Germline BRCA1 mutations increase prostate cancer risk
Leongamornlert, D, Mahmud, N, Tymrakiewicz, M, Saunders, E, Dadaev, T, Castro, E, Goh, C, Govindasami, K, Guy, M, O'Brien, L, Sawyer, E, Hall, A, Wilkinson, R, Easton, D, Goldgar, D, Eeles, R, Kote-Jarai, Z
Published in British journal of cancer (08.05.2012)
Published in British journal of cancer (08.05.2012)
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Journal Article
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease
Leongamornlert, D, Saunders, E, Dadaev, T, Tymrakiewicz, M, Goh, C, Jugurnauth-Little, S, Kozarewa, I, Fenwick, K, Assiotis, I, Barrowdale, D, Govindasami, K, Guy, M, Sawyer, E, Wilkinson, R, Antoniou, A C, Eeles, R, Kote-Jarai, Z
Published in British journal of cancer (18.03.2014)
Published in British journal of cancer (18.03.2014)
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Journal Article
Prevalence of the HOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes
Kote-Jarai, Z, Mikropoulos, C, Leongamornlert, D A, Dadaev, T, Tymrakiewicz, M, Saunders, E J, Jones, M, Jugurnauth-Little, S, Govindasami, K, Guy, M, Hamdy, F C, Donovan, J L, Neal, D E, Lane, J A, Dearnaley, D, Wilkinson, R A, Sawyer, E J, Morgan, A, Antoniou, A C, Eeles, R A
Published in Annals of oncology (01.04.2015)
Published in Annals of oncology (01.04.2015)
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Journal Article
High burden of copy number alterations and c-MYC amplification in prostate cancer from BRCA2 germline mutation carriers
Castro, E., Jugurnauth-Little, S., Karlsson, Q., Al-Shahrour, F., Piñeiro-Yañez, E., Van de Poll, F., Leongamornlert, D., Dadaev, T., Govindasami, K., Guy, M., Eeles, R., Kote-Jarai, Z.
Published in Annals of oncology (01.11.2015)
Published in Annals of oncology (01.11.2015)
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Journal Article
Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases
FitzGerald, L. M., Zhao, S., Leonardson, A., Geybels, M. S., Kolb, S., Lin, D. W., Wright, J. L., Eeles, R., Kote-Jarai, Z., Govindasami, K., Giles, G. G., Southey, M. C., Schleutker, J., Tammela, T. L., Sipeky, C., Penney, K. L., Stampfer, M. J., Gronberg, H., Wiklund, F., Stattin, P., Hugosson, J., Karyadi, D. M., Ostrander, E. A., Feng, Z., Stanford, J. L.
Published in Prostate cancer and prostatic diseases (01.06.2018)
Published in Prostate cancer and prostatic diseases (01.06.2018)
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Journal Article
DNA repair gene panel mutations in young onset and aggressive vs non aggressive prostate cancer cases in the UK
Eeles, R., Saunders, E., Wakerell, S., Whitmore, I., Cieza-Borrella, C., Govindasami, K., Dadaev, T., Kote-Jarai, Z., Leongamornlert, D.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
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Journal Article
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression
Kote-Jarai, Zsofia, Saunders, Edward J, Leongamornlert, Daniel A, Tymrakiewicz, Malgorzata, Dadaev, Tokhir, Jugurnauth-Little, Sarah, Ross-Adams, Helen, Al Olama, Ali Amin, Benlloch, Sara, Halim, Silvia, Russell, Roslin, Russel, Roslin, Dunning, Alison M, Luccarini, Craig, Dennis, Joe, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Muir, Ken, Giles, Graham G, Severi, Gianluca, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schumacher, Fredrick, Henderson, Brian E, Le Marchand, Loic, Lindstrom, Sara, Kraft, Peter, Hunter, David J, Gapstur, Susan, Chanock, Stephen, Berndt, Sonja I, Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Canzian, Federico, Riboli, Elio, Key, Tim J, Travis, Ruth C, Campa, Daniele, Ingles, Sue A, John, Esther M, Hayes, Richard B, Pharoah, Paul, Khaw, Kay-Tee, Stanford, Janet L, Ostrander, Elaine A, Signorello, Lisa B, Thibodeau, Stephen N, Schaid, Dan, Maier, Christiane, Vogel, Walther, Kibel, Adam S, Cybulski, Cezary, Lubinski, Jan, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y, Kaneva, Radka, Batra, Jyotsna, Spurdle, Amanda, Clements, Judith A, Teixeira, Manuel R, Govindasami, Koveela, Guy, Michelle, Wilkinson, Rosemary A, Sawyer, Emma J, Morgan, Angela, Dicks, Ed, Baynes, Caroline, Conroy, Don, Bojesen, Stig E, Kaaks, Rudolf, Vincent, Daniel, Bacot, François, Tessier, Daniel C, Easton, Douglas F, Eeles, Rosalind A
Published in Human molecular genetics (15.06.2013)
Published in Human molecular genetics (15.06.2013)
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Journal Article
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array
Saunders, Edward J, Dadaev, Tokhir, Leongamornlert, Daniel A, Olama, Ali Amin Al, Benlloch, Sara, Giles, Graham G, Wiklund, Fredrik, Grönberg, Henrik, Haiman, Christopher A, Schleutker, Johanna, Nordestgaard, Børge G, Travis, Ruth C, Neal, David, Pasayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Blot, William J, Thibodeau, Stephen N, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R, Pandha, Hardev, Govindasami, Koveela, Muir, Ken, Easton, Douglas F, Eeles, Rosalind A, Kote-Jarai, Zsofia
Published in British journal of cancer (12.04.2016)
Published in British journal of cancer (12.04.2016)
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Journal Article
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer
Saunders, Edward J, Dadaev, Tokhir, Leongamornlert, Daniel A, Jugurnauth-Little, Sarah, Tymrakiewicz, Malgorzata, Wiklund, Fredrik, Al Olama, Ali Amin, Benlloch, Sara, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Giles, Graham G, Severi, Gianluca, Gronberg, Henrik, Aly, Markus, Haiman, Christopher A, Schumacher, Fredrick, Henderson, Brian E, Lindstrom, Sara, Kraft, Peter, Hunter, David J, Gapstur, Susan, Chanock, Stephen, Berndt, Sonja I, Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Nordestgaard, Børge G, Canzian, Federico, Campa, Daniele, Riboli, Elio, Key, Tim J, Travis, Ruth C, Ingles, Sue A, John, Esther M, Hayes, Richard B, Pharoah, Paul, Khaw, Kay-Tee, Stanford, Janet L, Ostrander, Elaine A, Signorello, Lisa B, Thibodeau, Stephen N, Schaid, Daniel, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y, Kaneva, Radka, Batra, Jyotsna, Clements, Judith A, Teixeira, Manuel R, Xu, Jianfeng, Mikropoulos, Christos, Goh, Chee, Govindasami, Koveela, Guy, Michelle, Wilkinson, Rosemary A, Sawyer, Emma J, Morgan, Angela, Easton, Douglas F, Muir, Ken, Eeles, Rosalind A, Kote-Jarai, Zsofia
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article
751OPREVALENCE OF HOXB13G84E GERMLINE MUTATION IN UK PROSTATE CANCER CASES; CORRELATION WITH TUMOUR CHARACTERISTICS AND OUTCOMES
Mikropoulos, C., Dadaev, T., Tymrakiewicz, M., Leongamornlert, D., Saunders, E., Little, S.J., Govindasami, K., Guy, M., Wilkinson, R., Morgan, A., Donovan, J., Neal, D., Hamdy, F., Antoniou, A., Eeles, R., Kote-Jarai, Z.
Published in Annals of oncology (01.09.2014)
Published in Annals of oncology (01.09.2014)
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Journal Article
Prevalence of Hoxb13G84E Germline Mutation in Uk Prostate Cancer Cases; Correlation with Tumour Characteristics and Outcomes
Mikropoulos, C., Dadaev, T., Tymrakiewicz, M., Leongamornlert, D., Saunders, E., Little, S.J., Govindasami, K., Guy, M., Wilkinson, R., Morgan, A., Donovan, J., Neal, D., Hamdy, F., Antoniou, A., Eeles, R., Kote-Jarai, Z.
Published in Annals of oncology (01.09.2014)
Published in Annals of oncology (01.09.2014)
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Journal Article
Prevalence of theHOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes
Kote-Jarai, Z., Mikropoulos, C., Leongamornlert, D.A., Dadaev, T., Tymrakiewicz, M., Saunders, E.J., Jones, M., Jugurnauth-Little, S., Govindasami, K., Guy, M., Hamdy, F.C., Donovan, J.L., Neal, D.E., Lane, J.A., Dearnaley, D., Wilkinson, R.A., Sawyer, E.J., Morgan, A., Antoniou, A.C., Eeles, R.A., Hall, Per, Berchuck, Andrew, Dennis, Joe, Dunning, Alison M., Lee, Andrew, Dicks, Ed, Simard, Jacques, Tessier, Daniel C., Bacot, Francois, Vincent, Daniel, LaBoissière, Sylvie, Robidoux, Frederic, Bojesen, Stig E., Nielsen, Sune F., Nordestgaard, Borge G.
Published in Annals of oncology (01.04.2015)
Published in Annals of oncology (01.04.2015)
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Journal Article
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
Amin Al Olama, Ali, Dadaev, Tokhir, Hazelett, Dennis J., Li, Qiuyan, Leongamornlert, Daniel, Saunders, Edward J., Stephens, Sarah, Cieza-Borrella, Clara, Whitmore, Ian, Benlloch Garcia, Sara, Giles, Graham G., Southey, Melissa C., Fitzgerald, Liesel, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Henderson, Brian E., Schumacher, Fredrick, Haiman, Christopher A., Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo L., Nordestgaard, Børge G., Key, Tim J., Travis, Ruth C., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L., Thibodeau, Stephen N., Mcdonnell, Shannon K., Schaid, Daniel J., Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S., Cybulski, Cezary, Wokołorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Park, Jong Y., Sellers, Thomas, Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A., Spurdle, Amanda, Teixeira, Manuel R., Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Govindasami, Koveela, Guy, Michelle, Lophatonanon, Artitaya, Muir, Kenneth, Viñuela, Ana, Brown, Andrew A., Freedman, Mathew, Conti, David V., Easton, Douglas, Coetzee, Gerhard A., Eeles, Rosalind A., Kote-Jarai, Zsofia
Published in Human molecular genetics (01.10.2015)
Published in Human molecular genetics (01.10.2015)
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Journal Article
Correlation of germ-line BRCA2 mutations with aggressive prostate cancer and outcome
Castro, E., Goh, C. L., Olmos, D., Leongamornlert, D., Saunders, E., Tymrakiewicz, M., Mahmud, N., Dadaev, T., Govindasami, K., Guy, M., OBrien, L., Sawyer, E., Hall, A., Wilkinson, R., Kote-Jarai, Z., Eeles, R. A.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Journal Article
Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Matejcic, M, Saunders, EJ, Dadaev, T, Brook, M, Al Olama, AA, Schumacher, FR, Berndt, SI, Benlloch, S, Muir, K, Govindasami, K, Stevens, VL, Gapstur, SM, Tangen, CM, Batra, J, Clements, J, Gronberg, H, Pashayan, N, Schleutker, J, Albanes, D, Wolk, A, West, C, Mucci, L, Kraft, P, Cancel-Tassin, G, Koutros, S, Sorensen, KD, Maehle, L, Grindedal, EM, Strom, S, Neal, DE, Hamdy, FC, Donovan, JL, Travis, RC, Hamilton, RJ, Ingles, SA, Rosenstein, B, Lu, YJ, Giles, GG, Kibel, AS, Vega, A, Bensen, J, Kogevinas, M, Wiklund, F, Chanock, S, Easton, DF, Eeles, RA, Kote-Jarai, Z, Conti, DV, Haiman, CA
Published in CANCER RESEARCH (2018)
Published in CANCER RESEARCH (2018)
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Conference Proceeding
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: Evidence for synthetic association in prostate cancer
Kote-Jarai, Z, Saunders, E, Dadaev, T, Leongamornlert, D, Jugurnauth-Little, S, Tymrakiewicz, M, Govindasami, K, Wiklund, F, Al Olama, AA, Benlloch, S, Easton, D, Muir, K, Eeles, R
Published in CANCER RESEARCH (2014)
Published in CANCER RESEARCH (2014)
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Conference Proceeding