A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease
Todd, Daniel, Gowers, Ian, Dowler, Simon J, Wall, Michael D, McAllister, George, Fischer, David F, Dijkstra, Sipke, Fratantoni, Silvina A, van de Bospoort, Rhea, Veenman-Koepke, Jessica, Flynn, Geraldine, Arjomand, Jamshid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Wityak, John, Bard, Jonathan A
Published in PloS one (04.02.2014)
Published in PloS one (04.02.2014)
Get full text
Journal Article
Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)
Martínez-Botella, Gabriel, Breen, John N, Duffy, James E. S, Dumas, Jacques, Geng, Bolin, Gowers, Ian K, Green, Oluyinka M, Guler, Satenig, Hentemann, Martin F, Hernandez-Juan, Felix A, Joseph-McCarthy, Diane, Kawatkar, Sameer, Larsen, Nicholas A, Lazari, Ovadia, Loch, James T, Macritchie, Jacqueline A, McKenzie, Andrew R, Newman, Joseph V, Olivier, Nelson B, Otterson, Linda G, Owens, Andrew P, Read, Jon, Sheppard, David W, Keating, Thomas A
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
Get full text
Journal Article
Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery
Lachize, Servane, Bospoort, Rhea van de, Silva, Marta da Silva da, Steentraten, Niki van der, Gowers, Ian, Clark, Roger, DeGroot, Jeroen, Waddell, Ian, Schiewe, Hajo, Jain, Shushant
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods
Sharma, Raman, Lawrenson, Alexandre S, Fisher, Nicholas E, Warman, Ashley J, Shone, Alison E, Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet, Gibbons, Peter, Hong, David W, Stocks, Paul, Nixon, Gemma L, Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P, O'Neill, Paul M, Ward, Stephen A, Biagini, Giancarlo A, Berry, Neil G
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
Get full text
Journal Article