology in Normal Pressure Hydrocephalus
Rinne, Juha O., Frantzen, Janek, Leinonen, Ville, Lonnrot, Kimmo, Laakso, Aki, Virtanen, Kirsi A., Solin, Olof, Kotkansalo, Anna, Koivisto, Anne, Sajanti, Juha, Karppinen, Atte, Lehto, Hanna, Rummukainen, Jaana, Buckley, Chris, Smith, Adrian, Jones, Paul A., Sherwin, Paul, Farrar, Gill, McLain, Richard, Kailajarvi, Marita, Grachev, Igor D.
Published in Neuro-degenerative diseases (2014)
Published in Neuro-degenerative diseases (2014)
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Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density
Curtis, Craig, Gamez, Jose E, Singh, Upinder, Sadowsky, Carl H, Villena, Teresa, Sabbagh, Marwan N, Beach, Thomas G, Duara, Ranjan, Fleisher, Adam S, Frey, Kirk A, Walker, Zuzana, Hunjan, Arvinder, Holmes, Clive, Escovar, Yavir M, Vera, Carla X, Agronin, Marc E, Ross, Joel, Bozoki, Andrea, Akinola, Mary, Shi, Jiong, Vandenberghe, Rik, Ikonomovic, Milos D, Sherwin, Paul F, Grachev, Igor D, Farrar, Gillian, Smith, Adrian P L, Buckley, Christopher J, McLain, Richard, Salloway, Stephen
Published in JAMA neurology (01.03.2015)
Published in JAMA neurology (01.03.2015)
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Journal Article
Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study
Grachev, Igor D., Meyer, Philipp M., Becker, Georg A., Bronzel, Marcus, Marsteller, Doug, Pastino, Gina, Voges, Ole, Rabinovich, Laura, Knebel, Helena, Zientek, Franziska, Rullmann, Michael, Sattler, Bernhard, Patt, Marianne, Gerhards, Thilo, Strauss, Maria, Kluge, Andreas, Brust, Peter, Savola, Juha-Matti, Gordon, Mark F., Geva, Michal, Hesse, Swen, Barthel, Henryk, Hayden, Michael R., Sabri, Osama
Published in European journal of nuclear medicine and molecular imaging (01.04.2021)
Published in European journal of nuclear medicine and molecular imaging (01.04.2021)
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Impact of DaTscan SPECT imaging on clinical management, diagnosis, confidence of diagnosis, quality of life, health resource use and safety in patients with clinically uncertain parkinsonian syndromes: a prospective 1-year follow-up of an open-label controlled study
Kupsch, Andreas R, Bajaj, Nin, Weiland, Frederick, Tartaglione, Antonio, Klutmann, Susanne, Buitendyk, Melanie, Sherwin, Paul, Tate, Ann, Grachev, Igor D
Published in Journal of neurology, neurosurgery and psychiatry (01.06.2012)
Published in Journal of neurology, neurosurgery and psychiatry (01.06.2012)
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Journal Article
[18F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid β detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies
Rinne, Juha O., Wong, Dean F., Wolk, David A., Leinonen, Ville, Arnold, Steven E., Buckley, Chris, Smith, Adrian, McLain, Richard, Sherwin, Paul F., Farrar, Gill, Kailajärvi, Marita, Grachev, Igor D.
Published in Acta neuropathologica (01.12.2012)
Published in Acta neuropathologica (01.12.2012)
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Journal Article
A Method for Assessing the Accuracy of Intersubject Registration of the Human Brain Using Anatomic Landmarks
Grachev, Igor D., Berdichevsky, Dmitriy, Rauch, Scott L., Heckers, Stephan, Kennedy, David N., Caviness, Verne S., Alpert, Nathaniel M.
Published in NeuroImage (Orlando, Fla.) (01.02.1999)
Published in NeuroImage (Orlando, Fla.) (01.02.1999)
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Journal Article
Additional Safety and Exploratory Efficacy Data at 48 and 60 Months from Open-HART, an Open-Label Extension Study of Pridopidine in Huntington Disease
McGarry, Andrew, Auinger, Peggy, Kieburtz, Karl, Geva, Michal, Mehra, Munish, Abler, Victor, Grachev, Igor D, Gordon, Mark Forrest, Savola, Juha-Matti, Gandhi, Sanjay, Papapetropoulos, Spyridon, Hayden, Michael
Published in Journal of Huntington's disease (01.01.2020)
Published in Journal of Huntington's disease (01.01.2020)
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Journal Article
Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease
McGarry, Andrew, Kieburtz, Karl, Abler, Victor, Grachev, Igor D, Gandhi, Sanjay, Auinger, Peggy, Papapetropoulos, Spyridon, Hayden, Michael
Published in Journal of Huntington's disease (01.01.2017)
Published in Journal of Huntington's disease (01.01.2017)
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Journal Article
Is ioflupane I123 injection diagnostically effective in patients with movement disorders and dementia? Pooled analysis of four clinical trials
O'Brien, John T, Oertel, Wolfgang H, McKeith, Ian G, Grosset, Donald G, Walker, Zuzana, Tatsch, Klaus, Tolosa, Eduardo, Sherwin, Paul F, Grachev, Igor D
Published in BMJ open (03.07.2014)
Published in BMJ open (03.07.2014)
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Journal Article
Prerequisites to launch neuroprotective trials in Parkinson's disease: An industry perspective
Streffer, Johannes R., Grachev, Igor D., Fitzer-Attas, Cheryl, Gomez-Mancilla, Baltazar, Boroojerdi, Babak, Bronzova, Juliana, Ostrowitzki, Susanne, Victor, Stephen J., Fontoura, Paulo, Alexander, Robert
Published in Movement disorders (15.04.2012)
Published in Movement disorders (15.04.2012)
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Journal Article
An In Vivo Evaluation of Cerebral Cortical Amyloid with [18F]Flutemetamol Using Positron Emission Tomography Compared with Parietal Biopsy Samples in Living Normal Pressure Hydrocephalus Patients
Wong, Dean F., Moghekar, Abhay R., Rigamonti, Daniele, Brašić, James R., Rousset, Olivier, Willis, William, Buckley, Chris, Smith, Adrian, Gok, Beril, Sherwin, Paul, Grachev, Igor D.
Published in Molecular imaging and biology (01.04.2013)
Published in Molecular imaging and biology (01.04.2013)
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An in vivo [ 18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam
Goffin, Karolien, Bormans, Guy, Casteels, Cindy, Bosier, Barbara, Lambert, Didier M., Grachev, Igor D., Van Paesschen, Wim, Van Laere, Koen
Published in Neuropharmacology (01.06.2008)
Published in Neuropharmacology (01.06.2008)
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