Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1
Ragunathan, Priya, Dick, Thomas, Grüber, Gerhard
Published in Antimicrobial agents and chemotherapy (17.05.2022)
Published in Antimicrobial agents and chemotherapy (17.05.2022)
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Crystal Structure of the NS3 Protease-Helicase from Dengue Virus
DAHAI LUO, TING XU, HUNKE, Cornelia, GRÜBER, Gerhard, VASUDEVAN, Subhash G, LESCAR, Julien
Published in Journal of Virology (01.01.2008)
Published in Journal of Virology (01.01.2008)
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Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery
Harikishore, Amaravadhi, Mathiyazakan, Vikneswaran, Pethe, Kevin, Grüber, Gerhard
Published in Expert opinion on drug discovery (03.08.2023)
Published in Expert opinion on drug discovery (03.08.2023)
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Variations of the Mycobacterium abscessus F-ATP synthase subunit a-c interface alter binding and potency of the anti-TB drug bedaquiline
Krah, Alexander, Ragunathan, Priya, Bond, Peter J, Grüber, Gerhard
Published in Biochemical and biophysical research communications (01.01.2024)
Published in Biochemical and biophysical research communications (01.01.2024)
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Eukaryotic V-ATPase: Novel structural findings and functional insights
Marshansky, Vladimir, Rubinstein, John L., Grüber, Gerhard
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Cryo-EM structure of the Mycobacterium abscessus F1-ATPase
Wong, Chui-Fann, Leow, Chen-Yen, Grüber, Gerhard
Published in Biochemical and biophysical research communications (03.09.2023)
Published in Biochemical and biophysical research communications (03.09.2023)
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Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI
Mathiyazakan, Vikneswaran, Wong, Chui-Fann, Harikishore, Amaravadhi, Pethe, Kevin, Grüber, Gerhard
Published in Antimicrobial agents and chemotherapy (15.06.2023)
Published in Antimicrobial agents and chemotherapy (15.06.2023)
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Pyrazinamide triggers degradation of its target aspartate decarboxylase
Gopal, Pooja, Sarathy, Jickky Palmae, Yee, Michelle, Ragunathan, Priya, Shin, Joon, Bhushan, Shashi, Zhu, Junhao, Akopian, Tatos, Kandror, Olga, Lim, Teck Kwang, Gengenbacher, Martin, Lin, Qingsong, Rubin, Eric J., Grüber, Gerhard, Dick, Thomas
Published in Nature communications (03.04.2020)
Published in Nature communications (03.04.2020)
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TBAJ-876 Retains Bedaquiline's Activity against Subunits c and ε of Mycobacterium tuberculosis F-ATP Synthase
Sarathy, Jickky Palmae, Ragunathan, Priya, Shin, Joon, Cooper, Christopher B, Upton, Anna M, Grüber, Gerhard, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (01.10.2019)
Published in Antimicrobial agents and chemotherapy (01.10.2019)
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Atomic solution structure of Mycobacterium abscessus F‐ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor
Shin, Joon, Harikishore, Amaravadhi, Wong, Chui Fann, Ragunathan, Priya, Dick, Thomas, Grüber, Gerhard
Published in The FEBS journal (01.10.2022)
Published in The FEBS journal (01.10.2022)
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Active site C P -loop dynamics modulate substrate binding, catalysis, oligomerization, stability, over-oxidation and recycling of 2-Cys Peroxiredoxins
Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
Published in Free radical biology & medicine (01.04.2018)
Published in Free radical biology & medicine (01.04.2018)
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Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase
Harikishore, Amaravadhi, Chong, Sherilyn Shi Min, Ragunathan, Priya, Bates, Roderick W., Grüber, Gerhard
Published in Molecular diversity (01.02.2021)
Published in Molecular diversity (01.02.2021)
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SQ31f is a potent non-tuberculous mycobacteria antibiotic by specifically targeting the mycobacterial F-ATP synthase
Ragunathan, Priya, Sae-Lao, Patcharaporn, Harikishore, Amaravadhi, Daher, Wassim, Roquet-Banères, Françoise, Kremer, Laurent, Bates, Roderick W, Grüber, Gerhard
Published in Journal of antimicrobial chemotherapy (05.11.2024)
Published in Journal of antimicrobial chemotherapy (05.11.2024)
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Atomic structure of the regulatory TGS domain of Rel protein from Mycobacterium tuberculosis and its interaction with deacylated tRNA
Shin, Joon, Singal, Bharti, Grüber, Ardina, Wong, David Meng Kit, Ragunathan, Priya, Grüber, Gerhard
Published in FEBS letters (01.12.2021)
Published in FEBS letters (01.12.2021)
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TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity
Sarathy, Jickky Palmae, Ragunathan, Priya, Cooper, Christopher B, Upton, Anna M, Grüber, Gerhard, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (27.01.2020)
Published in Antimicrobial agents and chemotherapy (27.01.2020)
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