Alirocumab boosts antioxidant status and halts inflammation in rat model of sepsis-induced nephrotoxicity via modulation of Nrf2/HO-1, PCSK9/HMGB1/NF-ᴋB/NLRP3 and Fractalkine/CX3CR1 hubs
Hassan, Noha F., El-Ansary, Mona R., Selim, Heba Mohammed Refat M., Ousman, Mona S., Khattab, Marwa S., El-Ansary, Mahmoud R.M., Gad, Enas S., Moursi, Suzan M.M., Gohar, Asmaa, Gowifel, Ayah M.H.
Published in Biomedicine & pharmacotherapy (01.08.2024)
Published in Biomedicine & pharmacotherapy (01.08.2024)
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The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways
Abu-Elfotuh, Karema, Selim, Heba Mohammed Refat M., Riad, Omnia Karem M., Hamdan, Ahmed M. E., Hassanin, Soha Osama, Sharif, Asmaa F., Moustafa, Nouran Magdy, Gowifel, Ayah M.H., Mohamed, Marwa Y. A., Atwa, Ahmed M., Zaghlool, Sameh S., El-Din, Mahmoud Nour
Published in Frontiers in pharmacology (02.08.2023)
Published in Frontiers in pharmacology (02.08.2023)
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A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets: Involvement of PI3K/AKT/GSK-3β/CREB, PERK/CHOP/Bcl-2, and AMPK/SIRT-1/mTOR Axes
Hassan, Yassmin Raafat, El-Shiekh, Riham A., El Hefnawy, Hala M., Mohamed, Osama G., Abu-Elfotuh, Karema, Hamdan, Ahmed M., Darwish, Alshaymaa, Gowifel, Ayah M.H., Tripathi, Ashootosh, Michael, Camilia George
Published in Journal of ethnopharmacology (24.04.2024)
Published in Journal of ethnopharmacology (24.04.2024)
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The potential anti-Alzheimer's activity of Oxalis corniculata Linn. Methanolic extract in experimental rats: Role of APOE4/LRP1, TLR4/NF-κβ/NLRP3, Wnt 3/β-catenin/GSK-3β, autophagy and apoptotic cues
Abu-Elfotuh, Karema, Hamdan, Ahmed M.E., Mohamed, Shaza A., Bakr, Riham O., Ahmed, Amal H., Atwa, Ahmed M., Hamdan, Amira M., Alanzai, Ahad Ghanem, Alnahhas, Raghad Khalid, Gowifel, Ayah M.H., Salem, Maha A.
Published in Journal of ethnopharmacology (24.04.2024)
Published in Journal of ethnopharmacology (24.04.2024)
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Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis in rats: impact on TGF-β/Smad3 and NF-κB signaling pathways
Gowifel, Ayah M. H., Khalil, Mona G., Nada, Somaia A., Kenawy, Sanaa A., Ahmed, Kawkab A., Salama, Maha M., Safar, Marwa M.
Published in Toxicology mechanisms and methods (12.10.2020)
Published in Toxicology mechanisms and methods (12.10.2020)
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Neuroprotective Effects of Some Nutraceuticals against Manganese-Induced Parkinson's Disease in Rats: Possible Modulatory Effects on TLR4/NLRP3/NF-κB, GSK-3β, Nrf2/HO-1, and Apoptotic Pathways
Abu-Elfotuh, Karema, Hamdan, Ahmed Mohsen Elsaid, Mohammed, Asmaa A, Atwa, Ahmed M, Kozman, Magy R, Ibrahim, Amany M, Motawea, Shaimaa M, Selim, Heba Mohammed Refat M, Tohamy, Sally Tohamy Kamal, Nour El-Din, Mahmoud, Zaghlool, Sameh S, Gowifel, Ayah M H, Awny, Magdy M
Published in Pharmaceuticals (Basel, Switzerland) (01.12.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.12.2022)
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Punicalagin’s Protective Effects on Parkinson’s Progression in Socially Isolated and Socialized Rats: Insights into Multifaceted Pathway
Salem, Hoda A, Abu-Elfotuh, Karema, Alzahrani, Sharifa, Rizk, Nermin I, Ali, Howaida S, Elsherbiny, Nehal, Aljohani, Alhanouf, Hamdan, Ahmed M. E, Chellasamy, Panneerselvam, Abdou, Nada S, Gowifel, Ayah M. H, Darwish, Alshaymaa, Ibrahim, Osama Mohamed, Abd Elmageed, Zakaria Y
Published in Pharmaceutics (01.10.2023)
Published in Pharmaceutics (01.10.2023)
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Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways
Abu-Elfotuh, Karema, Tolba, Amina M. A, Hussein, Furqan H, Hamdan, Ahmed M. E, Rabeh, Mohamed A, Alshahri, Saad A, Ali, Azza A, Mosaad, Sarah M, Mahmoud, Nihal A, Elsaeed, Magdy Y, Abdelglil, Ranya M, El-Awady, Rehab R, Galal, Eman Reda M, Kamal, Mona M, Elsisi, Ahmed M. M, Darwish, Alshaymaa, Gowifel, Ayah M. H, Mahran, Yasmen F
Published in Pharmaceutics (31.07.2023)
Published in Pharmaceutics (31.07.2023)
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